A reflection on in vitro methodologies for estimating the glycemic index of foods

Authors

DOI:

https://doi.org/10.33448/rsd-v9i10.8572

Keywords:

Glucose; Starch; Blood glucose; Carbohydrates.

Abstract

The Glycemic Index (GI) expresses the relative impact of the food's carbohydrate on the plasma glucose concentration, reflecting the fact that foods with a greater increase in the glycemic response after ingestion have a higher GI and vice versa. Knowledge of the GI of foods can guide the choice of the most appropriate foods for the composition of a healthy diet. However, studies to determine the glycemic index of foods are laborious and time consuming, since they are carried out with the participation of human volunteers. The interest in in vitro methods that can estimate this index has been growing. In this sense, the present study aimed to discuss the application of these in vitro methodologies in the estimation of the “glycemic index”, through a brief narrative review and the test of tests chosen to illustrate the reflection on the theme. The two methods tested here were able to respond to the starch sample and observing the quotes about the methodology allows raising questions such as: the use of in vitro methodologies presents itself as something promising, easy and quick to execute, but there is a need the adoption of a single in vitro methodology of choice, to be equated with in vivo, which allows comparison between generated data and the formation of a database of in vitro GI values.

References

Alongi, M., Melchior, S., & Anese, M. (2019). Reducing the glycemic index of short dough biscuits by using apple pomace as a functional ingredient. LWT - Food Science and Technology, 100, 300–305.

Arnhold, T. B., Garlipp, D. C., Fiel, G., Grohe, M., Guth, F., Rasche, J., Hoerlle, J. L. & Lopes, A. L. (2016) Correlação dos valores de lipídios sanguíneos e parâmetros antropométricos em sujeitos praticantes de treinamento de força e em sedentários. Revista Brasileira de Prescrição e Fisiologia do Exercício, 10 (62), 717-727.

Barclay, A. W., Petocz, P., McMillan-Price, J., Flood, V. M., Prvan, T., & Mitchell, P. (2008). Glycemic index, glycemic load, and chronic disease risk, a meta-analysis of observational studies. American Journal of Clinical Nutrition, 87, 627-637.

Beebe, C. (1999). Diets with a low glycemic index: not ready for practice yet! Nutrition Today, 34(2), 82-86.

Bioclin® Glicose Monoreagente K082. Recuperado de https://www.bioclin.com.br/sitebio clin/wordpress/wpcontent/uploads/arquivos/instrucoes/INSTRUCOES_GLICOSE_MONOREAGENTE.pdf

Bohn, T., Carriere, F., Day, L., et al. (2018) Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models? Critical Reviews in Food Science and Nutrition, 58 (13), 2239-2261.

Borges, M. T. M. R., Parazzi, C., & Piedade, S. M. D. S. (1987). Avaliação de Métodos Químicos de Determinação de Açúcares Redutores em Xaropes. Anais do 4o. Congresso Nacional da STAB. VIII Convenção da ACTALAC, Olinda, Pe, Brasil, 8-13.

Bornet, F. R. J., Fontvieille, A. M., Rizkalla, S., Colonna, P., Blayo, A., Mercier, C., & Slama G. (1989). Insulin and glycemic responses in healthy humans to native starches processed in different ways: correlation with in vitro a-amylase hydrolysis. American Journal of Clinical Nutrition, 50, 315-523.

Brand, J. C., Nicholson, P. L., Thorburn, A. W., & Truswell, A. S. (1985). Food processing and the glycemic index. American Journal of Clinical Nutrition, 42, 1192-1196.

Brand, J. C., Snow, B. J., Nabhan G. P., & Truswel, A. S. (1990). Plasma glucose and insulin responses to traditional Pima Indian meals. American Journal of Clinical Nutrition, 5, 416-420.

Brand-Miller, J., & Foster-Powell, K. (1999). Diets with a low glycemic index: from theory to practice. Nutrition Today, 34(2), 64-72.

Brouns, F., Bjorck, I., Frayn, K. N., Gibbs, A. L., Lang, V., Slama, G., et al (2005). Glycaemic index methodology. Nutrition Research Review, 18, 145-171.

Capriles, V. D., Guerra-Matias, A. C., & Areas J. A. G (2009). Marcador in vitro da resposta glicêmica dos alimentos como ferramenta de auxílio à prescrição e avaliação de dietas. Revista de Nutrição, 22, 549-557.

Chung, H. J. Shin, D. H., & Lim, S. (2008). In vitro starch digestibility and estimated glycemic index of chemically modified corn starches. Food Research International, 41, 579–585.

Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F (1956). Colorimetric Method form Determination of Sugars and Related Substaces. Nature, 28(3), 350 -356.

