Physiotherapy performance after treatment of telangectatic osteosarcoma with total endoprosthesis of the femur with acetabulum, knee joint and tibial componente: Case report
DOI:
https://doi.org/10.33448/rsd-v13i2.45061Keywords:
Osteosarcoma; Prosthetics and implants; Hospital physiotherapy service.Abstract
Objective: retrospective analysis of the functional results of a patient diagnosed with bone sarcoma in the distal end of the femur, who underwent reconstruction with a total knee endoprosthesis. Methodology: The article is an observational, retrospective and descriptive case report of a patient with osteosarcoma in the distal end of the femur, who underwent reconstruction with a total knee endoprosthesis. The methodology included analysis of signs, symptoms, pathophysiology, complications, physiotherapeutic treatment and information from medical records. Case Report: The patient, diagnosed at the age of 38, went through a complex process, from the discovery of the tumor to surgery to remove the affected bone and implant a total femur and tibia endoprosthesis. The report highlights the evolution, complications and the patient's current dependence to carry out daily activities. Discussion: The increased survival of patients with endoprostheses raises questions about frequent revisions, complications and surgical preferences. The choice between partial and total endoprosthesis is discussed, considering criteria such as age, location and extent of the tumor. Reconstruction of the lower limb with a non-conventional endoprosthesis provides early ambulation, but durability varies. Conclusion: The study concludes that surgical techniques with endoprostheses, whether total or partial, are effective in preventing amputations, improving the quality of life of patients with osteosarcoma. It highlights the importance of physiotherapy in the post-operative period and suggests the need for more studies for early diagnoses, avoiding amputations and promoting better treatments for cancer patients.
References
Abdulelah, A. A., et al. (2023). The risk of reveloping osteosarcoma after teriparatide use: A systematic review. Orthop Res Rev. 27, 191-198.
Casone, A. E. (2008). Tumores malignos formadores de tecido ósseo: Osteossarcoma. Acta ortop. bras. 16, 13-18.
Croci, A. T., et al. (2000). The use of a modular titanium endoprosthesis in skeletal reconstructions after bone tumor resections: method presentation and analysis of 37 cases. Rev Hosp Clin Fac Med. 55, 169-76.
Davis, L. E., et al. (2019). Randomized double-blind phase II study of regorafenib in patients with metastatic osteosarcoma. J Clin Oncol. 16, 1424-1431.
Entz, N., et al. (2003). Genetic alterations in primary osteosarcoma from 54 children and adolescentes by target allelotyping. Br J Cancer. 88, 1925-1931.
Gazouli, I., et al. (2021). Systematic Review of Recurrent Osteosarcoma Systemic Therapy. Cancers (Basel). 13, 1757-1758.
Hingorani, P., et al. (2022). Phase 2 study of anti-disialoganglioside antibody, dinutuximab, in combination with GM-CSF in patients with recurrent osteosarcoma: A report from the Children's Oncology Group. Eur J Cancer. 172, 264-275.
Hurkmans, E., et al. (2022). Pharmacogenetics of chemotherapy treatment response and -toxicities in patients with osteosarcoma: a systematic review. BMC Cancer. 22, 1324-1326.
Italiano, A., et al. (2020). Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial. Lancet Oncol. 21, 446-455.
Liu, H., Gao, X., & Hou, Y. (2019). Effects of mindfulness-based stress reduction combined with music therapy on pain, anxiety, and sleep quality in patients with osteosarcoma. Braz J Psychiatry. 41, 540-545.
Marina, N., Gebhardt, M., Teot, L., & Gorlick, R. (2004). Biology and therapeutic advances for pediatric osteosarcoma. Oncolgist. 9, 422-41.
Mendonça S., et al. (2022). Avaliação funcional dos pacientes portadores de sarcomas ósseos submetidos à tratamento cirúrgico utilizando a endoprótese total ou parcial, na substituição da extremidade distal do fêmur. Acta Ortopédica Brasileira. 16, 13–18.
Mercuri, M., et al. (1991). The management of malignant bone tumors in children and adolecents. Clin Orthop Relat Res. 264, 156-158.
Pacheco, M., Guzmán, R., & Bonilla, P. (2022). Dedifferentiated Low-Grade Osteosarcoma, Outcome with or Without Chemotherapy: A Systematic Review. Orthop Res Rev. 28, 79-89.
Pereira, C. M., et al. (2022). Reconstruction with Unconventional Endoprostheses after Resection of Primary Distal Femoral Bone Tumors: Implant Survival and Functional Outcomes. Revista Brasileira De Ortopedia. 57, 1030–1038.
Pritchard, J., Dahlin, D, & Dauphine, R. (1975). Ewing’s sarcoma: a clinicopathologic and statistical analysis of patients surviving five years or longer. J Bone Joint Surg Am. 10-16.
Puig, G., et al. (2022). Factores hereditarios y síndromes de predisposición genética relacionados con sarcomas de partes blandas. Medisan. 1, 190-203
Rosen, G., Murphy, M., et al. (1976) Chemotherapy, em bloc resections and prosthetic bone replacement in the treatment of osteogenic sarcoma. Cancer. 101-110.
Smeland, S., et al. (2019). Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort. Eur J Cancer. 109; 36-50.
Wang, J., et al. (2022). A Nomogram for Predicting Cancer-Specific Survival of Osteosarcoma and Ewing's Sarcoma in Children: A SEER Database Analysis. Front Public Health. 10, 75-80.
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Copyright (c) 2024 Amanda Ferreira Alves; Higor Gregore Alencar Oliveira; Káren Andresa Mendes da Silva; Ellene Cristine Lopes de Oliveira ; Moisés Francisco do Carmo ; Mário José de Rezende; Eduardo Alexandre Loth
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