Evaluation of the effectiveness of elastography in differentiating breast nodules
DOI:
https://doi.org/10.33448/rsd-v9i10.9374Keywords:
Breast Nodes; Elastography; B-mode ultrasound.Abstract
Introduction: Breast cancer is among the most common tumors in women. Conventional imaging methods for evaluating breast nodules (USG and mammography) show high rates of sensitivity, but they also have a large number of false positives. In this sense, several authors have described that elastography can assist in this process. It is a relatively recent tool that is available on some USG devices and evaluates the deformity of the tissue in response to an imposed compression, providing information about the elasticity / stiffness of the tissue. With this in mind, the objective of the present study is to evaluate the effectiveness of elastography to differentiate the hitological types of nodules and to compare their effectiveness with the BI-RADS classification. Method: This is a prospective cohort that performed standard ultrasound and strain elastography in patients with breast nodules. Biopsy was performed when necessary. The values of the percentage of rigid area (RA), identified by elastography, were compared between the different classes of the traditional BI-RADS classification, as well as were compared between the benign and malignant groups, characterized from the histopathological findings. Results: In all, 128 female patients were included in the study. It was demonstrated that the BI-RADS groups 4B, 4C and 5 present higher values of percentage of RA. There was a statistically significant difference between the% RA in benign and malignant tumors. Conclusions: The findings of elastography associated with the calculation of a rigid area can increase the diagnostic probability of breast cancer, and can be used in routine breast assessment.
References
Buchberger, W., Niehoff, A., Obrist, P., DeKoekkoek-Doll, P., & Dünser, M. (2000). Clinically and mammographically occult breast lesions: Detection and classification with high-resolution sonography. Seminars in Ultrasound CT and MRI, 21(4), 325–336. https://doi.org/10.1016/S0887-2171(00)90027-1
Coughlin, S. . (2019). Epidemiology of Breast Cancer in Women. In: Ahmad A. (eds) Breast Cancer Metastasis and Drug Resistance. Advances in Experimental Medicine and Biology. Springer, Cham., 1152.
Duncan, J. L., Cederbom, G. J., Champaign, J. L., Smetherman, D. H., King, T. A., Farr, G. H., Waring, A. N., Bolton, J. S., & Fuhrman, G. M. (2000). Benign diagnosis by image-guided core-needle breast biopsy. American Surgeon, 66(1), 5–10.
Faruk, T., Islam, M. K., Arefin, S., & Haq, M. Z. (2015). The Journey of Elastography: Background, Current Status, and Future Possibilities in Breast Cancer Diagnosis. Clinical Breast Cancer, 15(5), 313–324. https://doi.org/10.1016/j.clbc.2015.01.002
Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D. M., Forman, D., & Bray, F. (2015). Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer, 136(5), E359–E386. https://doi.org/10.1002/ijc.29210
Gkali, C. A., Chalazonitis, A. N., Feida, E., Sotiropoulou, M., Giannos, A., Tsigginou, A., & Dimitrakakis, C. (2015). Breast elastography: How we do it. Ultrasound Quarterly, 31(4), 255–261. https://doi.org/10.1097/RUQ.0000000000000180
Graziano, L., Bitencourt, A., Cohen, M., Guatelli, C., Poli, M., Souza, J., & Marques, E. (2017). Elastographic Evaluation of Indeterminate Breast Masses on Ultrasound. Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 39(02), 072–079. https://doi.org/10.1055/s-0036-1597753
INCA. (2019). Incidência do Câncer no Brasil. Estimativa 2020, Rio de Janeiro.
Lee, J. H., Kim, S. H., Kang, B. J., Choi, J. J., Jeong, S. H., Yim, H. W., & Song, B. J. (2011). Role and clinical usefulness of elastography in small breast masses. Academic Radiology, 18(1), 74–80. https://doi.org/10.1016/j.acra.2010.07.014
Lehman, C. D., Lee, C. I., Loving, V. A., Portillo, M. S., Peacock, S., & Demartini, W. B. (2012). Accuracy and value of breast ultrasound for primary imaging evaluation of symptomatic women 30-39 years of age. American Journal of Roentgenology, 199(5), 1169–1177. https://doi.org/10.2214/AJR.12.8842
Levy, L., Suissa, M., Chiche, J., Teman, G., & Martin, B. (2007). BIRADS ultrasonography. Eur J Radiol., 61(2), 202–211. https://doi.org/10.1016/j.ejrad.2006.08.035
Mercado, C. L. (2014). BI-RADS Update. Radiologic Clinics of North America, 52(3), 481–487. https://doi.org/10.1016/j.rcl.2014.02.008
Ministério da Saúde, I. (2019). Estimativa 2020 Incidência de Câncer no Brasil.
Myers, E. R., Moorman, P., Gierisch, J. M., Havrilesky, L. J., Grimm, L. J., Ghate, S., Davidson, B., Mongtomery, R. C., Crowley, M. J., McCrory, D. C., Kendrick, A., & Sanders, G. D. (2015). Benefits and harms of breast cancer screening: A systematic review. JAMA - Journal of the American Medical Association, 314(15), 1615–1634. https://doi.org/10.1001/jama.2015.13183
Nascimento, J. H. R. do, Silva, V. D. da, & Maciel, A. C. (2010). Acurácia dos achados mamográficos do câncer de mama: correlação da classificação BI-RADS e achados histológicos. Radiologia Brasileira, 43(2), 91–96. https://doi.org/10.1590/s0100-39842010000200008
Roveda Junior, D., Piato, S., Oliveira, V. M. de, Rinaldi, J. F., Ferreira, C. A. P., & Fleury, E. de C. F. (2007). Valores preditivos das categorias 3, 4 e 5 do sistema BI-RADS em lesões mamárias nodulares não-palpáveis avaliadas por mamografia, ultra-sonografia e ressonância magnética. Radiologia Brasileira, 40(2), 93–98. https://doi.org/10.1590/s0100-39842007000200006
Scheel, J. R., Lee, J. M., Sprague, B. L., Lee, C. I., & Lehman, C. D. (2015). Screening ultrasound as an adjunct to mammography in women with mammographically dense breasts. American Journal of Obstetrics and Gynecology, 212(1), 9–17. https://doi.org/10.1016/j.ajog.2014.06.048
Silva, H. R., Costa, R. H. F., Neto, J. C. P., Júnior, C. A. A. de M., Pacheco, N. I., Brito, N. da S., Soares, F. C. dos S., Sousa, L. K. R. de, Reis, J. A. da S., Oliveira, J. E. de A., & Pessoa, G. T. (2020). Associação prevalência e fatores de risco entre obesidade e câncer de mama. Research, Society and Development, 9(3), e62932385. https://doi.org/10.33448/rsd-v9i3.2385
Spak, D. A., Plaxco, J. S., Santiago, L., Dryden, M. J., & Dogan, B. E. (2017). BI-RADS® fifth edition: A summary of changes. Diagnostic and Interventional Imaging, 98(3), 179–190. https://doi.org/10.1016/j.diii.2017.01.001
Stavros, A. T., Thickman, D., Rapp, C. L., Dennis, M. A., Parker, S. H., & Sisney, G. A. (1995). Solid breast nodules: Use of sonography to distinguish between benign and malignant lesions. Radiology, 196(1), 123–134. https://doi.org/10.1148/radiology.196.1.7784555
Torres-Tabanera, M., Cárdenas-Rebollo, J. M., Villar-Castaño, P., Sánchez-Gómez, S. M., Cobo-Soler, J., Montoro-Martos, E. E., & Sainz-Miranda, M. (2012). Análisis del valor predictivo positivo de las subcategorías BI-RADS®4: resultados preliminares en 880 lesiones. Radiologia, 54(6), 520–531. https://doi.org/10.1016/j.rx.2011.04.004
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Joizeanne Pedroso Pires Chaves; Ivan Luiz Pedroso Pires; Marcos Araújo Chaves Júnior; Priscila Favero
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
