Main symptoms related to post-COVID syndrome, their reasons and physical therapy treatments

Authors

DOI:

https://doi.org/10.33448/rsd-v12i13.44419

Keywords:

Physhioterapy; Rehabilitation; Fatigue; Post-COVID; Dyspnea.

Abstract

The present study is a narrative bibliographical review on persistent symptoms in the post-COVID period, aiming to generate understanding of such symptoms, thus showing the importance of physiotherapeutic rehabilitation programs. More than 200 symptoms are associated with post-COVID, thus weakening the quality of life of the individual affected by the disease, making simple tasks become complex as a result of the consequences of COVID-19. Post-COVID causes pathophysiological and systemic impairments, this study aims to identify the two main symptoms found in post-COVID, as well as understand the likely mechanism involved in the persistence of such symptoms, thus ensuring that physiotherapeutic rehabilitation programs are created with a focus on in the functional improvement of the affected individual. Wasserman and colleagues initially proposed a gear model that illustrated the integrated role of systems. Articles were analyzed which pointed out that the majority of people infected by COVID-19 present mild to moderate symptoms, and there are a portion of individuals who face the severe version of the disease and need hospital interventions. For these, the problems do not end when the virus disappears from the body, they present several symptoms with a greater predominance of fatigue and dyspnea, generated by deficits in several physiological systems. Such changes fit into the gear model that illustrates the role of the respiratory systems, cardiovascular and skeletal muscle. This finding is of fundamental importance for developing rehabilitation programs focused on improving the patient's ADL and full functional recovery.

References

Arena, R., Myers, J., Ozemek, C., Hall, G., Severin, R., Laddu, D., Kaminsky, L. A., Stoner, L., Conners, R. T., & Faghy, M. A. (2022). An evolving approach to assessing cardiorespiratory fitness, muscle function and bone and joint health in the COVID-19 era. Current Problems in Cardiology, 47(1), 100879. https://doi.org/10.1016/j.cpcardiol.2021.100879

Agergaard, J., Leth, S., Pedersen, T. H., Harbo, T., Blicher, J. U., Karlsson, P., Østergaard, L., Andersen, H., & Tankisi, H. (2021). Myopathic changes in patients with long-term fatigue after COVID-19. Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology, 132(8), 1974–1981. https://doi.org/10.1016/j.clinph.2021.04.009

Barash, M., & Ramalingam, V. (2023). Post-COVID interstitial lung disease and other lung sequelae. Clinics in Chest Medicine, 44(2), 263–277. https://doi.org/10.1016/j.ccm.2022.11.019

Besnier, F., Bérubé, B., Malo, J., Gagnon, C., Grégoire, C.-A., Juneau, M., Simard, F., L’Allier, P., Nigam, A., Iglésies-Grau, J., Vincent, T., Talamonti, D., Dupuy, E. G., Mohammadi, H., Gayda, M., & Bherer, L. (2022). Cardiopulmonary rehabilitation in long-COVID-19 patients with persistent breathlessness and fatigue: The COVID-Rehab study. International Journal of Environmental Research and Public Health, 19(7), 4133. https://doi.org/10.3390/ijerph19074133

Batista, A. R., Mendes, D. dos S., Lima, F. A. de, Silva, G. G., Marcate, T. B., & Boaretto, F. R. F. (2022). Protocolo de reabilitação da síndrome pós-COVID-19 na atenção primária. Research, Society and Development, 11(13), e342111335400. https://doi.org/10.33448/rsd-v11i13.35400

Del Corral, T., Fabero-Garrido, R., Plaza-Manzano, G., Fernández-de-las-Peñas, C., Navarro-Santana, M., & López-de-Uralde-Villanueva, I. (2023). Home-based respiratory muscle training on quality of life and exercise tolerance in long-term post-COVID-19: Randomized controlled trial. Annals of Physical and Rehabilitation Medicine, 66(1), 101709. https://doi.org/10.1016/j.rehab.2022.101709 1

