Microplásticos y salud humana: Un análisis cienciométrico
DOI:
https://doi.org/10.33448/rsd-v14i5.48749Palabras clave:
Contaminación plástica; Cienciometría; Producción científica; Salud pública; Presencia de microplásticos.Resumen
La acumulación de plásticos se puede observar macroscópicamente, en las pilas de botellas y bolsas de plástico en los vertederos, y de manera menos visible, microscópicamente, a través de los microplásticos. Nuestro objetivo principal fue evaluar la producción científica sobre microplásticos y salud humana utilizando la base de datos Web of Science. Nos enfocamos en estimar el número de publicaciones por año, los países más relevantes en número de publicaciones, las colaboraciones destacadas con otros países, los artículos más citados, las revistas más relevantes y el enfoque de los estudios. Setenta y dos países presentaron investigaciones científicas sobre microplásticos y salud, destacando la importancia mundial del tema. Las publicaciones comenzaron en países europeos y más recientemente en países asiáticos. Autores de China publicaron el mayor número de artículos, pero los más citados son de países europeos cuyos autores fueron los primeros en publicar sobre el tema. La revista que ocupó el primer lugar en relevancia fue Science of the Total Environment, que aborda diversos aspectos relacionados con la cuestión de los microplásticos y la salud humana. En cuanto al enfoque de los estudios, la categoría "microplásticos en los alimentos" fue la que presentó el mayor número de publicaciones. A partir del panorama trazado por nuestro análisis cienciométrico, se destaca un aumento significativo de publicaciones en los últimos años, se identifican brechas y se sugieren formas de mejorar la investigación sobre la salud humana y los microplásticos.
Citas
Amato-Lourenço, L. F., Carvalho-Oliveira, R., Júnior, G. R., dos Santos Galvão, L., Ando, R. A., & Mauad, T. (2021). Presence of airborne microplastics in human lung tissue. Journal of Hazardous Materials, 416, 126124. https://doi: 10.1016/j.jhazmat.2021.126124.
Aria, M., & Cuccurullo, C. (2017). bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics, 11(4), 959–75. https:// doi.org/10.1016/j.joi.2017.08.007.
Barboza, L. G. A., Dick Vethaak, A., Lavorante, B. R. B. O., Lundebye, A. K., & Guilhermino, L. (2018). Marine microplastic debris: An emerging issue for food security, food safety and human health. Marine Pollution Bulletin, 133(0025-326X), 336–48. https://doi.org/10.1016/j.marpolbul.2018.05.047.
Brainard, J., & Normile, D. (2022). China rises to first place in one key metric of research impact. Science, 377(6608), 799–9. https://doi: 10.1126/science.ade4423.
Carbery, M., O’Connor, W., & Palanisami, T. (2018). Trophic transfer of microplastics and mixed contaminants in the marine food web and implications for human health. Environment International, 115, 400–9. https://doi.org/10.1016/j.envint.2018.03.007.
Carrington, D. (2024). Microplastics found in every human placenta tested in study. https://www.theguardian.com/environment/2024/feb/27/microplastics-found-every-human-placenta-tested-study-health-impact.
Chen, H., Xu, L., Yu, K., Wei, F., & Zhang, M. (2023). Release of microplastics from disposable cups in daily use. Science of The Total Environment. 854, 158606. https://doi.org/10.1016/j.scitotenv.2022.158606.
Cox, K. D., Covernton, G. A., Davies. H. L., Dower, J. F., Juanes, F, & Dudas, S. E. (2019). Human Consumption of Microplastics. Environmental Science & Technology, 53(12), 7068–74. https://doi.org/10.1021/acs.est.9b01517
Damaj, S, Trad. F., Goevert, D., & Wilkesmann, J. (2024). Bridging the Gaps between Microplastics and Human Health. Microplastics, 3(1), 46–66. https://doi:10.20944/preprints202309.0288.v1
Danso, I. K., Woo J. H., & Lee K. (2022). Pulmonary Toxicity of Polystyrene, Polypropylene, and Polyvinyl Chloride Microplastics in Mice. Molecules, 27(22), 7926. http//: doi.org/10.3390/molecules27227926.
Dris, R., Gasperi, J., Mirande., C., Mandin, C., Guerrouache, M., Langlois, V & Tassin, B. (2017). A first overview of textile fibers, including microplastics, in indoor and outdoor environments. Environmental Pollution, 221, 453–8. www.http://doi.org/10.1016/j.envpol.2016.12.013.
