Trends in hospitalization of patients with Acute Heart Failure

Authors

DOI:

https://doi.org/10.33448/rsd-v9i9.7790

Keywords:

Heart Failure; Epidemiology; Hospitalization; Therapeutics.

Abstract

Objective: Identify the causes of decompensation and trends in the classification and treatment of hospitalized patients with heart failure. Methods: Observational study, carried out in a private cardiology reference hospital in the city of Aracaju / SE. Medical records from June 2015 to August 2018 were analyzed and questionnaires were applied to patients over 18 years old, who presented with acute form or acute exacerbation of chronic Heart Failure. Results: 180 patients were included, with a mean of 73 years and a male prevalence (52.2%). It was identified that 94.4% of the patients had dyspnea, 86.1% had a history of systemic arterial hypertension, arrhythmia (33.3%) was the main cause of decompensation and the hypertensive etiology was recognized in 39.4% of the cases. Heart Failure with reduced ejection fraction was identified in 50.7%, with a greater tendency in males (p<0.0001) and in younger people (p=0.001). Diuretics (82.3%) and beta-blockers (58.3%) were the main medications used chronically and during hospitalization 83.9% used loop diuretics for symptomatic improvement. The average hospital stay was 12.45 days and of the 6.1% who died, 72.7% required intensive care. Conclusion: The characteristics identified in patients with Heart Failure such as the association of several comorbidities and the growing diagnosis of patients with preserved ejection fraction demonstrate the need for new strategies to face this syndrome.

References

Adams Jr, K. F., Fonarow, G. C., Emerman, C. L., LeJemtel, T. H., Costanzo, M. R., Abraham, W. T., ... & ADHERE Scientific Advisory Committee and Investigators. (2005). Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). American heart journal, 149(2), 209-216.

Albuquerque, D. C. D., Souza Neto, J. D. D., Bacal, F., Rohde, L. E. P., Bernardez-Pereira, S., Berwanger, O., & Almeida, D. R. (2015). I Brazilian registry of heart failure-clinical aspects, care quality and hospitalization outcomes. Arquivos brasileiros de cardiologia, (AHEAD), 0-0.

Bettencourt, P., Azevedo, A., Pimenta, J., Friões, F., Ferreira, S., & Ferreira, A. (2004). N-terminal–pro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients. Circulation, 110(15), 2168-2174.

Bocchi, E. A., Guimarães, G., Tarasoutshi, F., Spina, G., Mangini, S., & Bacal, F. (2009). Cardiomyopathy, adult valve disease and heart failure in South America. Heart, 95(3), 181-189.

Bocchi, E. A., Marcondes-Braga, F. G., Bacal, F., Ferraz, A. S., Albuquerque, D., & Rodrigues, D. (2012). Atualização da diretriz brasileira de insuficiência cardíaca crônica-2012. Arquivos brasileiros de Cardiologia, 98(1), 1-33.

Castro, R. A. D., Aliti, G. B., Linhares, J. C., & Rabelo, E. R. (2010). Adesão ao tratamento de pacientes com insuficiência cardíaca em um hospital universitário. Revista Gaúcha de Enfermagem, 31(2), 225-231.

Ceia, F., Fonseca, C., Mota, T., Morais, H., Matias, F., de Sousa, A., ... & EPICA Investigators, O. B. O. T. (2002). Prevalence of chronic heart failure in Southwestern Europe: the EPICA study. European journal of heart failure, 4(4), 531-539.

Ciapponi, A., Alcaraz, A., Calderón, M., Matta, M. G., Chaparro, M., Soto, N., & Bardach, A. (2016). Burden of heart failure in Latin America: a systematic review and meta-analysis. Revista Española de Cardiología (English Edition), 69(11), 1051-1060.

Cleland, J. G. F., Swedberg, K., Follath, F., Komajda, M., Cohen-Solal, A., Aguilar, J. C., ... & Madeira, H. C. (2003). The EuroHeart Failure survey programme—a survey on the quality of care among patients with heart failure in Europe: Part 1: patient characteristics and diagnosis. European heart journal, 24(5), 442-463.

Departamento de Informática do Sistema Único de Saúde – DATASUS. Internações Hospitalares segundo Capítulo do CID-10 entre Junho de 2015 a Agosto de 2018. Recuperado de: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sih/cnv/niuf.def.

Farmakis, D., Parissis, J., Lekakis, J., & Filippatos, G. (2015). Acute heart failure: epidemiology, risk factors, and prevention. Revista Española de Cardiología (English Edition), 68(3), 245-248.

Felker, G. M., Adams, K. F., Gattis, W. A., & O'Connor, C. M. (2004). Anemia as a risk factor and therapeutic target in heart failure. Journal of the American College of Cardiology, 44(5), 959-966.

