The green tea catechins’s benefits in the type 2 Diabetes Mellitus: an integrative revision

Authors

DOI:

https://doi.org/10.33448/rsd-v9i8.5870

Keywords:

Catechin; Green tea; Diabetes Mellitus type 2; Oxidative stress.

Abstract

Diabetes Mellitus (DM) is a disease characterized by causing dysfunction in glucose metabolism. Conduct a review that lists the beneficial effects of catechins present in green tea related to type 2 Diabetes Mellitus. The search for articles occurred by the association of keywords: green tea, catechins, type 2 diabetes mellitus and oxidative stress. The terms were searched in English and Portuguese from 2013 to 2018 on the basis of periodocos, Lilacs; Medline, pubmed, Web of Science and Scielo. Of the 20 articles found with the association of these keywords, 7 were selected. The beneficial effects of catechins in relation to Diabetes Mellitus 2 and their possible effective actions on the pathology in question were analyzed. It was observed that the catechins present in green tea have antioxidant properties, which can protect or reduce oxidative damage in diabetic patients, helping to control DM2 and other pathologies; Epigallocatechin-3-gallate (EGCG) was the catechin found in greater quantity and the one with the greatest benefit in relation to DM2. This review contributes to the discussions about the aid of green tea for the control of Diabetes Mellitus 2, it was observed that the catechins present in green tea have beneficial effects in relation to DM2 and that EGCG had greater biological activity, as well as having the highest concentration in the leaf of the Camellia Sinensis plant. It is worth mentioning the importance of conducting more clinical studies that evaluate the beneficial effects, and the pharmacological and biological activity of catechins in green tea in isolation.

Author Biography

Eudânia Vieira da Silva Cavalcante, Universidade Federal do Piauí

Departamento de Nutrição

References

Basu, A., Betts, N. M., Mulugeta, A., Tong, C., Newman, E., & Lyons, T. J. (2013). Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome. Nutrition Research, 33(3), 180–187. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603270/. doi: 10.1016/j.nutres.2012.12.010

Brasil. Ministério da Saúde. Departamento de Atenção Básica. (2013). Estratégias para o cuidado da pessoa com doença crônica: Diabetes Mellitus. Brasília - DF. [acesso em 22 set 2019]. Retrieved from: https://bvsms.saude.gov.br/bvs/publicacoes/estrategias_cuidado_pessoa_diabetes_mellitus_cab36.pdf

Carloni, P., Tiano, L., Padella, L., Bacchetti, T., Customu, C., Kay, A., & Damiani, E. (2013). Antioxidant activity of white, green and black tea obtained from the same tea cultivar. Rev Food Research International, 53(2), 900-908. Retrieved from: https://www.sciencedirect.com/science/article/abs/pii/S0963996912003018. doi: 10.1016/j.foodres.2012.07.057

Castro, I. B., Câmara G. B., Pontes, J. F., Viana, D. L., Souza, R. P., Trajano, E. D. S. N., Lira, R. B. B., & Barbosa, L. S. L. T. (2020). Estratégias nutricionais no tratamento do diabetes mellitus: revisão bibliográfica. Rev Research, Society and Development, 9(2), e133922193. Retrieved from: https://rsd.unifei.edu.br/index.php/rsd/article/view/2193/1773. doi: 10.33448/rsd-v9i2.2193

Deusing, D. J., Winter, S., Kler, A., Kriesl, E., Bonnländer, B., Wenzel, U., & Fitzenberger, E. (2015). A catechin-enriched green tea extract prevents glucose-induced survival reduction in Caenorhabditis elegans through sir-2.1 and uba-1 dependent hormesis. Rev Fitoterapia, 102, 163-170. Retrieved from: https://www.sciencedirect.com/science/article/abs/pii/S0367326X15000593?via%3Dihub. doi: 10.1016/j.fitote.2015.03.005.

Freitas, H. C. P., & Navarro, F. (2007). O chá verde induz o emagrecimento e auxilia no tratamento da obesidade e suas comorbidades. Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 1(2), 16-23. Retrieved from: http://www.rbone.com.br/index.php/rbone/article/view/14/12.

Hartley, L., Flowers, N., Holmes, J., Clarke, A., Stranges, S., Hooper, L., & Rees, K. (2013). Green and black tea for the primary prevention of cardiovascular disease. In K. Rees (Ed.), Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd.

Ihm, S. H., Lee, J. O., Kim, S. J., Seung, K. B., Schini-Kerth, V. B., Chang, K., & Oak, M. H. (2015). Catechin prevents endothelial dysfunction in the prediabetic stage of OLETF rats by reducing vascular NADPH oxidase activity and expression. Rev Atherosclerosis, 206(1), 47-53. Retrieved From: https://pubmed.ncbi.nlm.nih.gov/19264308/. doi: 10.1016/j.atherosclerosis.2009.01.036

Komes, D., Horžić, D., Belščak, A., Ganić, K. K., & Vulić, I. (2010). Green tea preparation and its influence on the content of bioactive compounds. Rev. Food Research International., 43(1), 167-176. Retrieved From: https://www.sciencedirect.com/science/article/abs/pii/S0963996909002877. doi: 10.1016/j.foodres.2009.09.022

Liu, J., Tang, Y., Feng, Z., Liu, J., Liu, J., & Long, J. (2014). (–)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto–Kakizaki rats. Free radical research, 48(8): 898-906. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/24797301/. doi: 10.3109 / 10715762.2014.920955

Lodi, V. M., & Navarro, F. (2011). Efeitos do chá verde (Camellia sinensis) na redução da gordura corporal e circunferência abdominal de mulheres praticantes de JUMP FIT de uma academia do município de São José-SC. Revista Brasileira de Nutrição Esportiva, 5(26), 122-29. Retrieved from: http://www.rbne.com.br/index.php/rbne/article/view/243/237.

Moreschi, C., Rempel, C., Siqueira, D. F., Pissaia, L. F., Almeida, G., & Bedin, B. B. (2020). Consequências do diabetes na qualidade de vida dos usuários na perspectiva do professional de saúde. Rev Research, Society and Development, 9(7), 1-19. Retrieved from: https://rsd.unifei.edu.br/index.php/rsd/article/viewFile/4818/4222. doi: 10.33448/rsd-v9i7.4818

Özyurt, H., Luna, C., & Estévez, M. (2016). Redox chemistry of the molecular interactions between tea catechins and human serum proteins under simulated hyperglycemic conditions. Rev Food & function, 7(3), 1390-1400. Retrieved from: https://pubs.rsc.org/en/content/articlepdf/2016/fo/c5fo01525a. doi: 10.1039/C5FO01525A

Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: an overview. Journal of Nutritional Science, 5(e47), 12-29. Retrieved from: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/C0E91D3851345CEF4746B10406908F52/S2048679016000410a.pdf/flavonoids_an_overview.pdf. doi: 10.1017/jns.2016.41

Rains, T. M., Agarwal, S., & Maki, K. C. (2011). Antiobesity effects of green tea catechins: a mechanistic review. The Journal of Nutritional Biochemistry, 22(1), 1–7. Retrieved from: https://www.essentialnutrition.com.br/media/artigos/preaction/13.pdf. doi: 10.1016/j.jnutbio.2010.06.006

Rizvi, S. I., Zaid, M. A., Anis, R., & Mishra, N. (2013). Protective role of tea catechins against oxidation‐induced damage of type 2 diabetic erythrocytes. Rev Clinicaland experimental pharmacologyandphysiology, 32(1-2), 70-75. Retrieved from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1681.2005.04160.x. doi: 10.1111/j.1440-1681.2005.04160.x

Schmitz, W., Saito, A. Y., Estevão, D., & Saridakis, H. O. (2005). O chá verde e suas ações como quimioprotetor. Semina: Rev Semina: Ciências Biológicas e da Saúde, 26(2), 119-130. Retrieved from: http://www.uel.br/revistas/uel/index.php/seminabio/article/view/3561. doi: 10.5433/1679-0367.2005v26n2p119

Senger, A. E. V., Schwanke, C. H. A., & Gottlieb, M. G. V. (2016). Chá verde (Camelliasinensis) e suas propriedades funcionais nas doenças crônicas não transmissíveis. Rev Scientia Medica, 20(4), 292-300. Retrieved from: https://pdfs.semanticscholar.org/1a43/d990936faefcc20e6781cf6b3a60a7763786.pdf?_ga=2.34953506.2056171591.1592636557-977858230.1592636557.