Gao, Y., Ge, L., Shi, S., Sun, Y., Liu. M, Wang B, Shang, Y., Wu, J. & Tian, J. (2019). Global trends and future prospects of e-waste research: a bibliometric analysis. Environmental Science and Pollution Research, 26(17),17809–20. www.http://doi.org/10.1007/s11356-019-05071-8.
Hauptman, P. J. (2016). Impact or Impact Factor? Journal of Cardiac Failure, 22(10), 751-52. www.http://doi.org/10.1016/j.cardfail.2016.08.004
Ho, Y. W., Lim, J. Y., Yeoh, Y. K., Chiou, J. C., Zhu, Y., Keng, P. L., Li, L., & Chan, P. K. S. (2022). Preliminary Findings of the High Quantity of Microplastics in Faeces of Hong Kong Residents. Toxics, 10(8), 414–4. www.http://doi: 10.3390/toxics10080414
Hossain, S., Rahman, M. A., Ahmed, C. M., & Kumar, M. S. (2020). Plastic pollution in Bangladesh: A review on current status emphasizing the impacts on environment and public health. Environmental Engineering Research, 26(6). www.http://doi.org/10.4491/eer.2020.535
INMETRO. (2018). Inspetores e Auditoria de Estudos com foco In vitro. http://www.inmetro.gov.br/credenciamento/eventos-cgcre/Inspetores-BPL/Inspecao_e_Auditoria_de_Estudos_com_Foco_em_In_vitro.pdf.
Ramia, J. M. (2023). How to select a journal for your research. World Journal of Gastroenterology, 29 (21), 3379–84. www.http://doi: 10.3748/wjg.v29.i21.3379
Park, J. H., Hong, S., Kim, O. H., Kim, C. H., Kim, J., Kim, J. W., Hong, S., & Lee, H. J. (2023). Polypropylene microplastics promote metastatic features in human breast cancer. Scientific Reports, 13(1), 6252. www.http://doi: 10.1038/s41598-023-33393-8
Kacprzak, S. & Tijing, L. D. (2022). Microplastics in indoor environment: Sources, mitigation and fate. Journal of Environmental Chemical Engineering, 10(2),107359. www.http://doi.org/10.1016/j.jece.2022.107359.
Kadac-Czapska, K., Knez, E., Gierszewska, M., Olewnik-Kruszkowska, E., & Grembecka, M. (2023). Microplastics Derived from Food Packaging Waste—Their Origin and Health Risks. Materials, 16(2), 674. www.http://doi: 10.3390/ma16020674.
Koelmans, A. A., Mohamed Nor, N. H., Hermsen, E., Kooi, M., Mintenig, S. M., & De France, J. (2019). Microplastics in freshwaters and drinking water: Critical review and assessment of data quality. Water Research, 155(1), 410–22. www.http://doi.org/10.1016/j.watres.2019.02.054
Krishnan, K. (2023). A Systematic Review on the Impact of Micro-Nanoplastics Exposure on Human Health and Diseases. Biointerface Research in Applied Chemistry,13(4), 381. www.http://doi.org/10.33263/BRIAC134.381.
Kutralam-Muniasamy, G., Pérez-Guevara, F., Elizalde-Martínez, I., & Shruti, V. C. (2020). Review of current trends, advances and analytical challenges for microplastics contamination in Latin America. Environmental Pollution, 267, 115463. https://doi.org/10.1016/j.envpol.2020.115463
Kwon, J. H., Kim, J. W., Pham, T. D., Tarafdar, A., Hong, S., Chun, S. H., Lee, S. H., Kang, Da.Y. K., Kim, J. Y, Kim, S. B., & Jung, J. (2020). Microplastics in Food: A Review on Analytical Methods and Challenges. International Journal of Environmental Research and Public Health, 17(18), 6710. https://doi.org/10.3390/ijerph17186710
Lattu, A. (2023). Open Science in China: An Open and Closed Case. https://www.mpiwg-berlin.mpg.de/observations/open-science-china
Lang, I. A., Galloway, T. S., Scarlett, A., Henley, W. E., Depledge, M., Wallace, R. B., & Melzer, D. (2008). Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults. Jama, 300(11), 1303-1310. https://doi:10.1001/jama.300.11.1303
Leslie, H. A., van Velzen, J. M.M., Brandsma, S. H., Vethaak, D., Garcia-Vallejo, J. J., & Lamoree, M. H. (2022). Discovery and quantification of plastic particle pollution in human blood. Environment International, 163(107199), 107199. https:// doi.org/10.1016/j.envint.2022.107199