Davis, E.H., Assafa, G. S., McCorkell, L., Wei, H., Low R.J., Re'ema Y., Redfielda, S., Austin, J.P & Akramia, A. (2021). Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. ECclinicalMedicine , 38, 101019. ttps://doi.org/10.1016/j.eclinm.2021.101019

Gallegos, M., Martino, P., Caycho-Rodríguez, T., Calandra, M., Razumovskiy, A., Arias-Gallegos, W. L., de Castro-Peçanha, V., & Cervigni, M. (2022). ¿Qué es el síndrome pos-COVID-19? Definición y actualización. Gaceta médica de Mexico, 158(6), 451–455. https://doi.org/10.24875/gmm.22000144

Haberland, E., Haberland, J., Richter, S., Schmid, M., Hromek, J., Zimmermann, H., Geng, S., Winterer, H., Schneider, S., & Kollum, M. (2022). Seven months after mild COVID-19: A single-centre controlled follow-up study in the district of Constance (FSC19-KN). International Journal of Clinical Practice, 2022, 1–8. https://doi.org/10.1155/2022/8373697

Joli, J., Buck, P., Zipfel, S., & Stengel, A. (2022). Post-COVID-19 fatigue: A systematic review. Frontiers in psychiatry, 13. https://doi.org/10.3389/fpsyt.2022.947973

Karsten, M., Matte, DL, & de Andrade, FMD (2020). A pandemia da COVID-19 trouxe desafios e novas possibilidades para a Fisioterapia no Brasil: estamos preparados? Revista Pesquisa em Fisioterapia, 10 (2), 142-145. https://doi.org/10.17267/2238-2704rpf.v10i2.2971

Matheson, A. M., McIntosh, M. J., Kooner, H. K., Lee, J., Desaigoudar, V., Bier, E., Driehuys, B., Svenningsen, S., Santyr, G. E., Kirby, M., Albert, M. S., Shepelytskyi, Y., Grynko, V., Ouriadov, A., Abdelrazek, M., Dhaliwal, I., Nicholson, J. M., & Parraga, G. (2022). Persistent 129Xe MRI pulmonary and CT vascular abnormalities in symptomatic individuals with post-acute COVID-19 syndrome. Radiology, 305(2), 466–476. https://doi.org/10.1148/radiol.220492

Mittal, J., Ghosh, A., Bhatt, S. P., Anoop, S., Ansari, I. A., & Misra, A. (2021). High prevalence of post COVID-19 fatigue in patients with type 2 diabetes: A case-control study. Diabetes & Metabolic Syndrome, 15(6), 102302. https://doi.org/10.1016/j.dsx.2021.102302

Morrow, A., Gray, S. R., Bayes, H. K., Sykes, R., McGarry, E., Anderson, D., Boiskin, D., Burke, C., Cleland, J. G. F., Goodyear, C., Ibbotson, T., Lang, C. C., Connachie, M., Mair, F., Mangion, K., Patel, M., Sattar, N., Taggart, D., Taylor, R., & Berry, C. (2022). Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise—CISCO-21. Trials, 23(1). https://doi.org/10.1186/s13063-022-06632-y

Martinez, B. P., Andrade, F. M. D. de, Martins, J. A., Matte, D. L., & Karsten, M. (2020). Papel do Fisioterapeuta em diferentes cenários de atuação à COVID-19. ASSOBRAFIR Ciência, 11(Supl1), 27. https://doi.org/10.47066/2177-9333.ac20.covid19.003

Nopp, S., Moik, F., Klok, F. A., Gattinger, D., Petrovic, M., Vonbank, K., Koczulla, A. R., Ay, C., & Zwick, R. H. (2022). Outpatient pulmonary rehabilitation in patients with long COVID improves exercise capacity, functional status, dyspnea, fatigue, and quality of life. Respiration; International Review of Thoracic Diseases, 101(6), 593–601. https://doi.org/10.1159/000522118

