Lymphoplasmocytic gastritis and duodenitis in a dog: Case report

Authors

DOI:

https://doi.org/10.33448/rsd-v13i1.44792

Keywords:

Inflammatory bowel disease; Chronic inflammatory enteropathy; Dysbiosis; Lymphoplasmocytic hyperplastic gastritis; Lymphoplasmocytic erosive duodenitis.

Abstract

Inflammatory Bowel Disease (IBD) or Chronic Inflammatory Enteropathy in dogs is characterized by chronic inflammatory alterations of the gastrointestinal tract, with a multifactorial etiology and challenging diagnosis. Among the most common causes of IBD are factors such as genetic predisposition, dysbiosis, increased gut permeability, and environmental factors. The clinical signs are nonspecific, recurrent, or persistent, including vomiting, diarrhea, weight loss, and appetite alterations for more than three weeks. Diagnosis is usually based on the exclusion of differential pathologies, anamnesis, and complementary exams. The treatment may involves dietary modification and medications such as corticosteroids, immunosuppressants, antibiotics, and supportive therapy with nutraceuticals. The prognosis of the disease depends on the type of enteropathy and its severity. This study aims to report the process of clinical investigation regarding a case of hyperplastic gastritis and erosive duodenitis lymphoplasmacytics, presented in a seven-year-old male Dachshund with a clinical history of chronic diarrhea and sporadic bilious vomiting. The methodology used in this article refers to a descriptive observational study of the case report type. The investigation of clinical signs involved making a diagnosis by exclusion, and suggesting a definitive diagnosis. Proper treatment and prognosis for IBD were initiated. Currently, the canine remains under treatment and stable.

References

Allenspach, K. & Mochel, P. J. (2021). Current diagnostics for chronic enteropathies in dogs. Veterinary Clinical Pathology. 50, 18-28. https://pubmed.ncbi.nlm.nih.gov/34699081/.

Artacho, S. N. & Silva, D. R. (2023). Doenças do intestino delgado: diarreias agudas. In: Jericó, M.M; Neto, A.P.J. & Kogika, M.M. Tratado de Medicina Interna de Cães e gatos. Guanabara Koogan, 1052-1055.

Artacho, S. N. & Silva, D. R. (2023). Doenças do intestino delgado: diarreias crônicas. In: Jericó, M.M; Neto, A.P.J. & Kogika, M.M. Tratado de Medicina Interna de Cães e gatos. Guanabara Koogan, 1056-1059.

Bastan, I., et al. (2017). Assessment of eosinophil peroxidase as a potential diagnostic and prognostic marker in dogs with inflammatory bowel disease. American Journal of Veterinary Research. 78(1), 36-41. https://pubmed.ncbi.nlm.nih.gov/28029282/.

Bottero, E., et al. (2022). Clinical evaluation and microbiota analysis in 9 dogs with antibiotic-responsive enteropathy: A prospective comparison study. Journal of Veterinary Internal Medicine. 36(4), 1220-1228. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308422/.

Cave, N. (2013). Gastrointestinal gas: Eructation, borborygmus and flatulence. In: Washabau, J.R.& Day, J.M. Canine and Feline Gastroenterology. Elsevier, 124 – 128.

Cerquetella, M., et al. (2010). Inflammation bowel disease in dog: differences and similarities with humans. World Journal of Gastroenterology. 16(9), 1050-1056. https://www.wjgnet.com/1007-9327/full/v16/i9/1050.htm.

Collins, T. M. (2013). Canine Inflammatory Bowel disease: Current and prospective Biomarkers for Diagnosis and Management. Compedium: Continuing Education for Veterinarians. 35. https://pubmed.ncbi.nlm.nih.gov/23532922/.

Dandrieux, S. R. J. (2016). Inflammatory bowel disease versus chronic enteropathy in dogs: are they one and the same? Journal of Small Animal Practice. 57(11), 589-599. https://onlinelibrary.wiley.com/doi/10.1111/jsap.12588.

Day, J. M. (2013). Gastrointestinal inflammation. In: Washabau, J. R. & Day, J. M. Canine and Feline Gastroenterology. Elsevier, 54-59.

Duarte, R. (2020). Disbiose intestinal canina: diagnóstico e tratamento. Informativo técnico. PremieRvet. (3a ed.), 2-7. https://www.premierpet.com.br/wp-content/uploads/2020/11/Disbiose-intestinal-canina-Diagnostico-e-tratamento.pdf.

Erdmann, C. & Heilmann, M. R. (2017). Diagnostic and therapeutic approach to chronic inflammatory enteropathies in dogs. Tierarztl Prax Ausg K Kleintiere Heimtiere. 45, 317-327. https://pubmed.ncbi.nlm.nih.gov/28933796/.

Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa. Editora Artes Médicas.

German, J. A. (2013). Small Intestine: inflammation. In: Washabau, J. R.& Day, J.M. Canine and Feline Gastroenterology. Elsevier, 669-678.

Guex, R. G. (2020) Helmintoses intestinais em caninos no Brasil – revisão de artigos publicados no período de 2013 a 2019. Revista Agrária Acadêmica. 3,(1). https://agrariacad.com/wp-content/uploads/2020/04/Rev-Agr-Acad-v3-n1-2020-p144-161-Helmintoses-intestinais-em-caninos-no-Brasil-%E2%80%93-revisao-de-artigos-publicados-no-periodo-de-2013-a-2019.pdf.

