Applicability of Rosemary (Rosmarinus officinalis) as a potential herbal medicine in Dentistry: a literature review
DOI:
https://doi.org/10.33448/rsd-v9i7.4767Keywords:
Phytotherapy; Rosmarinus; Dentistry; Dental plaque.Abstract
There is a constant search for drugs to fight infections effectively. Herbal medicines are presented as options that, in addition to having great therapeutic potential, generally have low cost. Literature data show that rosemary (Rosmarinus officinalis) has antimicrobial activity. Thus, the objective of this work was, through the existing literature, to verify whether R. officinalis has therapeutic and antimicrobial properties in pathological conditions of the oral cavity, and can be used for treatments of mouth infections. In the present review, the databases used for screening were: Scientific Eletronic Library Online (SCIELO) and PubMED, using the following descriptors: "Rosemary" "Rosmarinus officinalis", "Antimicrobial action", "application in Dentistry", “Phytotherapy in Dentistry”, isolated or in combination, in Portuguese and English. The studies were analyzed according to the year of publication, publication period and results found. Among the researches evaluated, only 3 did not show significant results regarding their antimicrobial action. In other studies, it was found to be effective against fungi, bacteria, viral agents and to inhibit the formation of oral biofilms. Thus, the literature points to the effectiveness of R. officinalis as an antimicrobial in relation to fungi and pathogenic bacteria in the mouth, having a clinical application in the treatment and prevention of diseases of the oral cavity.
References
Barbosa, LN, Probst, IS, Andrade, BT, Alves, FB, Albano, M, Cunha, ML, Doyama, JT, Rall, VLM & Fernandes Júnior, A. (2015). In vitro Antibacterial and Chemical Properties of Essential Oils Including Native Plants from Brazil against Pathogenic and Resistant Bacteria. Journal of Oleo Science, 64(3):289–298.
Bernardes, WA, Lucarinia, R, Tozatti, MG, Flauzino, LGB, Souza, MGM, Turatti, ICC, et al. (2010). Antibacterial Activity of the Essential Oil from Rosmarinus officinalis and its Major Components against Oral Pathogens. Verlag der Zeitschriftfür Naturforschung, 65: 588-593.
Bestagno, V, Neira, I, Gaete, PG, Pastene, E, Gómez, M, Pérez, MA et al. (2017). Estudio del efecto de um enjuagatorio de Rosmarinus officinalis (romero) em la cicatrización de heridas de mucosa oral, Int. j. odontostomatol, 11(4):411-417.
Brasil. Ministério da Saúde. Portaria n°886 (20, maio, 2010). Institui, no âmbito do Sistema Único de Saúde - SUS, sob gestão estadual, municipal ou do Distrito Federal, a Farmácia Viva. Diário Oficial da União, Brasília-DF, 22 de abr. p.75, 2010
Cáceres, M, Hidalgo, W, Stashenko, E, Torres, R & Claudia Ortiz, C. (2020). Essential Oils of Aromatic Plants with Antibacterial, Anti-Biofilm and Anti-Quorum Sensing Activities against Pathogenic Bacteria. Journal of Antibiotics, 9:147.
Castro RD & Lima, EO. (2011). Atividade antifúngica dos óleos essenciais de sassafrás (Ocotea odorifera Vell.) e alecrim (Rosmarinus officinalis L.) sobre o gênero Candida, Revista Brasileira de Plantas Medicinais, 13 (2), 203-208.
Ferreira-Filho, JCC, Gondim, BLC, Cunha, DA, Figueiredo, CC & Valença, AMG. (2014). Physical properties and antibacterial activity of herbal tinctures of Calendula (Calendula officinalis L.) and Cashew Tree (Anacardium occidentale L.). Pesqui Bras Odontopediatria Clin Integr, 14(1), 49-53.
Filho, JCCF, Ribeiro, ILA, Martins, JM, Borges, LP & Valença, AMG. (2015). Ação antibacteriana de Rosmarinus officinalis L. e Maytenusilicifolia Mart. Sobre bactérias orais. Revista da Faculdade de Odontologia, Passo Fundo, 20(3):313-318.
Francisco, KSF. (2010). Fitoterapia: uma opção para o tratamento odontológico. Rev. saúde. 4(1), 18-24.
Gauch, LMR, Gomes, FS, Esteves, RA, Pedrosa, SS, Gurgel, ESC, Arruda, AC, et al. (2014). Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Rev Soc Bras Med Trop, 47(3):389-391.
Gauch, LMR, Gomes, FS, Esteves, RA, Pedrosa, SS, Gurgel, ESC, Arruda, AC et al. (2014). Antifungal activity of Rosmarinus officinalis Linn. essential oil against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida krusei. Rev Pan-Amaz Saude; 5(1):61-66.
Gouveia, CL, Freire, ICM, Leite, MLAS, Figueiredo, RDA, Almeida, LFD, Cavalcante, YW, et al. (2014). Antifungal activity of components used for decontamination of dental prostheses on the growth of Candida albicans. Rev Odontol UNESP, 43(2):137-143.