Li, M., Wang, Y., Xue, H., Wu, L., Wang, Y., Wang, C., Gao, X., Li, Z., Zhang, X., Hasan, M., Alruqi, M., Bokhari, A., & Han, N. (2022). Scientometric analysis and scientific trends on microplastics research. Chemosphere, 304,135337. https:// doi.org/10.1016/j.chemosphere.2022.135337
Li, S., Keenan, J.I., Shaw,I. C., & Frizelle, F. A. (2023). Could Microplastics Be a Driver for Early Onset Colorectal Cancer? Cancers, 15(13), 3323. https://doi: 10.3390/cancers15133323
Liu, Q., Chen, Z., Chen, Y., Yang, F., Yao, W., & Xie, Y. (2022). Microplastics contamination in eggs: Detection, occurrence and status. Food Chemistry, 397, 133771. www.http://doi.org/10.1016/j.foodchem.2022.133771
Liu, S., Guo, J., Liu, X., Yang, R., Wang, H., Sun, Y, Chen, B., & Dong, R. (2023). Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: A pilot prospective study. Science of The Total Environment, 854 (158699), 158699. www.http://doi: 10.1016/j.scitotenv.2022.158699
Macias-Chapula, C. A. (1998). O papel da informetria e da cienciometria e sua perspectiva nacional e internacional. Ciência da Informação, 27(2). www.http://doi.org/10.1590/S0100-19651998000200005
Makhdoumi, P., Pirsaheb, M., Amin, A. A., Kianpour, S., & Hossini, H. (2023). Microplastic pollution in table salt and sugar: Occurrence, qualification and quantification and risk assessment. Journal of Food Composition and Analysis, 119, 105261. www.http://doi.org/10.1016/j.jfca.2023.105261.
Ministério da Saúde (2019). Guia alimentar para crianças brasileiras menores de 2 anos. http://189.28.128.100/dab/docs/portaldab/publicacoes/guia_da_crianca_2019.pdf
Montano, L, Giorgini, E., Notarstefano, V., Notari, T., Ricciardi, M., Piscopo, M., & Motta, O. (2023). Raman Microspectroscopy evidence of microplastics in human semen. Science of The Total Environment, 901,165922. http://doi: 10.1016/j.scitotenv.2023.165922.
Munari, C., Infantini, V., Scoponi, M., Rastelli, E., Corinaldesi, C., & Mistri, M. (2017). Microplastics in the sediments of Terra Nova Bay (Ross Sea, Antarctica). Marine Pollution Bulletin, 122(1-2),161–5. www.http://doi: 10.1016/j.marpolbul.2017.06.039
Napper, I. E., Davies, B. F. R., Clifford, H., Elvin, S., Koldewey, H. J., Mayewski, P. A., Miner, K. R., Potocki, M., Elmore, A. C., Gajurel, A. P., & Thompson, R. C. (2020). Reaching New Heights in Plastic Pollution—Preliminary Findings of Microplastics on Mount Everest. One Earth, 3(5),621–30. http://doi.org/10.1016/j.oneear.2020.10.020
OECD. (2007). OECD Reviews of Innovation Policy China: Synthesis Report. OECD Publishing, Paris. . https://www.oecd.org/en/publications/oecd-reviews-of-innovation-policy-china_9789264039643-en.html
Park, J. H., Hong, S., Kim, O. H., Kim, C. H., Kim, J., Kim, J. W., et al. (2023). Polypropylene microplastics promote metastatic features in human breast cancer. Scientific reports, 13(1), 6252.
Patil, P. B., Maity, S., & Sarkar, A. (2022). Potential human health risk assessment of microplastic exposure: current scenario and future perspectives. Environmental Monitoring and Assessment, 194(12). http://doi: 10.1007/s10661-022-10539-1.
Peng, X., Chen, M., Chen, S., Dasgupta, S., Xu, H., Ta, K., Du, M., Lil, Z., Guo, Z., & Bai, S. (2018). Microplastics contaminate the deepest part of the world’s ocean. Geochemical Perspectives, 9 (1),1-5. https://doi: 10.7185/geochemlet.1829
Pironti, C., Notarstefano, V., Ricciardi, M., Motta, O., Giorgini, E., & Montano, L. (2022). First evidence of Microplastics in Human Urine, a Preliminary Study of Intake in the Human Body. Toxics, 11(1),40. https://doi: 10.3390/toxics11010040.
