Corticoid-induced myopathy in a patient with Sjögren's Syndrome: Case report and literature review
DOI:
https://doi.org/10.33448/rsd-v13i12.47828Keywords:
Miopatia; Glicocorticoides; Corticosteroids.Abstract
Glucocorticoid-induced myopathy is a toxic disease caused by the exogenous administration of these drugs, either orally or intravenously. Clinically, it is characterized by weakness and low endurance of the skeletal muscles. The aim of this article is to inform readers about how the prolonged use of corticosteroids can lead to the onset of myopathy, identifying how this affects the patient's quality of life. The present study reports the case of a patient diagnosed with Sjögren's Syndrome who presented complications of her pathology, necessitating the use of corticosteroids. Following the administration of the medication, the patient developed muscle weakness in the lower limbs. Based on the association between the clinical presentation, laboratory tests, and electroneuromyography, the main diagnostic hypothesis for the reported patient was corticosteroid-induced myopathy.
References
Blaauw, B., & Reggiani, C. (2014). O papel das células satélites na hipertrofia muscular. Journal of Muscle Research and Cell Motility, 35(1), 3–10.
Carstens, P.-O., & Schmidt, J. (2014). Diagnosis, pathogenesis and treatment of myositis: recent advances. Clinical & Experimental Immunology, 175(3), 349–358.
Carvalho, F. N., Dias, R. J. S., & Carneiro, A. P. (2004). Steroid myopathy. Acta Fisiátrica.
Cecin, H. A., & Ximenes, A. C. (2015). Tratado Brasileiro de Reumatologia. Editora Atheneu.
Costa, S. A. (2020). Abordagem terapêutica na dermatomiosite (Tese de Doutorado).
Coutinho, A., et al. (2023). Corticosteroid-induced myopathy. Cureus, 15(11), e49548.
Dirks-Naylor, A. J., & Griffiths, C. L. (2009). Glucocorticoid-induced apoptosis and cellular mechanisms of myopathy. Journal of Steroid Biochemistry and Molecular Biology, 117(1-3), 1-7. https://doi.org/10.1016/j.jsbmb.2009.05.014
Foye, P. M. (n.d.). Corticosteroid-Induced Myopathy: Practice Essentials, Pathophysiology, Epidemiology.
Gupta, Y., & Gupta, A. (2013). Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment. Indian Journal of Endocrinology and Metabolism, 17(5), 913.
Hardy, R. S., Raza, K., & Cooper, M. S. (2020). Therapeutic glucocorticoids: mechanisms of actions in rheumatic diseases. Nature Reviews Rheumatology, 16(3), 133–144.
Iftikhar, A., et al. (2021). Cancer and stress: Does it make a difference to the patient when these two challenges collide? Cancers, 13(2), E163.
Lameira, I. M. (2024). Síndrome de Sjögren em homens: revisão sistemática da literatura sobre os aspectos clínicos, complicações e abordagens terapêuticas.
Martins, L., et al. (2020). Mielite transversa aguda: revisão de literatura. Brazilian Journal of Surgery & Clinical Research, 30(3).
Miernik, S., Matusiewicz, A., & Olesinka, M. (2024). Drug-induced myopathies: A comprehensive review and update. Biomedicines, 12(5), 987.
Mo, C., et al. (2019). Steroid myopathy: Understanding the pathogenesis (PhD Thesis).
Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Editora UAB/NTE/UFSM.
Satoshi, D., et al. (2023). As miopatias inflamatórias no contexto da pesquisa brasileira: uma revisão de escopo. Jornal de Assistência Farmacêutica e Farmacoeconomia, 8(s2).
Schakman, O., et al. (2013). Glucocorticoid-induced skeletal muscle atrophy. The International Journal of Biochemistry & Cell Biology, 45(10), 2163–2172.
Silva, R. H. (2009). Avaliação de proteção celular a isquemia de retalhos musculares com soluções preservadoras de tecidos em modelo de ratos (Tese de Mestrado).
Surmachevska, N., & Tiwari, V. (2020). Corticosteroid-induced myopathy.
Surmachevska, N., & Tiwari, V. (2023). Miopatia induzida por corticoides. In StatPearls. Treasure Island (FL): StatPearls Publishing.
Toassi, R. F. C. & Petry, P. C. (2021). Metodologia científica aplicada à área da Saúde. (2. ed.) Editora da UFRGS.
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