Nursing care in the management of hypersensitivity reaction in patients undergoing antineoplastic therapy: review for clinical practice
DOI:
https://doi.org/10.33448/rsd-v9i7.4263Keywords:
Oncology; Drug hypersensitivity; Drug therapy; Nursing care.Abstract
Objective: To identify the scientific evidence available in the literature on nursing care for cancer patients who have hypersensitivity reactions during antineoplastic treatment, and thus describe the best practices for its management. Methods: Integrative review of the literature operated from July to September 2019 in the PUBMED, EMBASE, CINAHL AND LILACS databases, from the terms Oncology, drug hypersensitivity, drug therapy, nursing care. Results: The search resulted in5 studies, which specifically investigated the Nursing interventions in relation to hypersensitivity reactions. Based on evidence-based practice (EBS), a framework was built determining the best practices described in the literature. Among the interventions found were: previous assessment of the patient, rapid assessment of the degree of reaction, pause of drug infusion, airway assessment, good breathing and circulation, administration of physiological solution, oxygen therapy, corticoids and antihistamines according to institutional protocols and continuous assessment of vital signs. Conclusion: Oncologist nurses need to be properly trained in the management of hypersensitivity reactions and with the medical team to provide the patient with rapid and accurate assistance to minimize complications and grievances during treatment.
References
Arcuri, EAM. (1991). Reflexões sobre a responsabilidade do Enfermeiro na administração de medicamentos. Rev. Esc. Enfermagem USP, v.25, n.2, p. 229-37, ago. 1991.
Bonassa EMA, Gato MIR. (2012). Terapêutica Oncológica para enfermeiros e farmacêuticos. 4. ed. São Paulo: Atheneu.
BRASIL. Lei nº 7498 de 25 de Junho de 1986, que dispões sobre o Exercício profissional da Enfermagem, e dá outras providências. Acesso em 12 de Abril. Disponível em: HTTP://www.portalcofen.gov.br.
Gallimore, E. (2016). Infusion-related risks associated with chemotherapy. Nursing Standard. 30(25). 51-58. DOI: 10.7748/ns.30.25.51. s48.
Gomes ER, Demoly P. Epidemiology if hypersensitivity drug reactions. (2005) Curr Opin Allergy Clin Immunol. 2005; 5 (4): 309-16.
Jakel P, Carsten C, Braskett M, Carino A. (2016) Cuidados de Enfermagem de Pacientes Submetidos à Dessensibilização à Quimioterapia: Parte II. Revista Clínica de Enfermagem Oncológica. 20 (1): 29-32.
Joerger M. (2012). Prevention and handling of acute allergic and infusion reactions in oncology. Ann Oncol. 23 Suppl 10: 313-319.
Laudati, C., Clark, C., Knezevic, A., Zhang, Z. & Barton-Burke, M. (2018). Hypersensitivity Reactions: Priming practice change to reduce incidence in first-dose rituximab treatment .Clinical Journal of Oncology Nursing, 22 (4), 407-414.
Lenz HJ. (2007) Management and preparedness for infusion and hypersensitivity reactions. Oncologist 12:601-609.
Mayer M. Innovations in the management of infusion reactions: A new pharmacological approach to improve patient outcomes (2015). Cancer Nursing. 38 (4): S100-S1.
Melnyk BM, Fineout-Overholt E. (2005). Making the case for evidence-based practice. In: Melnyk BM, Fineout-Overholt E. Evidence-based practice in nursing & healthcare. A guide to best practice. Philadelphia: Lippincot Williams & Wilkins; p.3-24.
Mendes, KDS; Silveira, RCCP; Galvão, CM. (2008). Revisão integrati¬va: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto contexto - enferm. [In-ternet]. 2008; Dec; 17 (4):758-764. Disponível em: http:// www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-.
National Cancer Institute. (2017). Common Terminology Criteria for Adverse Events [v 5.0]. Disponível em: http://ctep.cancer.gov/protocoldevelopment/electronic.
Oncology Nursing Society (2019). Chemotherapy and Immunotherapy guidelines and recommendation for practice. ONS publication department. 2019. 261-262.
Passos P; Crespo A. (2011). Enfermagem Oncológica Antineoplásica. 1ª edição. São Paulo: Lemar.
Roselló, S.; Blasco, I.; García Fabregat, L.; Cervantes, A. & Jordan, K. (2017) .Management of infusion reactions to systemic anticancer therapy: ESMO clinical practice guidelines. Annals of Oncology. 28(4). 100-118.
Silva P, Heck AP, Silva BTD, Azambuja AA. (2015). O manejo das reações agudas em quimioterapia. Acta méd (Porto Alegre). 36:[6].
Vogel, W. H. (2010). Infusion reactions: Diagnosis, assessment and management. Clinical Journal of Oncology Nursing. 14(2). 10-21.
Zetka, E. S. (2012). The essentials of chemotherapy-induced infusion reactions. Clinical Journal of Oncology Nursing. 16(5). 527-529.
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