Sociedade Brasileira de Diabetes (SBD). (2017). O que é Diabetes? São Paulo. [acesso em 22 set 2019]. Retrieved from: https://www.diabetes.org.br/publico/diabetes/oque-e-diabetes

Sousa, I. M. C., Bodstein, R. C. A., Tesser, C. D., Santos, F. A. S., & Hortale, V. A. (2012). Práticas integrativas e complementares: oferta e produção de atendimentos no SUS e em municípios selecionados. Cad. Saúde Pública, 28(11), 2143- 2154. Retrieved from: https://www.scielo.br/pdf/csp/v28n11/14.pdf. doi: 10.1590/S0102-311X2012001100014

Spadiene, A., Savickiene, N., Ivanauskas, L., Jakstas, V., Skesters, A., Silova, A., & Rodovicius, H. (2014). Antioxidant effects of Camellia sinensis L. extract in patients with type 2 diabetes. Journal of food and drug analysis, 22(4), 505-511. Retrieved from: https://reader.elsevier.com/reader/sd/pii/S1021949814000465?token=2E4299C9F446170B559A19C6D928D646FD1AE27F4B322D164B90452BA77959CDA93AA1CFD853B6EC5CC0DA6C9CCF3DB0. doi: 10.1016/j.jfda.2014.04.001

Uchiyama, Y., Suzuki, T., Mochizuki, K., & Goda, T. (2013). Dietary supplementation with a low dose of (−)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats. Journal of nutritional science and vitaminology, 59(6), 541-547. Retrieved from: https://www.jstage.jst.go.jp/article/jnsv/59/6/59_541/_pdf/-char/en. doi: 10.3177/jnsv.59.541

Vasconcelos, D. A., Alcoforado, G. G., & Lima, M. M. O. (2010). Plantas medicinais de uso caseiro: conhecimento popular na região do centro do município de Floriano/PI. V. Congresso Norte e Nordeste de Pesquisa e Inovação, Maceió, 2010. Anais CONNEPI. [acesso em 22 set 2019]. Retrieved from: http://connepi.ifal.edu.br/ocs/index.php/connepi/CONNEPI2010/paper/viewFile/455/293

Walkowiak, J., Bajerska, J., Kargulewicz, A., Lisowska, A., Siedlerski, G., Szczapa, T., & Grzymisławski, M. (2013). Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans. Rev Acta Biochimica Polonica, 60(3), 481–486. Retrieved from: http://www.actabp.pl/pdf/3_2013/481.pdf. doi: 10.18388/abp.2013_2010

Yamamoto, T., Juneja, L. R., Chu, S., & Kim, M. (1997). Chemistry and Applications of Green Tea. New York: Boca Raton, 176.

Yang, X., Li, Y., Li, Y., Ren, X., Zhang, X., Hu, D., & Shang, H. (2017). Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies. Rev Frontiers in Physiology, 8, 1–16. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572357/. doi: 10.3389/fphys.2017.00600

Zink, A., & Traidl-Hoffmann, C. (2015). Green tea in dermatology - myths and facts. Journal Der Deutschen Dermatologischen Gesellschaft, 13(8), 768–775. Retrieved from: https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.12737. doi: 10.1111/ddg.12737

Published

15/07/2020

How to Cite

CAVALCANTE, E. V. da S.; SILVA, T. de M.; FIGUEIREDO, M. C. F. de; NASCIMENTO, J. M. F. do; MEDEIROS, S. R. A.; OLIVEIRA, A. S. S. de; ALMEIDA, A. A. C. de; CARVALHO, R. B. F. de; PEREIRA-FREIRE, J. A. The green tea catechins’s benefits in the type 2 Diabetes Mellitus: an integrative revision. Research, Society and Development, [S. l.], v. 9, n. 8, p. e532985870, 2020. DOI: 10.33448/rsd-v9i8.5870. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/5870. Acesso em: 26 dec. 2024.

Issue

Section

Health Sciences