Complications generated by HIV/AIDS in pregnancy: An integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v13i2.45120

Keywords:

Pregnancy; Acquired Immunodeficiency Syndrome; HIV infections; Infectious complications of pregnancy; AIDS.

Abstract

Objective: To describe the main gestational complications presented by pregnant women living with HIV/AIDS. Methodology: This is an integrative, descriptive literature review study, constructed from a scientific database (PubMed, Scielo and Virtual Health Library - VHL). Inclusion criteria were considered: studies related to the consequences/complications of pregnant women living with HIV, available in free full text, published between 2018 and 2022. Excluded were: duplicate works, outside the period in question, with full text unavailable and inappropriate after reading. Results: After adequate screening of the 736 articles found, 11 studies were selected for analysis. These were arranged in a table with year, title, authors, objectives and main results. Its critical analysis allowed us to understand complications associated with HIV in pregnant women, such as: maternal mortality, fetal mortality, low neonatal birth weight, premature birth, increased risk of cesarean section, among others. Conclusion: It was found that such complications make the presence of infection during pregnancy a public health problem, which requires adequate prenatal care in order to avoid such complications for mother and baby.

References

Amorim, T., Duarte, L. & Da Silva. (2021). Perfil epidemiológico de casos notificados de hiv no estado de Goiás. RESAP - Rev Cient Esc Estadual de Saúde Pública "Cândido Santiago”. 7, e7000043. https://docs.bvsalud.org/biblioref/2021/10/1292642/perfil-epidemiologico-de-casos-notificados-de-hiv-no-estado-de-goias.pdf.

Andiman, W. A. (2020). Where Have All the “AIDS Babies” Gone? A Historical Memoir of the Pediatric AIDS Epidemic in New Haven and its Eventual Eradication. The Yale Journal of Biology and Medicine, 93(4), 625–635. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513449/

Anoubissi, J. de D., Gabriel, E. L., Kengne Nde, C., Fokam, J., Tseuko, D. G., Messeh, A., Moussa, Y., Nkenfou, C. N., Bonono, L., Billong, S.-C. & Nfetam, J.-B. E. (2019). Factors associated with risk of HIV-infection among pregnant women in Cameroon: Evidence from the 2016 national sentinel surveillance survey of HIV and syphilis. PLOS ONE. 14 (4), e0208963. https://doi.org/10.1371/journal.pone.0208963“

Brasil, U. (2016). Adesão de cidades à Declaração de Paris já beneficia 35 mi de brasileiras e brasileiros - UNAIDS Brasil. https://unaids.org.br/2016/03/adesao-de-cidades-a-declaracao-de-paris-ja-beneficia-35-mi-de-brasil

Brasil. (2020). Portaria SCTIE/MS No 55, de 11 de novembro de 2020. Ministério da Saúde. https://www.gov.br/conitec/pt-br/midias/protocolos/20201113_pcdt_para_ptv_hiv_final.pdf

Brasil. (2021). HIV/Aids | 2021. https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/especiais/2021/boletim-epidemiologico-especial-hiv-aids-2021.pdf/@@download/file

Bailey, H., Zash, R., Rasi, V., & Thorne, C. (2018). HIV treatment in pregnancy. The Lancet HIV, 5(8), e457–e467. https://doi.org/10.1016/s2352-3018(18)30059-6

Bandera, A., Gori, A., Clerici, M., & Sironi, M. (2019). Phylogenies in ART: HIV reservoirs, HIV latency and drug resistance. Current Opinion in Pharmacology, 48, 24–32. https://doi.org/10.1016/j.coph.2019.03.003

Cambrea, S. C., Marcu, E. A., Cucli, E., Badiu, D., Penciu, R., Petcu, C. L., Dumea, E., Halichidis, S., Pazara, L., Mihai, C. M., & Dumitrescu, F. (2022). Clinical and Biological Risk Factors Associated with Increased Mother-to-Child Transmission of HIV in Two South-East HIV-AIDS Regional Centers in Romania. Medicina, 58(2), 275. https://doi.org/10.3390/medicina58020275

