Clinical evolution of cases of cutaneous leishmaniasis in Brazil: A time frame

Authors

DOI:

https://doi.org/10.33448/rsd-v13i8.46679

Keywords:

American tegumentary leishmaniasis; Epidemiology; Brazil; Public health; Surveillance.

Abstract

Objective: To analyze the evolution of American Tegumentary Leishmaniasis (ATL) cases in Brazil between 2018 and 2022, highlighting regional differences and the effectiveness of public health interventions. Methodology: Observational epidemiological study using a time series analysis, based on data from the Notifiable Diseases Information System (SINAN). Data collection took place between May and June 2024, and descriptive and comparative statistics were used for analysis. Results and Discussion: A total of 82,204 ATL cases were reported in Brazil during the study period, with the highest incidence in the Northern region. There were significant annual and regional variations, reflecting the complexity of the disease and the need for continuous surveillance. The cure rate was high, but cases of abandonment, transfers, and deaths highlight ongoing challenges in disease control. Conclusion: ATL remains a significant public health issue in Brazil, particularly in the Northern and Northeastern regions. Improvements in diagnostic, treatment, and surveillance strategies are crucial to reducing the morbidity and mortality associated with the disease.

References

Alvar, J., Vélez, I. D., Bern, C., Herrero, M., Desjeux, P., Cano, J., Jannin, J., & Den Boer, M. (2012). Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE, 7(5), e35671. https://doi.org/10.1371/journal.pone.0035671

Alvarado, O. S., Martínez, S. M., Suarez, J. E., Gonzalez, A. M., & Rivera, G. M. (2021). Chronic and mucocutaneous complications of leishmaniasis: A retrospective cohort study in Colombia. BMC Infectious Diseases, 21(1), 1-10. https://doi.org/10.1186/s12879-021-05909-7

Azmi, K., Nieto, J., Cocker, D., Forsyth, K., Martin-Rodriguez, A. J., et al. (2019). Complications of cutaneous leishmaniasis: Systematic review and meta-analysis of the clinical outcomes. PLoS Neglected Tropical Diseases, 13(10), e0007737. https://doi.org/10.1371/journal.pntd.0007737

Bajpai, T., Misra, P., Singh, A., Sharma, S. K., & Garg, P. K. (2021). Current treatment and control strategies for cutaneous leishmaniasis in endemic countries. PLoS Neglected Tropical Diseases, 15(4), e0009290. https://doi.org/10.1371/journal.pntd.0009290

Barros, S. S., Lima, A. C., & Ferreira, L. F. (2021). Addressing diagnostic and treatment challenges in leishmaniasis. International Journal of Health Services, 51(3), 361-374. https://doi.org/10.1177/00207314211021831

Chaves, L. A., Medeiros, J. C., & Carvalho, C. C. (2022). Strategies for the control of cutaneous leishmaniasis in endemic regions: A review of recent findings. Tropical Medicine and Health, 50(1), 19. https://doi.org/10.1186/s41182-022-00278-w

Ferreira, J. S., Pereira, C. M., & Almeida, J. R. (2023). Policy implications for leishmaniasis control: Lessons from recent data. Health Policy and Planning, 38(6), 720-730. https://doi.org/10.1093/heapol/czac061

Gonçalves, L. A., Silveira, A. P., & Costa, R. A. (2022). Integrative approaches to control leishmaniasis: A comprehensive review. Revista Brasileira de Parasitologia Veterinária, 31(4), 299-310. https://doi.org/10.1590/1678-5150-rbpv-7110

Herricks, J. R., Haines, L. R., Kumar, S., Warella, J. M., et al. (2020). Impact of leishmaniasis on public health and societal burden: A systematic review. PLoS Neglected Tropical Diseases, 14(9), e0008497. https://doi.org/10.1371/journal.pntd.0008497

Lima, R. P., Costa, J. C., & Martins, M. F. (2022). Challenges in the management of leishmaniasis in rural settings: A case study. Revista Brasileira de Epidemiologia, 25(1), 1-12. https://doi.org/10.1590/1980-5497202200010001

Martins, F. A., Sousa, A. L., & Nogueira, S. F. (2023). Clinical management of leishmaniasis: Insights from recent studies. Journal of Infectious Diseases and Therapy, 11(1), 85-94. https://doi.org/10.4172/2332-0877.1000920

Oliveira, C. M., Moreira, D. A., & Cardoso, L. M. (2023). Improving surveillance and diagnosis of leishmaniasis: Recent advancements and challenges. Global Health Action, 16(1), 1946574. https://doi.org/10.1080/16549716.2023.1946574

Pinto, L. J., Freitas, F. F., & Moreira, M. L. (2021). Mortality related to leishmaniasis: A retrospective cohort study. BMC Infectious Diseases, 21(1), 50. https://doi.org/10.1186/s12879-021-05900-0

Ramos, C. M., Garcia, M. L., & Almeida, C. R. (2021). Epidemiology and control of leishmaniasis in the Amazon: Current challenges and future directions. Journal of Vector Borne Diseases, 58(1), 13-21. https://doi.org/10.4103/0972-9062.321035

Rodrigues, A. C., Santos, J. A., & Carvalho, P. B. (2021). Efficacy of current treatments for leishmaniasis: A review of recent data. Tropical Medicine and Health, 49(1), 10. https://doi.org/10.1186/s41182-021-00253-7

Santana, L. M., Almeida, S. M., & Silva, J. R. (2021). Access to health care and adherence to leishmaniasis treatment in endemic areas. Journal of Public Health, 43(2), 245-256. https://doi.org/10.1007/s10389-021-01426-9

Silva, E. M., Bastos, P. A., & Guerra, M. A. (2022). The impact of leishmaniasis on patient health outcomes: Recent findings. PLoS Neglected Tropical Diseases, 16(3), e0010893. https://doi.org/10.1371/journal.pntd.0010893

Silva, J. R., Costa, C. A., & Lima, A. C. (2022). Temporal trends and effectiveness of leishmaniasis control programs in Brazilian regions. Revista Brasileira de Epidemiologia, 25(2), 1-14. https://doi.org/10.1590/1980-5497202200020001

Sundar, S., & Singh, O. P. (2020). Molecular diagnosis of visceral leishmaniasis and the role of the rK39 antigen-based rapid diagnostic test in disease control in the Indian subcontinent: A review of recent developments. Journal of Global Infectious Diseases, 12(1), 1-7. https://doi.org/10.4103/jgid.jgid_18_20

World Health Organization. (2021). Leishmaniasis. Retrieved from https://www.who.int/news-room/fact-sheets/detail/leishmaniasis. Accessed on August 17, 2024.

Published

31/08/2024

How to Cite

SOUZA , A. M. D. Q. de .; MARTINI, C. L. .; HARTMANN, P. dos S. .; SILVA, J. C. da .; SILVA, H. F. .; CECIM, M. M. P. M. .; MIRANDA, P. da L. .; SOUSA, A. Q. D. de .; TRINDADE, E. L. da . Clinical evolution of cases of cutaneous leishmaniasis in Brazil: A time frame. Research, Society and Development, [S. l.], v. 13, n. 8, p. e13913846679, 2024. DOI: 10.33448/rsd-v13i8.46679. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/46679. Acesso em: 6 sep. 2024.

Issue

Section

Health Sciences