Botulinum toxin in the facial paralysis
DOI:
https://doi.org/10.33448/rsd-v12i7.42740Keywords:
Botulinum toxins, type A; Facial paralysis; Face.Abstract
Botulinum toxin is widely used in orofacial harmonization due to its aesthetic and therapeutic benefits. When applied correctly, it smooths facial wrinkles, improves facial contours, and treats conditions such as bruxism, gummy smile, and chronic migraines. Its temporary and reversible action makes it safe to improve the facial appearance and quality of life for patients. The mechanism of action of botulinum toxin involves blocking the release of the neurotransmitter acetylcholine, interrupting communication between nerves and muscles, resulting in localized muscle relaxation. Although temporary, the effect can be beneficial and nerve endings can regenerate over time. In addition, botulinum toxin is effective in the treatment of facial paralysis, improving facial symmetry, smoothing wrinkles and helping to recover muscle function. However, its use must be carried out by trained professionals, who will evaluate each case individually and follow safety protocols to obtain the best possible results. Thus, the objective of this narrative review of the literature is to analyze and gather scientific evidence on the use of botulinum toxin in orofacial harmonization and in the treatment of facial paralysis.
References
Agostini, F., Mangone, M., Santilli, V., Paoloni, M., Bernetti, A., Saggini, R., & Paolucci, T. (2020). Idiopathic facial palsy: umbrella review of systematic reviews and meta-analyses. Journal of biological regulators and homeostatic agents, 34(4), 1245–1255.
Bellows, S., & Jankovic, J. (2019). Immunogenicity Associated with Botulinum Toxin Treatment. Toxins, 11(9), 491.
Choudhury, S., Baker, M. R., Chatterjee, S., & Kumar, H. (2021). Botulinum Toxin: An Update on Pharmacology and Newer Products in Development. Toxins, 13(1), 58.
Cooper, L., Lui, M., & Nduka, C. (2017). Botulinum toxin treatment for facial palsy: A systematic review. Journal of plastic, reconstructive & aesthetic surgery, 70(6), 833–841.
de Jongh, F. W., Schaeffers, A. W. M. A., Kooreman, Z. E., Ingels, K. J. A. O., van Heerbeek, N., Beurskens, C., Monstrey, S. J., & Pouwels, S. (2023). Botulinum toxin A treatment in facial palsy synkinesis: a systematic review and meta-analysis. European archives of oto-rhino-laryngology, 280(4), 1581–1592.
Francisco Filho, M. L., Suguhiara, R. T., & Muknicka, D. P. (2023). Mecanismos de ação e indicações da Toxina Botulínica. Research, Society and Development, 12(6), e15712642223.
Fuzi, J., Taylor, A., Sideris, A., & Meller, C. (2020). Does Botulinum Toxin Therapy Improve Quality of Life in Patients with Facial Palsy? Aesthetic plastic surgery, 44(5), 1811–1819.
Hamidian Jahromi, A., & Konofaos, P. (2021). Contralateral Facial Botulinum Toxin Injection in Cases with Acute Facial Paralysis May Improve the Functional Recovery: Where We Stand and the Future Direction. World journal of plastic surgery, 10(2), 89–92.
Khan, A. J., Szczepura, A., Palmer, S., Bark, C., Neville, C., Thomson, D., Martin, H., & Nduka, C. (2022). Physical therapy for facial nerve paralysis (Bell's palsy): An updated and extended systematic review of the evidence for facial exercise therapy. Clinical rehabilitation, 36(11), 1424–1449.
Kim J. (2013). Contralateral botulinum toxin injection to improve facial asymmetry after acute facial paralysis. Otology & neurotology, 34(2), 319–324.
Matak, I., Bölcskei, K., Bach-Rojecky, L., & Helyes, Z. (2019). Mechanisms of Botulinum Toxin Type A Action on Pain. Toxins, 11(8), 459.
Nilforoushzadeh, M. A., Amirkhani, M. A., Zarrintaj, P., Salehi Moghaddam, A., Mehrabi, T., Alavi, S., & Mollapour Sisakht, M. (2018). Skin care and rejuvenation by cosmeceutical facial mask. Journal of cosmetic dermatology, 17(5), 693–702.
Penna, C. B., Suguhiara, R. T., & Muknicka, D. P. (2023). A toxina botulínica na harmonização orofacial. Research, Society and Development, 12(7), e4312742506.
Ramos, M. L. S., et al., (2022). A importância da conscientização sobre o uso da toxina botulínica tanto na atuação terapêutica, como na harmonização orofacial para cirurgiões dentistas. E-Acadêmica, 3(3), e4433344.
Robinson, M. W., & Baiungo, J. (2018). Facial Rehabilitation: Evaluation and Treatment Strategies for the Patient with Facial Palsy. Otolaryngologic clinics of North America, 51(6), 1151–1167.
Rother, E. T. (2007). Revisão sistemática x revisão narrativa. Acta Paul. Enferm, 20(2).
Salles, A. G., Mota, W. M., Remigio, A. F. D. N., de Andrade, A. C. H., & Gemperli, R. (2022). Management of Post-Facelift Facial Paralysis With Botulinum Toxin Type A. Aesthetic surgery journal, 42(3), NP144–NP150.
Serrera-Figallo, M. A., Ruiz-de-León-Hernández, G., Torres-Lagares, D., Castro-Araya, A., Torres-Ferrerosa, O., Hernández-Pacheco, E., & Gutierrez-Perez, J. L. (2020). Use of Botulinum Toxin in Orofacial Clinical Practice. Toxins, 12(2), 112.
Shim, Y. J., Lee, H. J., Park, K. J., Kim, H. T., Hong, I. H., & Kim, S. T. (2020). Botulinum Toxin Therapy for Managing Sleep Bruxism: A Randomized and Placebo-Controlled Trial. Toxins, 12(3), 168.
Sumodjo, P. R. P. A., Suguhiara, R. T., & Muknicka, D. P. (2023). O envelhecimento facial e a harmonização orofacial - uma revisão narrativa da literatura. Research, Society and Development, 12(5), e15312541591.
Watson, N. A., Siddiqui, Z., Miller, B. J., Karagama, Y., & Gibbins, N. (2021). Non-aesthetic uses of botulinum toxin in the head and neck. European archives of oto-rhino-laryngology, 278(11), 4147–4154.
Zhuang, J., Liu, T., & Hu, J. (2023). Herpes Zoster after Botulinum Toxin Combined with Hyaluronic Acid Injection. The Journal of craniofacial surgery, 34(5), 1503–1506.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Mariana Mendes Vilas Boas; Roberto Teruo Suguihara; Daniella Pilon Muknicka
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