Prata, J. C., da Costa, J. P., Lopes, I., Duarte, A. C., & Rocha-Santos, T. (2020). Environmental exposure to microplastics: An overview on possible human health effects. Science of The Total Environment, 702 (134455). http://doi.org/10.1016/j.scitotenv.2019.134455
Prata, J. C. (2018). Airborne microplastics: Consequences to human health? Environmental Pollution, , 234, 115–26. https://doi: 10.1016/j.envpol.2017.11.043
Ragusa, A., Notarstefano, V., Svelato, A., Belloni, A., Gioacchini, G., Blondeel, C., Zucchelli, E. De Luca, C., DAvino, S., Gulotta, A. Carnevali, O. & Giorgini, E. (2022). Raman Microspectroscopy Detection and Characterisation of Microplastics in Human Breastmilk. Polymers,14(13),2700. https://doi.org/10.3390/polym14132700
Ragusa, A., Svelato, A., Santacroce, C., Catalano, P., Notarstefano, V., Carnevali. O., Papa, F., Rongioletti, M. C. A., Baiocco, F., Draghi, S. D’Amore E., Rinaldo, D. Matta. M., & Giorgi, E. (2021) Plasticenta: First evidence of microplastics in human placenta. Environment International ,146(106274), 106274. https://doi.org/10.1016/j.envint.2020.106274.
Rochman, C. M., Tahir, A., Williams, S. L., Baxa. D., Lam, R., Miller, J. T., Foo- Ching, T. Werorilangi, S. & Teh, J. S. (2015). Anthropogenic debris in seafood: Plastic debris and fibers from textiles in fish and bivalves sold for human consumption. Scientific Reports, (1), 1-10. https://doi:10.1038/srep14340.
Rodríguez, Y. E. (2007) Ética de la Investigación en Modelos Animales de Enfermedades Humanas. Acta bioethica, 13(1), 25–40. https://doi.org/10.4067/S1726-569X2007000100004
Rowley, J., Sbaffi, L., Sugden, M., & Gilbert, A. (2020). Factors influencing researchers’ journal selection decisions. Journal of Information Science, 48(3), 321-35.https://doi.org/10.1177/0165551520958
Schirinzi, G. F., Pérez-Pomeda, I., Sanchís, J., Rossini, C., Farré, M., & Barceló, D. (2017). Cytotoxic effects of commonly used nanomaterials and microplastics on cerebral and epithelial human cells. Environmental Research, 159, 579–87.https:// doi: 10.1016/j.envres.2017.08.043
Schwabl, P., Köppel, S, Königshofer, P., Bucsics, T., Trauner, M., Reiberger, T., & Liebmann, B. (2019). Detection of Various Microplastics in Human Stool. Annals of Internal Medicine, 171(7),453. https://doi.org/10.7326/M19-0618
Sharma, D, Jaiswal, S., & Kaur, G. (2022). Scientometric analysis and identification of research trends in microplastic research for 2011–2019. Environmental Science and Pollution Research, (29), 84312–84324. https://doi.org/10.1007/s11356-022-20872-0
Singh, A. K., Itkor, P., Lee, M, Shin, J., & Lee, Y. S. (2022). Promoting sustainable packaging applications in the circular economy by exploring and advancing molded pulp materials for food products: a review. Critical Reviews in Food Science and Nutrition, 15,1–16.https://doi.org/10.1080/10408398.2022.2088686
Smith, M., Love, D. C., Rochman, C. M., & Neff, R. A. (2018). Microplastics in Seafood and the Implications for Human Health. Current Environmental Health Reports, 5(3), 375–86. https://doi: 10.1007/s40572-018-0206-z
Suiter, A. M., & Sarli, C. C. (2019). Selecting a Journal for Publication: Criteria to Consider. Missouri Medicine,116(6),461–5. PMID: 31911720, PMCID: PMC6913840.
Thompson, R. C. (2004). Lost at Sea: Where Is All the Plastic? Science, 304(5672),838–8. https://doi.org/10.1126/science.1094559
Van Cauwenberghe, L., & Janssen, C. R. (2014). Microplastics in bivalves cultured for human consumption. Environmental Pollution, 193(0269-7491),65–70. https://doi.org/10.1016/j.envpol.2014.06.010
Wagner, M., Scherer, C., Alvarez-Muñoz, D., Brennholt, N., Bourrain, X., Buchinger, S., Fries, E. Grosbois, C., Klasmeier, J., Marti, T., Rodriguez-Mozaz, S., Urbatzka, R. Dick Vethaak, A. Winther-Nielsen, M. & Reifferscheid, G. (2014). Microplastics in freshwater ecosystems: what we know and what we need to know. Environmental Sciences Europe, 26(1). https://doi.org/10.1186/s12302-014-0012-7
Wang, Y., Xu, X., & Jiang, G. (2023). Microplastics exposure promotes the proliferation of skin cancer cells but inhibits the growth of normal skin cells by regulating the inflammatory process. Ecotoxicology and Environmental Safety, 267, 115636. https://doi.org/10.1016/j.ecoenv.2023.115636
Wang, L. (2016). The structure and comparative advantages of China’s scientific research: Quantitative and qualitative perspectives. Scientometrics, 106, 435-452. https://doi.org/10.1007/s11192-015-1650-2
Willert, H. G., Semlitsch, M., & Peltier, L. F. (1996). Tissue reactions to plastic and metallic wear products of joint endoprostheses. Clinical Orthopaedics and Related Research®, 333, 4-14.
