The occurrence of tumors of the central nervous system in the state of Sergipe from 2008 to 2017




Neurology; Central Nervous System; Tumor.


Objectives: The main objective of the study is to determine the epidemiological profile of patients with CNS tumor in the State of Sergipe from 2008 to 2017 and through the results allow to understand its prevalence and the main types of these tumors in Sergipe, comparing the results with other Brazilian states and other countries and assisting future research regarding this thematic. Methods: This is a retrospective cross-sectional study that initially included 215 patients - who were later restricted to 132 - diagnosed with brain tumors. These data were tabulated and statistically analyzed using IBM® SPSS Statistics® 24 and Microsoft® Excel® 2016 and then correlated. Results: The highest prevalence of CNS tumors was found in female patients, adults (mainly between 51 and 70 years old), Afro-Americans and married individuals. The largest amount of cases was found through the years 2014 and 2015. The most prevalent type of tumor in this study was glioma, followed by meningioma. Conclusion: This research evaluated whether social demographic factors of the CNS tumors patients in Sergipe were comparable to the literature. Our findings were similar to previus published data, with the exception of race and sex, as the prevalence varied accordingly to local populations in each study. The autors believe this study may constitute a foundation for future epidemiological studies in this topic.


American Cancer Society. (2018). Key Statistics for Brain and Spinal Cord Tumors. AMERICAN CANCER SOCIETY.

Australian Institute of Health and Welfare. (2014). Brain Cancer in Australia.

Baldi, I., Gruber, A., Alioum, A., Berteaud, E., Lebailly, P., Huchet, A., Tourdias, T., Kantor, G., Maire, J. P., & Vital, A. (2011). Descriptive epidemiology of CNS tumors in France: results from the Gironde Registry for the period 2000–2007. Neuro-Oncology, 13(12), 1370–1378.

Chakrabarti, I., Cockburn, M., Cozen, W., Wang, Y., & Preston‐Martin, S. (2005). A population‐based description of glioblastoma multiforme in Los Angeles County, 1974–1999. Cancer: Interdisciplinary International Journal of the American Cancer Society, 104(12), 2798–2806.

Deltour, I., Johansen, C., Auvinen, A., Feychting, M., Klaeboe, L., & Schüz, J. (2009). Time trends in brain tumor incidence rates in Denmark, Finland, Norway, and Sweden, 1974–2003. Journal of the National Cancer Institute, 101(24), 1721–1724.

Fisher, J. L., Schwartzbaum, J. A., Wrensch, M., & Wiemels, J. L. (2007). Epidemiology of brain tumors. Neurologic Clinics, 25(4), 867–890.

García Sánchez, S., & Solís Alfonso, L. (2010). Coincidencia de la tomografía computadorizada monocorte con el examen anatomopatológico posquirúrgico en el diagnóstico de los tumores intracraneales primarios. Revista Cubana de Medicina Militar, 39(2), 125–133.

Giordana, M. T., Schiffer, P., Lanotte, M., Girardi, P., & Chio, A. (1999). Epidemiology of adult medulloblastoma. International Journal of Cancer, 80(5), 689–692.

Goodenberger, M. L., & Jenkins, R. B. (2012). Genetics of adult glioma. Cancer Genetics, 205(12), 613–621.

IBGE. (2017). Distribuição da população por cor ou raça, Brasil 2012 – 2016.

INCA. (2016). Estimativa 2016 - Incidência de Câncer no Brasil.

INCA. (2019). Informações do Registro de Câncer de Base Populacional.

INCA. (2020). Estimativa 2020 - Incidência de Câncer no Brasil.

Japan, C. of B. T. R. of. (2017). Report of brain tumor registry of Japan (2005–2008). Neurol Med Chir (Tokyo), 57(Suppl 1), 9–102.

Kerr, D. J., Haller, D. G., van de Velde, C. J. H., & Baumann, M. (2016). Oxford textbook of oncology. Oxford University Press.

Kohler, B. A., Ward, E., McCarthy, B. J., Schymura, M. J., Ries, L. A. G., Eheman, C., Jemal, A., Anderson, R. N., Ajani, U. A., & Edwards, B. K. (2011). Annual report to the nation on the status of cancer, 1975–2007, featuring tumors of the brain and other nervous system. Journal of the National Cancer Institute, 103(9), 714–736.

Krishnatreya, M., Kataki, A. C., Sharma, J. D., Bhattacharyya, M., Nandy, P., & Hazarika, M. (2014). Brief descriptive epidemiology of primary malignant brain tumors from North-East India. Asian Pac J Cancer Prev, 15(22), 9871–9873.

Larjavaara, S., Mäntylä, R., Salminen, T., Haapasalo, H., Raitanen, J., Jääskeläinen, J., & Auvinen, A. (2007). Incidence of gliomas by anatomic location. Neuro-Oncology, 9(3), 319–325.

Longo, D. L., Fauci, A. S., Kasper, D. L., Hauser, S. L., Jameson, J. L., & Loscalzo, J. (2012). Harrison’s principles of internal medicine 18E Vol 2 EB. McGraw Hill Professional.

Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007). The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathologica, 114(2), 97–109.

Mendes, G. A., Ongaratti, B. R., & Pereira-Lima, J. F. S. (2014). Epidemiologia de uma série de tumores primários do sistema nervoso central. Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, 33(04), 279–283.

NCI. (2014). Adult Brain Tumors Treatment.

Ostrom, Q. T., Gittleman, H., Fulop, J., Liu, M., Blanda, R., Kromer, C., Wolinsky, Y., Kruchko, C., & Barnholtz-Sloan, J. S. (2015). CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro-Oncology, 17(suppl_4), iv1–iv62.

Preston-Martin, S., & Mack, W. J. (1996). Neoplasms of the nervous system. Cancer epidemiology and prevention. New York: Oxford University Press.

Radhakrishnan, K., Mokri, B., Parisi, J. E., O’Fallon, W. M., Sunku, J., & Kurland, L. T. (1995). The trends in incidence of primary brain tumors in the population of Rochester, Minnesota. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society, 37(1), 67–73.

Ries, L. A. G., Eisner, M. P., Kosary, C. L., Hankey, B., Miller, B., Clegg, L., Mariotto, A., Feuer, E., & Edwards, B. (2011). SEER Cancer Statistics Review, 1975-2001, National Cancer Institute. Bethesda, MD; 2004. Available at: Seer. Cancer. Gov/Csr/1975-2001.

Shibui, S. (2014). Report of brain tumor registry of Japan (2001–2004). Neurologia Medico-Chirurgica, 54(suppl. 1).

Torres, L. F. B., Almeida, R., Avila, S., Alessi, S., & Freitas, R. (1990). Brain tumours in south Brazil a retrospective study of 438 cases. Arquivos de Neuro-Psiquiatria, 48(3), 279–285.

Valiente, M., Ahluwalia, M. S., Boire, A., Brastianos, P. K., