Bacteriological profile and variables related to neoplastic wound in patient under palliative care: cross-sectional study
DOI:
https://doi.org/10.33448/rsd-v9i8.5460Keywords:
Wounds and Injuries; Palliative Care; Oncology Nursing.Abstract
Objective: to verify the association between bacteriological profile and variables related to neoplastic wounds of patients under palliative care. Method: Cross-sectional study, with a sample composed of 36 patients admitted to the wards of the National Cancer Institute José Alencar Gomes da Silva - Unit IV. Data collection took place between the months of October and December 2018, using a specific form. In the data analysis, descriptive measures and Fischer/chi-square test were used at the 5% significance level (α = 0.05). Results: The sample was composed by 36 individuals, 19 (52.78%) of whom were female, with a predominant percentage of metastasis formation (63.89%). There is a strong association between the variables palliative radiotherapy and the presence of Pseudomonas sp. (p = 0.02), type of primary tumor and the presence of Citrobacter sp. and Acinetobacter sp. (p <0.001) and location of the neoplastic wound in the presence of Citrobacter sp. (p = 0.03) and Acinetobacter sp. (p = 0.01). Palliative chemotherapy does not favor an increase in biofilm in the neoplastic wound, and it is not associated with any bacterial genus. The main bacteria identified were Pseudomonas sp., Morganella sp., Klebsiella sp. and Proteus sp.. Conclusion: the treatment with radiotherapy, the type of primary tumor and the location of the tumor wound have a significant association with the bacteriological profile of the lesions and, therefore, the collection of swab and antibiogram analysis of the neoplastic wounds is recommended to improve nursing care .
References
Agra, G., Fernandes, M. A., Platel, I. C. dos S., & Freire, M. E. M. (2013). Cuidados Paliativos ao Paciente Portador de Ferida Neoplásica: uma Revisão Integrativa da Literatura Palliative Care for the Patient with Neoplastic Wound: an Integrative Literature Review. Revista Brasileira de Cancerologia, 59(1), 95–104. http://www1.inca.gov.br/rbc/n_59/v01/pdf/16-cuidados-paliativos-ao-paciente-portador-de-ferida-neoplasica.pdf
Beretta, L., Santos, M., Santos, W., Fuly, P. S. C., & Berardinelli, L. (2020). Resiliência no processo do cuidado aos pacientes com feridas tumorais malignas: revisão integrativa. Research, Society and Development, 9(4), e117942922. https://doi.org/http://dx.doi.org/10.33448/rsd-v9i4.2922)
Brito, D., Agra, G., & Costa, M. (2017). Cuidados Paliativos a Pacientes com Ferida Neoplásica: Uma Perspectiva para a Assistência de Enfermagem Cuidados Paliativos a Pacientes com Ferida Neoplásica: Uma Perspectiva para a Assistência Autores. Journal of Aging and Innovation, 6(3), 28–38.
Castro, D. L. V., & Santos, V. L. C. de G. (2015). Controlling wound odor with metronidazole: A systematic review. Revista da Escola de Enfermagem da USP, 49(5), 858–863. https://doi.org/10.1590/S0080-623420150000500021
Castro, M. C. F., Santos, W. A., Fuly, P. dos S. C., Santos, M. L. S. C., & Garcia, T. R. (2017). Intervenções de enfermagem para pacientes oncológicos com odor fétido em ferida tumoral. Aquichan, 17(3), 243–256. https://doi.org/10.5294/aqui.2017.17.3.2
Draper, C. (2005). The management of malodour and exudate in fungating wounds. British Journal of Nursing, 14(11). https://doi.org/10.12968/bjon.2005.14.sup2.18210
Fromantin, I., Seyer, D., Watson, S., Rollot, F., Elard, J., Escande, M. C., De Rycke, Y., Kriegel, I., & Garde, V. L. (2013). Bacterial floras and biofilms of malignant wounds associated with breast cancers. Journal of Clinical Microbiology, 51(10), 3368–3373. https://doi.org/10.1128/JCM.01277-13
Gericher, U. (2008). Acinetobacter Molecular Biology. Caister Academic Press
Gozzo, T. de O., Tahan, F. P., Andrade, M. de, Nascimento, T. G. do, & Prado, M. A. S. (2014). Occurrence and management of neoplastic wounds in women with advanced breast cancer. Escola Anna Nery - Revista de Enfermagem, 18(2), 270–276. https://doi.org/10.5935/1414-8145.20140039
Instituto Nacional de Câncer José Alencar Gomes da Silva. (2019). Estimativa 2020: incidência de câncer no Brasil.
Instituto Nacional de Câncer. (2011). Tratamento e controle de feridas tumorais e úlceras por pressão no câncer avançado. INCA.
http://bvsms.saude.gov.br/bvs/publicacoes/inca/Feridas_Tumorais.pdf
Lisboa, I. N. D., & Valença, M. P. (2016). Caracterização de pacientes com feridas neoplásicas. Estima, 14(1), 21–28. https://doi.org/10.5327/z1806-3144201600010004
Lund-Nielsen, B., Adamsen, L., Gottrup, F., Rorth, M., Tolver, A., & Jorn Kolmos, H. (2011). Qualitative bacteriology in malignant wounds - A prospective, randomized, clinical study to compare the effect of honey and silver dressingsi. Ostomy Wound Management, 57(7), 28–36.
Matsubara, M. (2015). Feridas e estomas em oncologia: uma abordagem interdisciplinar. Lemar.
Silva, V., Marcoleta, A., Silva, V., Flores, D., Aparicio, T., Aburto, I., Latrach, C., & Febré, N. (2018). Prevalencia y perfil de susceptibilidad antimicrobiana en bacterias aisladas de úlceras crónicas infectadas en adultos. Revista Chilena de Infectología, 35(2), 155–162. https://doi.org/10.4067/s0716-10182018000200155
Watanabe, K., Shimo, A., Tsugawa, K., Tokuda, Y., Yamauchi, H., Miyai, E., Takemura, K., Ikoma, A., & Nakamura, S. (2016). Safe and effective deodorization of malodorous fungating tumors using topical metronidazole 0.75 % gel (GK567): a multicenter, open-label, phase III study (RDT.07.SRE.27013). Supportive Care in Cancer, 24(6), 2583–2590. https://doi.org/10.1007/s00520-015-3067-0
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