Eliasson, A. C (2004). Starch in food – Structure, function and applications. New York: Boca Raton, CRC. 605p.

Franz, M. J. (1999) . In defense of the American Diabetes Association's recomendations on the glycemic index. Nutr Today, 34(2), 78-81.

Frei, M., Siddhuraju, P., & Becker, K. (2003). Studies on the in vitro starch digestibility and the glycemic index of six different indigenous rice cultivars from the Philippines. Food Chemistry, 83, 395-402.

Froslie, K. F., Roislien, J., Qvigstad, E., Godang, K., Bollerslev, J, Voldner, N., Henriksen, T., & Veierod, M. B. (2013). Shape information from glucose curves: Functional data analysis compared with traditional summary measures. BMC Medical Research Methodology, 13, 6.

Gonçalves, C., Rodriguez-Jasso, R. M., Gomes, N., Teixeira, J. A., & Belo, I. (2010). Adaptation of dinitrosalicylic acid method to microtiter plates. Analytical Methods, 2, 2046-2048.

Goñi, I., Garcia-Alonso, A., & Saura-Calixto, F. (1997). A starch hydrolysis procedure to estimate glycemic index. Nutrition Research, 17, 427-437.

Heaton, K. W., Marcus, S. N., Emmett, P. M., & Bolton, C. H. (1988). Particle size of wheat, maize, and oat test meals: effects on plasma glucose and insulin responses and on the rate of starch digestion in vitro. American Journal of Clinical Nutrition, 47, 675-682.

Hon, H. W. H., Wong, T. H. T., Tse, I. M. Y., & Louie, J. C. Y. (2020). The effect of a low glycaemic index diet on reducing day‐long glycaemia in healthy young adults: A randomized crossover trial. Diabetes Obesity and Metabolism, 1– 10.

Jenkins, D. J. A., Ghafari, H., Wolever, T. M. S., Taylor, R. H., Jenkins, A. L., Barker, H. M., Fielden, H., & Bowling, A. C. (1982). Relationship Between Rate of Digestion of Foods and Post-Prandial Glycaemia. Diabetologia, 22, 450-455.

Jenkins, D. J. A., Jenkins, A. L., Wolever, T. M. S., Thompson, L. H., & Rao, A. V. (1986). Simple and Complex Carbohydrates. Nutrition Reviews, 44, 2.

Jenkins, D. J. A., Thomas, M. S., Wolever, R. H., Taylor, H. B., Hashmein, Bowling, A. C., Newman, H. C., Jenkins, A. L. & Goff, D. V. (1981). Glycemic index of foods: a physiological basis for carbohydrates exchange. American Journal of Clinical Nutrition, 34(3), 362-366.

Jenkins, D. J. A., Thorne, M. J., Wolever, T. M. S., Jenkins, A. L., Venkentschwer, R. A., & Thompson, L. U (1987). The effect of starch-protein interaction in wheat on the glycemic response and the rate of in vitro digestion. American Journal of Clinical Nutrition, 45, 946-951.

Jones, J. M. (2007). Glycemic responses definitions. Cereal Food World, 55, 54-55.

Lane, J. H., & Eynon, L. (1934). Determination of reducing sugars by Fehling's solution with methylene blue indicator, Normam Rodge, London, 8p.

Laville, M. (2004). Could glycaemic index be the basis of simple nutritional recommendations? British Journal of Nutrition, 91(6), 803-804.

Lehniger, L., A., Nelson, L. D, Cox, M.M. (1995). Princípios de Bioquímica, (2a ed.), 227 — 228.

Lévêque, E., et al. (2000). Thermophilic archael amylolitic enzymes. Enzyme and Microbial Technology, 26 (1), 3-14.

Lowry, J. R., Thiessen, R. (1950). Studies of the nutritive impairment of proteins heated with carbohydrates: in vitro digestion studies. Archives of Biochemistry, 25(1), 148-156.

Miller, G. L (1959). Use of dinitrosalicylic acid reagent for determination of reducing sugar. Analytical Chemistry, Washington, 31(3) 426-428.

Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C., et al. (2014). A standardised static in vitro digestion method suitable for food-an international consensus. Food & Function, 5, 1113–1124.

Negrulescu, A., Patrulea, V., Mincea, M. M., Ionascu, C., Vlad-Oros, B. A., & Ostafe, V. (2012). Adapting the reducing sugars method with dinitrosalicylic acid to microtiter plates and microwave heating. Journal of the Brazilian Chemical Society, 23(12), 2176-2182.

Nelson, D. L., Cox, M. M (2014). Princípios de bioquímica de Lehninger. Porto Alegre: Artmed, 1328 p.