Hickl, J, Argyropoulou, A, Sakavitsi, ME, Halabalaki, M, Ahmad, AA, Hellwig, E, et al. (2018). Mediterranean herb extracts inhibit microbial growth of representative oral microorganisms and biofilm formation of Streptococcus mutans. PLOS ONE, 13(12): 1-24.
Jardim, EGJ, Merino, VRC & Campos, MJA. (2015). Aspectos Microbiológicos de Infecções Bucais: Relação Ecológica e de Virulência. Laboratório de Anaeróbios. Departamento de Microbiologia. Instituto de Ciências Biomédicas. Universidade de São Paulo, São Paulo.
Leal, ACL, Palou, E, Malo, AL & Bach, H. (2019). Antimicrobial, cytotoxic and anti-inflammatory activities of Pimentadioicaand Rosmarinus officinalis essential oils. Biomed Res Int, 2019:1-9.
Manilal, A, Sabu, KR, Shewangizaw, M, Aklilu, A, Seid, M, Merdekios, B, et al. (2020). In vitro antibacterial activity of medicinal plants against biofilm-forming methicillin-resistant Staphylococcus aureus: efficacy of Moringa stenopetala and Rosmarinus officinalis extracts. Heliyon. 6, 33- 40.
Monteiro, MH & Fraga, S. (2016). Fitoterapia na odontologia: levantamento dos principais produtos de origem vegetal para saúde bucal. Revista Fitos, 9(4), 265-268.
Nakagawa, S, Hillebrand, GG & Nunez, G. (2020). Rosmarinus officinalis L. (Rosemary) Extracts Containing Carnosic Acid and Carnosol are Potent Quorum Sensing Inhibitors of Staphylococcus aureus Virulence. Journal of Antibiotics, 9:149.
Nakagawa, S, Hillebrand, GG & Nunez, G. (2020). Rosmarinus officinalis L. (Rosemary) extracts containing canosic acid and carnosol are potent quorum sesing inhibitors of Staphylococcus aureus virulence. Antibiotics (Basel), 9(149),1-11.
Oliveira, JR, Melo, GFS, Camargo, SEA, Vasconcellos, LMR & Oliveira, LD. (2019). Total protein level reduction of odonto pathogens biofilms by Rosmarinus officinalis L. extract: an analysis on Candida albicans and Streptococcus mutans. Braz Dent Sci, 22(2): 260-266.
Oliveira. JR, Camargo, SEA & Oliveira LD. (2019). Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. J Biomed Sci, 26(5):1-22.
Pereira, AC, Dias, AA, Vazquez, FL, Salomão, FGD, Cortellazzi, KL, Meneghim, M, et al. (2013). Saúde coletiva: métodos preventivos para doenças bucais. São Paulo: Artes Médicas Ltda.; 2013, 1-10.
Pereira, SLS, Praxedes, YCM, Bastos, TC, Alencar, PNB & Costa, FN. (2013). Clinical effect of a gel containing Lippiasidoides on plaque and gingivitis control. Eur J Dent, 7:28-34.
Rahnama, M, Fakheri, BA, Mashhady, MA & Saeidi, S. (2019). Anti-Bacterial and Anti-Biofilm Activity of Glycyrrhiza glabra, Rosmarinus officinalis and Saponaria officinalis Extracts on Important Food Pathogens. Gene, Cell and Tissue, 6 (4), 963-976.
Sepehri, Z, Javadian, F, Khammari, D & Hassanshahian, M. (2016). Antifungal effects of the aqueous and ethanolic leaf extracts of Echinophora platyloba and Rosmarinus officinalis. Curr Med Mycol, 2(1):30-35.
Silva, S, Alves, N, Silva, P, Vieira, T, Maciel, P, Castellano, LR, et al. (2019). Antibacterial activity of Rosmarinus officinali, Zingiber officinale, Citrus aurantium bergamia, and Copaifera officinalis alone and in combination with calcium hydroxide against Enterococcus faecalis. Biomed Res Int, 2019:1-7
Valones, MAA, Higino, JS, Souza, PRE, Crovella, S, Júnior, AFC & Carvalho, AAT. (2016). Dentifrice containing extract of Rosmarinus officinalis linn: an antimicrobial evaluation. Braz Dent J. 27(5):497-501.
Valones, MAA, Silva, ICG, Gueiros, LAM, Leão, JC, Jr, AFC & Carvalho, AAT. (2019). Clinical assessment of rosemary based toothpaste (Rosmarinus officinalis Lin.): a randomized controlled double-blind study. Braz Dent J, 30(2):146-151
.
World Health Organization [página na internet]. Traditional, complementary and integrative medicine [acesso em 17 de abril de 2020]. Disponível em: https://www.who.int/health-topics/traditional-complementary-and-integrative-medicine#tab=tab_1.
Yoo, MS, Jin, HJ & Lee, SY. (2020). Synergistic antibacterial efficacies of chlorhexidine digluconate of protamine sulfate combined with Laminaria japonica or Rosmarinus officinalis extracts against Streptococcus mutans. Biocontrol Sci, 25(1):41-44.
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