Carmo, R. A. do, Policena, G. M., Alencar, G. P., França, E. B., & Bierrenbach, A. L. (2021). Subnotificação de óbitos por AIDS no Brasil: linkage dos registros hospitalares com dados de declaração de óbito. Ciência & Saúde Coletiva, 26(4), 1299–1310. https://doi.org/10.1590/1413-81232021264.15922019

Curing HIV: Seeking to Target and Clear Persistent Infection. (2020). Cell, 181(1), 189–206. https://doi.org/10.1016/j.cell.2020.03.005

Davoglio, R. S., Gandin, H., & Mocellin, L. P. (2021). Epidemia de HIV/aids em município da fronteira oeste do Rio Grande do Sul, Brasil: evolução, cascata de cuidados e letalidade. Revista Brasileira de Epidemiologia, 24, e210018. https://www.scielo.br/j/rbepid/a/ZTqMz6xCQGDrRNQKVPbTJph/abstract/?lang=pt

HIV/Aids | 2022 Secretaria de Vigilância em Saúde | Ministério da Saúde Boletim Epidemiológico. (n.d.). https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/especiais/2022/boletim-epidemiologico-de-hiv-aids-numero-especial-dez-2022/@@download/file

Kodan, P., Gupta, N., Ratna, S., Ramprasad, A., Ranjan, S., Nischal, N., Soneja, M., & Wig, N. (2020). Perinatal transmission in Human Immunodeficiency Virus infection: a cross-sectional study from a tertiary care center in North India. Le Infezioni in Medicina, 28(2), 227–230. https://pubmed.ncbi.nlm.nih.gov/32487787/

Mandu, J. B. dos S., Marcon, S. S., Arruda, G. O. de, Negri, A. C. G., Souza, I. M. de, & Teston, E. F. (2022). Para além da busca ativa: motivações para retorno ao tratamento de HIV [Beyond active search: motivations for returning to HIV treatment] [Más allá de la búsqueda activa: motivaciones para volver al tratamiento del VIH]. Revista Enfermagem UERJ, 30, e68710–e68710. https://doi.org/10.12957/reuerj.2022.68710

Muthelo, L., Mgwenya, J. P., Malema, R. N., & Mothiba, T. (2020). How is becoming pregnant whilst HIV-positive? Voices of women at a selected rural clinic in Mpumalanga Province of South Africa. SAHARA-J: Journal of Social Aspects of HIV/AIDS, 17(1), 30–37. https://doi.org/10.1080/17290376.2020.1857299

Musarandega, R., Machekano, R., Pattinson, R., & Munjanja, S. P. (2021). Protocol for analysing the epidemiology of maternal mortality in Zimbabwe: A civil registration and vital statistics trend study. PLOS ONE, 16(6), e0252106. https://doi.org/10.1371/journal.pone.0252106

Neto, S. (2020). Dinâmica das Doenças Infecciosas. https://doi.org/10.22533/at.ed.018201604

Nogueira López, J., Prieto-Tato, L., Escosa-García, L., Bernardino, J. I., Muñoz, E., Díez, C., Carrasco, I., Ryan, P., Guillén-Martín, S., Ramos-Amador, J. T., Navarro, M. L., Holguín, A., Sainz, T., & CoRISpe Group. (2022). Pregnancy Outcomes Among Perinatally HIV-Infected Women in Spain. Journal of Acquired Immune Deficiency Syndromes (1999), 91(4), 373–380. https://doi.org/10.1097/QAI.0000000000003070

Oliveira, M. I. C. de, Silva, K. S., & Gomes, D. M. (2018). Fatores associados à submissão ao teste rápido anti-HIV na assistência ao parto. Ciência & Saúde Coletiva, 23(2), 575–584. https://doi.org/10.1590/1413-81232018232.11612016