Hall, J. E. & German, J. A. (2008). Inflammatory Bowel Disease. In: Steiner, M. J. Small Animal Gastroenterology. Germany: Schlütersche, 2008. p. 312-327.

Heilmann, R., et al. (2018). Association of fecal calprotectin concentrations with disease severity, response to treatment, and other biomarkers in dogs with chronic inflammatory enteropathies. Journal of Veterinary Internal Medicine. 32, (2). https://pubmed.ncbi.nlm.nih.gov/29460444.

Holmberg, J., et al. (2022). Chronic Enteropathy in dogs – Epidemiologic Aspects and Clinical characteristics of dogs presenting at two Swedish Animal Hospitals. Animals. 12(12), 1507. https://pubmed.ncbi.nlm.nih.gov/35739843/.

Husnik, R. et al. (2022). Helicobacter Species and their association with Gastric Pathology in a Cohort of Dogs with Chronic Gastrointestinal signs. Animals. 12, (1254). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9137851/.

Jergens, E. A. & Heilmann, M. R. (2022). Canine chronic enteropathy – Current state-of-the-art and emerging concepts. Frontiers in Veterinary Science. vol.9. https://www.frontiersin.org/articles/10.3389/fvets.2022.923013/full.

Magalhães, P. L. M. T. (2008). Enterite linfoplasmocítica canina. Dissertação de Mestrado Integrado em Medicina Veterinária. Universidade Técnica de Lisboa, p. 121. https://www.repository.utl.pt/bitstream/10400.5/947/1/Enterite%20Linfoplasmoc%C3%ADtica%20Canina.pdf.

Marks, L. S. (2013). Diarrhea. In: Washabau, J.R. & Day, J.M. Canine and Feline Gastroenterology. Missouri: Elsevier, 99-108.

Niina, A., et al. (2020). Fecal microbiota transplantation as a new treatment for canine inflammatory bowel disease. Bioscience of Microbiota, Food and Health. 40, (2), 98-154. https://www.jstage.jst.go.jp/article/bmfh/40/2/40_2020-049/_article.

Pappalardo, F. C. M & Auler, B. A. F. (2023). Doenças Gástricas. In: Jericó, M.M; Neto, A.P.J.& Kogika, M.M. Tratado de Medicina Interna de Cães e gatos. Guanabara Koogan, 1044-1051.

Perrucci, S., et al. (2020). Giardia duodenalis infection in dogs affected by primary chronic enteropathy. Open Veterinary Journal. 10, 74-79. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193877/.

Sahoo, K. D., et al. (2022). Synbiotic-IgY Theraphy modulates the mucosal microbiome and inflammatory indices in dogs with Chronic Inflammatory Enteropathy: A randomized, double-blind, placebo-controlled study. Veterinary Sciences. 10, (1). https://pubmed.ncbi.nlm.nih.gov/36669027/.

Siel, D., et al. (2022). Elucidating the role Innate and Adaptative immune responses in the pathogenesis of Canine Chronic Inflammatory Enteropathy – A search for potential biomarkers. Animals. 12, (13), 1645. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264988/.

Silva, P. C. K. M., et al. (2022). Atividade cicatrizante e antioxidante da Maytenus ilicifolia (espinheira-santa): uma revisão. Research, Society and Development. 1, (14). https://rsdjournal.org/index.php/rsd/article/view/36604.

Simpson, W. K. (2013). Stomach: structure and function. In: Washabau, J.R.& Day, J.M. Canine and Feline Gastroenterology. Elsevier, 606-609.

Spohr, A. (2013). Stomach: diagnostic evaluation. In: Washabau, J.R.& Day, J.M. Canine and Feline Gastroenterology. Missouri: Elsevier, 609 – 615.

Suchodolski, S. J. (2016). Diagnosis and interpretation of intestinal dysbiosis in dogs and cats. The Veterinary Journal. 215, 30-37. https://pubmed.ncbi.nlm.nih.gov/27160005/.

Suchodolski, S. J. (2013). Gastrointestinal microbiota. In: Washabau, J.R. & Day, J.M. Canine and Feline Gastroenterology. Elsevier, 32- 41.

Titmarsh, A. G., et al. (2015). Association of Vitamin D status and clinical outcome in dogs with chronic enteropathy. Journal of Veterinary Internal Medicine. 29, 1473-1478. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895651/.

Washabau, J. R. (2013). Large Intestine. In: Washabau, J. R.& Day, J.M. Canine and Feline Gastroenterology. Elsevier, 729-744.

Westermarck, E. (2008). Chronic Diarrhea. In: Steiner, M. J. Small Animal Gastroenterology. Schlütersche, 132 -133.

WSAVA, World Small Animal Veterinary Association. (2010). Endoscopic, biopsy, and histopathologic guidelines for the avaluation of Gastrintestinal Inflamation in companion animals. Consensus Statements of the American College of Veterinary Internal Medicine (ACVIM). Journal of Veterinary Internal Medicine. 24. https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1939-1676.2009.0443.x.

Published

19/01/2024

How to Cite

OLIVEIRA, C. R. de .; VOLKWEIS, F. S. . Lymphoplasmocytic gastritis and duodenitis in a dog: Case report. Research, Society and Development, [S. l.], v. 13, n. 1, p. e8613144792, 2024. DOI: 10.33448/rsd-v13i1.44792. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/44792. Acesso em: 27 may. 2024.

Issue

Section

Agrarian and Biological Sciences