Francis, G. (2006). Acute decompensated heart failure: the cardiorenal syndrome. Cleveland Clinic journal of medicine, 73(2), S8.

Gerber, Y., Weston, S. A., Redfield, M. M., Chamberlain, A. M., Manemann, S. M., Jiang, R., ... & Roger, V. L. (2015). A contemporary appraisal of the heart failure epidemic in Olmsted County, Minnesota, 2000 to 2010. JAMA internal medicine, 175(6), 996-1004.

Gheorghiade, M., & Filippatos, G. (2005). Reassessing treatment of acute heart failure syndromes: the ADHERE Registry. European Heart Journal Supplements, 7(suppl_B), B13-B19.

Kirsztajn GM, Souza E, Romão Jr JE, Bastos MG, Meyer F, Andrada NC. Doença Renal Crônica (Pré-terapia Renal Substitutiva): Diagnóstico. In: Associação Médica Brasileira e Conselho Federal de Medicina. Projeto diretrizes. São Paulo: Associação Médica Brasileira e Conselho Federal de Medicina, 2011:1-22.

Kociol, R. D., Hammill, B. G., Fonarow, G. C., Klaskala, W., Mills, R. M., Hernandez, A. F., & Curtis, L. H. (2010). Generalizability and longitudinal outcomes of a national heart failure clinical registry: Comparison of Acute Decompensated Heart Failure National Registry (ADHERE) and non-ADHERE Medicare beneficiaries. American heart journal, 160(5), 885-892.

Lam, C. S., Donal, E., Kraigher‐Krainer, E., & Vasan, R. S. (2011). Epidemiology and clinical course of heart failure with preserved ejection fraction. European journal of heart failure, 13(1), 18-28.

Martins, H., Pedro, N., Castellano, M., Monteiro, P., Moura, J. J., & Providência, L. A. (2011). Síndrome cardio-renal: os desafios no tratamento da insuficiência cardíaca.

Nieminen, M. S., Brutsaert, D., Dickstein, K., Drexler, H., Follath, F., Harjola, V. P., ... & Ponikowski, P. (2006). EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population. European heart journal, 27(22), 2725-2736.

Pinho-Gomes, A. C., Cardoso, J. S., Azevedo, L. F., Almeida, R., Pinho, T., & Maciel, M. J. (2013). Characterization of acute heart failure hospitalizations in a Portuguese cardiology department. Revista Portuguesa de Cardiologia, 32(7-8), 567-575.

Ponikowski, P., Anker, S. D., AlHabib, K. F., Cowie, M. R., Force, T. L., Hu, S., ... & Samal, U. C. (2014). Heart failure: preventing disease and death worldwide. ESC heart failure, 1(1), 4-25.

Précoma, D. B., Oliveira, G. M. M. D., Simao, A. F., Dutra, O. P., Coelho, O. R., Izar, M. C. D. O., ... & Scherr, C. (2019). Updated Cardiovascular Prevention Guideline of the Brazilian Society of Cardiology-2019. Arquivos brasileiros de cardiologia, 113(4), 787-891.

Rabelo-Silva, E. R., Saffi, M. A. L., Aliti, G. B., Feijó, M. K., Linch, G. F. D. C., Sauer, J. M., & Martins, S. M. (2018). Fatores precipitantes de descompensação da insuficiência cardíaca relacionados a adesão ao tratamento: estudo multicêntrico-EMBRACE. Revista Gaúcha de Enfermagem, 39.

Rohde, L. E. P., Montera, M. W., Bocchi, E. A., Clausell, N. O., Albuquerque, D. C. D., Rassi, S., ... & Barretto, A. C. P. (2018). Diretriz brasileira de insuficiência cardíaca crônica e aguda. Arquivos Brasileiros de Cardiologia, 111(3), 436-539.

Savarese, G. (2017). Division of Cardiology, Department of Medicine, Karolinska Insitutet, Stockholm, Sweden, Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden, Lund LH, Division of Cardiology, Department of Medicine, Karolinska Insitutet, Stockholm, Sweden, Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden. Global Public Health Burden of Heart Failure. Global Public Health Burden of Heart Failure. Card Fail Rev, 3, 7.

Steinberg, B. A., Zhao, X., Heidenreich, P. A., Peterson, E. D., Bhatt, D. L., Cannon, C. P., ... & Fonarow, G. C. (2012). Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes. Circulation, 126(1), 65-75.

Published

05/09/2020

How to Cite

Dantas, L. R. C. F. ., Jesus, C. V. F. de ., Dantas, J. G. L. ., Martins , B. M. ., Almeida , A. O. ., Sousa, A. C. S. ., & Lima, S. O. (2020). Trends in hospitalization of patients with Acute Heart Failure. Research, Society and Development, 9(9), e725997790. https://doi.org/10.33448/rsd-v9i9.7790

Issue

Section

Health Sciences