Wright, S.L ., & Kelly, F. J. (2017). Plastic and Human Health: a Micro Issue? Environmental Science & Technology, 51(12), 6634–47. https:// doi.org/10.1021/acs.est.7b00423
Yan, Z., Liu, Y., Zhang, T., Zhang, F., Ren, H, & Zhang, Y. (2021). Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status. Environmental Science & Technology, 56(1), 414–21. https://doi: 10.1021/acs.est.1c03924
Yitao, Su., Chao, Y., Huajun, L., Siqi, Z., Zhang, R., Dong, Y., D., Tanveer, S. K., & Hai, J. (2022). Health risk analysis of microplastics in soil in the 21st century: A scientometrics review. Frontiers in Environmental Science, (10), 976237. https:// doi.org/10.3389/fenvs.2022.976237
Zamora, A. M. Caterbow, A., Nobre, C. R., Duran, C. Muffett, C. Flood, C., Rehmer, C. Chmnitz, C. Lauwigi, C. Arkin, C. Da Costa, C. Teles, D. B., Amorim, D. Azoulay, D., Knoblauch, D., Seeger, D. Moun, D., Da Silveira, I., Patton, J. Hausmann, J., Faroni-Perez, L., Guerrero, L. Mederake, L. Xavier, L.Y., Vianna, M., Fernandez, M. Montenegro, M. Eriksen, M. Santos, M. Ziebarth, N. Marcucci, N., Speranskaya, O., Zimermann, P., Da Rocha, R. L., Kallee, U. Ribeiro, V. V., Hernandez, V Gürtler, S., & Feit, S. (2020). Atlas do Plástico: Fatos e números sobre o mundo dos polímeros. https://br.boell.org/pt-br/2020/11/29/atlas-do-plastico .
Zarus, G. M., Muianga, C., Brenner, S., Stallings, K., Casillas, G., Pohl, H. R., Mumtaz, M. M., & Gehle, K. (2023). Worker studies suggest unique liver carcinogenicity potential of polyvinyl chloride microplastics. American journal of industrial medicine, 66(12), 1033-1047. https://doi.org/10.1002/ajim.23540
Zhang, D., Wu, C., Liu, Y., Li, W., Li. S., Peng, L., Kang, L., Ullah, S. Gong, Z., Li, Z. Ding, D., Jin, Z., & Huang, H. (2024). Microplastics are detected in human gallstones and have the ability to form large cholesterol-microplastic heteroaggregates. Journal of hazardous materials, 467,133631–1. https://doi: 10.1016/j.jhazmat.2024.133631
Ziani, K., Ioniță-Mîndrican, C. B., Mititelu, M., Neacșu, S. M., Negrei, C., Moroșan, E., Doina Drăgănescu, D., & Olivia-Teodora, P. (2023). Microplastics: A Real Global Threat for Environment and Food Safety: A State of the Art Review. Nutrients, 15(3):617. https://doi: 10.3390/nu15030617
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2025 Adriana Lamanna Puga; Rossano Pecoraro; Samira da Guia Mello Portugal; Christina Wyss Castelo Branco
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Los autores que publican en esta revista concuerdan con los siguientes términos:
1) Los autores mantienen los derechos de autor y conceden a la revista el derecho de primera publicación, con el trabajo simultáneamente licenciado bajo la Licencia Creative Commons Attribution que permite el compartir el trabajo con reconocimiento de la autoría y publicación inicial en esta revista.
2) Los autores tienen autorización para asumir contratos adicionales por separado, para distribución no exclusiva de la versión del trabajo publicada en esta revista (por ejemplo, publicar en repositorio institucional o como capítulo de libro), con reconocimiento de autoría y publicación inicial en esta revista.
3) Los autores tienen permiso y son estimulados a publicar y distribuir su trabajo en línea (por ejemplo, en repositorios institucionales o en su página personal) a cualquier punto antes o durante el proceso editorial, ya que esto puede generar cambios productivos, así como aumentar el impacto y la cita del trabajo publicado.