Pompeu, H. H. F. A., Moraes, L. P. de, Santos, C. C. G., Shibata, H. Y., Rocha, J. E. C. da, Pereira, A. A., Barros, C. do S. D., & Monteiro, C. P. S. (2022). Prevalence of the Human Immunodeficiency Virus and associated factors in pregnant women in the state of Pará. Revista Brasileira de Enfermagem, 75, e20210171. https://doi.org/10.1590/0034-7167-2021-0171

Reefhuis, J. (2020). Neural Tube Defects in Pregnancies Among Women With Diagnosed HIV Infection — 15 Jurisdictions, 2013–2017. MMWR. Morbidity and Mortality Weekly Report, 69. https://doi.org/10.15585/mmwr.mm6901a1

Reis, H. L. B., Boldrini, N. A. T., Rangel, A. F. R., Barros, V. F., Merçon de Vargas, P. R., & Miranda, A. E. (2020). Placental growth disorders and perinatal adverse outcomes in Brazilian HIV-infected pregnant women. PLOS ONE, 15(4), e0231938. https://doi.org/10.1371/journal.pone.0231938

Sara Rincón Franco, Uriel, M., Luis Martín Rodríguez, & Romero, C. (2020). Preventive measures to avoid vertical transmission in untreated pregnant women with HIV/AIDS. Case Reports, 13(3), e233426–e233426. https://doi.org/10.1136/bcr-2019-233426

Santana, A. Z. R., Reiners, A. A. O., Azevedo, R. C. de S., Silva, J. D. P., Andrade, A. C. S., & Mendes, P. A. (2021). Tendência temporal da incidência da AIDS em pessoas com 50 anos ou mais no Brasil*. Revista de Enfermagem Da UFSM, 11, e59. https://doi.org/10.5902/2179769263534

Silva, C. M., Alves, R. de S., Santos, T. S., Bragagnollo, G. R., Tavares, C. M., & Santos, A. A. P. (2018). Epidemiological overview of HIV/AIDS in pregnant women from a state of northeastern Brazil. Revista Brasileira de Enfermagem, 71(1), 568–576. https://doi.org/10.1590/0034-7167-2017-0495

Start Free Stay Free AIDS Free - 2020 report. (n.d.). Www.unaids.org. https://www.unaids.org/en/resources/documents/2020/start-free-stay-free-aids-free-2020-progress-report

Super-fast-track framework for ending aids among children, adolescents and young women by 2020. (n.d.). https://www.unaids.org/sites/default/files/media_asset/Stay_free_vision_mission_En.pdf

Tavares De Souza, M., Dias Da Silva, M., & De Carvalho, R. (2010). Revisão integrativa: o que é e como fazer Integrative review: what is it? How to do it? Einstein, 8(1), 102–108. https://www.scielo.br/j/eins/a/ZQTBkVJZqcWrTT34cXLjtBx/?format=pdf&lang=pt

Woldesenbet, S., Cheyip, M., Lombard, C., Manda, S., Ayalew, K., Kufa, T., & Puren, A. (2022). Progress towards the UNAIDS 95-95-95 targets among pregnant women in South Africa: Results from the 2017 and 2019 national Antenatal HIV Sentinel Surveys. PLOS ONE, 17(7), e0271564. https://doi.org/10.1371/journal.pone.0271564.

Downloads

Published

28/02/2024

How to Cite

LISBOA, A. C. L. .; REMOR, A. M. R. .; LOBATO, G. da S. .; PALHETA NETO, J. X. .; SANTANA, L. A. F. .; VIEIRA FILHO, L. L. B. .; HENRIQUES, N. B. . Complications generated by HIV/AIDS in pregnancy: An integrative review. Research, Society and Development, [S. l.], v. 13, n. 2, p. e12313245120, 2024. DOI: 10.33448/rsd-v13i2.45120. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/45120. Acesso em: 27 dec. 2024.

Issue

Vol. 13 No. 2

Section

Health Sciences

License

Copyright (c) 2024 Amanda Cunha Lima Lisboa; Amanda Maria Rodrigues Remor; Gabrielle da Silva Lobato; Job Xavier Palheta Neto; Lucas Andrey Ferreira Santana; Luis Levino Batista Vieira Filho; Niely Braga Henriques

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.