Obel, L. B (2001). Putting enzymes to work in bakery applications. Cereal Foods World, 46(9), 396-399.

Pi-Sunyer, F. X. (2002). Glycemic index and disease. American Journal of Clinical Nutrition, 76(Suppl):290S-8S.

Ross, S. W., Brand, J. C., Thorburn, A. W., & Truswell, A. S. (1987). Glycemic index of processed wheat products. American Journal of Clinical Nutrition, 46, 631-635.

Sartorelli, D. S., & Cardoso, M. A. (2006). Associação entre carboidratos da dieta habitual e diabetes mellitus tipo 2: evidências epidemiológicas. Arquivos Brasileiros de Endocrinologia e Metabolismo, 50(3), 415-425.

Sheard, N. F., Clark, N. G., Brand-Miller, J. C., Franz, M. J., Pi-Sunyer, F. X., Mayer-Davis E,, et al (2004). Dietary carboidrate (amount and type) in the prevention and management of diabetes. A statement by the American Diabetes Association. Diabetes Care, 27(9), 2266-2270.

Sieri, S., Agnoli, C., Pala, V., Grioni S., Brighenti, F., Pellegrini, N., et al (2017). Dietary glycemic index, glycemic load, and cancer risk: results from the EPIC-Italy study. Scientific Report, 7(1), 94-98.

Silva, F. M., Steemburgo, T., Azevedo, M. J., & Mello, V. D (2009). Papel do índice glicêmico e da carga glicêmica na prevenção e no controle metabólico de pacientes com diabetes mellito tipo 2. Arquivo Brasileiro de Endocrinologia e Metabolismo, 53, 560- 571.

Simsek S., & Nehir El, S. (2015). In vitro starch digestibility, estimated glycemic index and antioxidant potential of taro (Colocasia esculenta L. Schott) corm. Food Chemistry, v.168, 257–261.

Spieth, L. E., Harnish, J. D., Lenders, C. M., Raezer, L. B., Pereira, M., Hangen, S. J., & Ludwig, D. S (2000). A low-glycemic index diet in the treatment of pediatric obesity. Archives of Pediatrics e Adolescent Medicine, 154, 947-51.

Statistica 8.0 (2007). Statistics computer program for Windows, v.1. Tulsa: StatSoft Inc. Software.

Teixeira, R. S. S., Silva, A. S., Ferreira-Leitão, V. S., & Bon, E. P. S (2012). Amino acids interference on the quantification of reducing sugars by the 3,5-dinitrosalicylic acid assay mislead carbohydrase activity measurements. Carbohydrate Research, 363, 33-37.

Williams, S. M., Venn, B. J., Perry, T., Brown, R., Wallace, A., Mann, J. I., et al (2008). Another approach to estimate the reliability of glycaemic index. British Journal of Nutrition, 1, 7-9.

Wolever, T. M. S., Jenkins, D. J. A., Jenkins, A. L., & Josse, R. G. (1991). The glycemic index: methodological and clinical implications. American Journal of Clinical Nutrition, 54, 846-854.

Wong, S., Traianedes, K., O’dea, K. (1985). Factors affecting the rate of starch hydrolysis in legumes. American Journal of Clinical Nutrition, 42, 38-43.

Woolnough, J. W., Monro, J. A., Brennan, C. S., & Bird, A. R. (2008). Simulating human carbohydrate digestion in vitro: a review of methods and the need for standardisation. International Journal of Food Science & Technology, 43, 2245-2256.

World Health Organization. (1998). Carbohydrates in human nutrition. Report of a Toin FAO/WHO expert consulation, 66. Rome: WHO.

Yoon, J. H., Thompson L. U., & Jenkins, D. J. A. (1983). The effect of phytic acid on in vitro rate of starch digestibility and blood glucose response. American Journal of Clinical Nutrition, 835-842.

Zhang, J., Jiang, Y., Liu, Y., Chang, Q., Zhao, Y. & Wu, Q. (2020). The association between glycemic index, glycemic load, and metabolic syndrome: a systematic review and dose–response meta-analysis of observational studies. European Journal of Nutrition, 59, 451–463.

Published

22/09/2020

How to Cite

MOURA, S. R. B. de M. .; CARMO, A. C. M. do; TAVANO, O. L. A reflection on in vitro methodologies for estimating the glycemic index of foods. Research, Society and Development, [S. l.], v. 9, n. 10, p. e1809108572, 2020. DOI: 10.33448/rsd-v9i10.8572. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/8572. Acesso em: 17 nov. 2024.

Issue

Section

Health Sciences