Gut-brain axis: relationship between intestinal microbiota and mental disorders

Authors

  • Ingrid Gabriela de Oliveira Tonini Centro Universitário Campo Real https://orcid.org/0000-0003-2568-8721
  • Diana Souza Santos Vaz Universidade Estadual de Campinas
  • Caryna Eurich Mazur Universidade Estadual do Centro-Oeste Guarapuava

DOI:

https://doi.org/10.33448/rsd-v9i7.4303

Keywords:

Anxiety; Depression; Gastrointestinal microbiome; Mental disorders.

Abstract

The term “gut-brain axis” has been widely used in the study of communication between the gastrointestinal tract and the central nervous system, a vital relationship for the maintenance of homeostasis and whose imbalance can result in changes in the response to stress and in behavior. This review aims to present and discuss the findings of studies about the gut-brain axis and the possible relationship between intestinal dysbiosis and mental disorders. The guiding question was: "How can intestinal health affect the brain and its functioning?" Of fifty articles found, seven were selected to integrate this review, all published in English. The findings of all articles discussed in this review demonstrate a direct and significant impact of the intestinal microbiota on the central nervous system, observing behaviors related to anxiety, depression and stress in the face of changes in the microbiota.

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Published

23/05/2020

How to Cite

TONINI, I. G. de O.; VAZ, D. S. S.; MAZUR, C. E. Gut-brain axis: relationship between intestinal microbiota and mental disorders. Research, Society and Development, [S. l.], v. 9, n. 7, p. e499974303, 2020. DOI: 10.33448/rsd-v9i7.4303. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/4303. Acesso em: 21 nov. 2024.

Issue

Section

Review Article