Updates on acute diverticulitis: Epidemiological, pathophysiological and clinical aspects
DOI:
https://doi.org/10.33448/rsd-v13i3.45198Keywords:
Diverticulitis; Abdominal pain; Epidemiology; Physiology.Abstract
Introduction: Acute diverticulitis is a prevalent condition that arises from the formation of diverticula in the intestinal colon, and their presence can be asymptomatic or symptomatic, and may or may not become inflamed throughout life. Therefore, the objective of this work is to discuss and present the most recent information about acute diverticulitis. Methodology: This is an integrative review about acute diverticulitis and its related aspects. Data from the Virtual Health Library (VHL), Scientific Electronic Library of Medicine (SciELO) and National Library of Medicine (PubMed) databases were used, by crossing the descriptors “diverticulitis”, “abdominal pain”, “epidemiology” and “physiology” to answer the question formulated through the PICO strategy. Results and Discussion: It is estimated that more than 50% and more than 60% of people aged 60 and 80, respectively, have diverticula in the colon, however, despite the relationship with age, young people have an increasing prevalence of acute diverticulitis. The mechanism behind the formation of diverticula is not specifically known and treatment is not yet standardized, with one of the main discussions being the use of antibiotics in uncomplicated acute diverticulitis. It is known that the clinical presentation of the uncomplicated acute form includes left abdominal pain, fever and malaise, leukocytosis may appear and, in case of complications, patients may develop perforation, peritonitis and other conditions. Conclusion: In view of the above, it is necessary to make people aware of the risk factors, as well as to produce larger studies so that a treatment can be defined and better standardized.
References
Bae, H. J., Kim, S. T., Hong, S. G., Lee, H., Choi, H. S., Cho, Y., Kim, T. H., & Chung, S. H. (2019). Risk Factors for Asymptomatic Colon Diverticulosis. The Korean Journal of Gastroenterology, 74(3), 142. https://doi.org/10.4166/kjg.2019.74.3.142
Cirocchi, R., Nascimbeni, R., Binda, G. A., Vettoretto, N., Cuomo, R., Gambassi, G., Amato, A., & Annibale, B. (2019). Surgical treatment of acute complicates diverticulitis in the elderly. Minerva Chirurgica. 74(6), 465-471. https://doi.org/10.23736/S0026-4733.18.07744-1
Qaseem, A., Etxeandia-Ikobaltzeta, I., Lin, J. S., Fitterman, N., Shamliyan, T., & Wilt, T. J. (2022). Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians. Annals of Internal Medicine, 175(3). https://doi.org/10.7326/m21-2710
Tursi, A., Scarpignato, C., Strate, L. L., Lanas, A., Kruis, W., Lahat, A., & Danese, S. (2020). Colonic diverticular disease. Nature Reviews Disease Primers, 6(1), 1–23. https://doi.org/10.1038/s41572-020-0153-5
Wan, D., & Krisko, T. (2021). Diverticulosis, Diverticulitis, and Diverticular Bleeding. Clinics in Geriatric Medicine, 37(1), 141–154. https://doi.org/10.1016/j.cger.2020.08.011
Ogino, T., Mizushima, T., Matsuda, C., Mori, M., & Yuichiro Doki. (2019). Essential updates 2018/2019: Colorectal (benign). Annals of Gastroenterological Surgery, 4(1), 30–38. https://doi.org/10.1002/ags3.12304
An, S. B., Kim, B. C., Kim, J. Y., Kim, J. W., & Lee, S.-J. (2019). Results of Laparotomy and Laparoscopy for Perforated Colonic Diverticulitis. JSLS: Journal of the Society of Laparoendoscopic Surgeons, 23(3), e2019.00007. https://doi.org/10.4293/jsls.2019.00007
Strate, L. L., & Morris, A. M. (2019). Epidemiology, Pathophysiology, and Treatment of Diverticulitis. Gastroenterology, 156(5), 1282–1298. https://doi.org/10.1053/j.gastro.2018.12.033
Turner, G. A., O’Grady, M. J., Purcell, R. V., & Frizelle, F. A. (2021). Acute Diverticulitis in Young Patients: A Review of the Changing Epidemiology and Etiology. Digestive Diseases and Sciences. https://doi.org/10.1007/s10620-021-06956-w
Reichert, M. C., Kupcinskas, J., Schulz, A., Schramm, C., Weber, S. N., Krawczyk, M., Jüngst, C., Casper, M., Grünhage, F., Appenrodt, B., Zimmer, V., Tamelis, A., Lukosiene, J. I., Pauziene, N., Kiudelis, G., Jonaitis, L., Goeser, T., Malinowski, M., Glanemann, M., & Kupcinskas, L. (2020). Common variation in FAM155A is associated with diverticulitis but not diverticulosis. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-58437-1
Nascimbeni, R., Amato, A., Cirocchi, R., Serventi, A., Laghi, A., Bellini, M., Tellan, G., Zago, M., Scarpignato, C., & Binda, G. A. (2020). Management of perforated diverticulitis with generalized peritonitis. A multidisciplinary review and position paper. Techniques in Coloproctology, 25(2), 153–165. https://doi.org/10.1007/s10151-020-02346-y
Souza, M. T. de, Silva, M. D. da, Carvalho, R de. (2012) Revisão integrativa: o que é e como fazer. Einstein. 8(1), 102–6.