Nunes, W. M. P., & Santos, J. S. (2023). Atuação farmacêutica em práticas integrativas: Uma revisão. Research, Society and Development, 12(8), e1612842835. https://doi.org/10.33448/rsd-v12i8.42835

Graça, N. P., Viscont, N. R. G. R., Santos, M. I. V., Capone, D., Cardoso, A. P., & Mello, F. C. Q. (2020). COVID-19: Seguimento após a alta hospitalar. Pulmão RJ, 29(1), 32-36. http://www.sopterj.com.br/wp-content/themes/_sopterj_redesign_2017/_revista/2020/artigo-6-COVID-19%20Seguimento%20ap%C3%B3s%20a%20alta%20hospitalar.pdf

Salari, N., Khodayari, Y., Hosseinian-Far, A., Zarei, H., Rasoulpoor, S., Akbari, H., & Mohammadi, M. (2022). Global prevalence of chronic fatigue syndrome among long COVID-19 patients: A systematic review and meta-analysis. BioPsychoSocial Medicine, 16(1). https://doi.org/10.1186/s13030-022-00250-5

Schwendinger, F., Knaier, R., Radtke, T., & Schmidt-Trucksäss, A. (2023). Low cardiorespiratory fitness post-COVID-19: A narrative review. Sports Medicine (Auckland, N.Z.), 53(1), 51–74. https://doi.org/10.1007/s40279-022-01751-7

Szarvas, Z., Fekete, M., Horvath, R., Shimizu, M., Tsuhiya, F., Choi, H. E., Kup, K., Fazekas-Pongor, V., Pete, K. N., Cserjesi, R., Bakos, R., Gobel, O., Kovacs, O., Gyongyosi, K., Pinter, R., Kovats, Z., Ungvari, Z., Tarantini, S., Horvath, G., & Varga, J. T. (2023). Cardiopulmonary rehabilitation programme improves physical health and quality of life in post-COVID syndrome. Annals of Palliative Medicine, 12(3), 548–560. https://doi.org/10.21037/apm-22-1143

Saes, M. O. (2021). Covid longa. Rev vittalle revista de ciências da saúde 33 (3) 7-8 https://periodicos.furg.br/vittalle/article/download/13833/9162/45671.

Torres, D. da C., Avila, P. E. S., & Pereira, R. do N. (2020). Guia de orientações fisioterapêuticas na assistência ao paciente pós-COVID-19. https://livroaberto.ufpa.br/jspui/handle/prefix/833

Schaeffer, M. R., Cowan, J., Milne, K. M., Puyat, J. H., Voduc, N., Corrales-Medina, V., Lavoie, K. L., Mulloy, A., Chirinos, J. A., Abdallah, S. J., & Guenette, J. A. (2022). Cardiorespiratory physiology, exertional symptoms, and psychological burden in post-COVID-19 fatigue. Respiratory Physiology & Neurobiology, 302(103898), 103898. https://doi.org/10.1016/j.resp.2022.103898

Wasserman K. The Dickinson W. (1988). Richards lecture. New concepts in assessing cardiovascular function. Circulation 78(4):1060–171

Yong, S. J., & Liu, S. (2022). Proposed subtypes of post‐COVID‐19 syndrome (or long‐COVID) and their respective potential therapies. Reviews in medical virology, 32(4), e2315 https://periodicos.furg.br/vittalle/article/download/13833/9162/45671.

Published

10/12/2023

How to Cite

SOARES, G. E. F. .; PEREIRA, R. C. dos S. .; ALMEIDA, R. C. de . Main symptoms related to post-COVID syndrome, their reasons and physical therapy treatments . Research, Society and Development, [S. l.], v. 12, n. 13, p. e146121344419, 2023. DOI: 10.33448/rsd-v12i13.44419. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/44419. Acesso em: 22 nov. 2024.

Issue

Section

Review Article