Souza, M. T., Silva, M. D., & Carvalho, R. (2010). Integrative Review: What Is It? How to Do It? Einstein, 8(1), 102–106. https://doi.org/10.1590/s1679-45082010rw1134
Hawkins, A. T., Wise, P. E., Chan, T., Lee, J. T., Glyn, T., Wood, V., Eglinton, T., Frizelle, F., Khan, A., Hall, J., Ilyas, M. I. M., Michailidou, M., Nfonsam, V. N., Cowan, M. L., Williams, J., Steele, S. R., Alavi, K., Ellis, C. T., Collins, D., & Winter, D. C. (2020). Diverticulitis: An Update From the Age Old Paradigm. Current Problems in Surgery, 57(10), 100862. https://doi.org/10.1016/j.cpsurg.2020.100862
Rook, J. M., Dworsky, J. Q., Curran, T., Banerjee, S., & Kwaan, M. R. (2021). Elective surgical management of diverticulitis. Current Problems in Surgery, 58(5), 100876. https://doi.org/10.1016/j.cpsurg.2020.100876
Sartelli, M., Weber, D. G., Kluger, Y., Ansaloni, L., Coccolini, F., Abu-Zidan, F., Augustin, G., Ben-Ishay, O., Biffl, W. L., Bouliaris, K., Catena, R., Ceresoli, M., Chiara, O., Chiarugi, M., Coimbra, R., Cortese, F., Cui, Y., Damaskos, D., De' Angelis, G. L., Delibegovic, S., & Catena, F. (2020). 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World journal of emergency surgery: WJES, 15(1), 32. https://doi.org/10.1186/s13017-020-00313-4
Choe, E. K., Lee, J.-E., Chung, S. J., Yang, S. Y., Kim, Y. S., Shin, E.-S., Choi, S. H., & Bae, J. H. (2019). Genome-wide association study of right-sided colonic diverticulosis in a Korean population. Scientific Reports, 9, 7360. https://doi.org/10.1038/s41598-019-43692-8
Kim, Y. S. (2022). [Diagnosis and Treatment of Colonic Diverticular Disease]. The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi, 79(6), 233–243. https://doi.org/10.4166/kjg.2022.072
Dichman, M. L., & Shabanzadeh, D. M. (2021). Ugeskrift for laeger, 183(28), V01210081.
Francis, N. K., Sylla, P., Abou-Khalil, M., Arolfo, S., Berler, D., Curtis, N. J., Dolejs, S. C., Garfinkle, R., Gorter-Stam, M., Hashimoto, D. A., Hassinger, T. E., Molenaar, C. J. L., Pucher, P. H., Schuermans, V., Arezzo, A., Agresta, F., Antoniou, S. A., Arulampalam, T., Boutros, M., & Bouvy, N. (2019). EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice. Surgical Endoscopy, 33(9), 2726–2741. https://doi.org/10.1007/s00464-019-06882-z
Qaseem, A., Etxeandia-Ikobaltzeta, I., Lin, J. S., Fitterman, N., Shamliyan, T., & Wilt, T. J. (2022). Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians. Annals of Internal Medicine, 175(3), 416–431. https://doi.org/10.7326/m21-2711
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Gabriel de Carvalho Claudino; Luiz Otávio da Silva; Isabela Alves Campos Alcon; Gustavo Henrique Silva Souza; Camila Cornacchia; Manuela Silva da Costa; Michael Deslandes Bicalho Silva Araújo; Bruna Carvalho Duarte Sá; Rafaella Uzeloto de Oliveira; Bruno Pithon Costa Souza; Vitor Ávila de Oliveira; Álvaro Linhares Bandeira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.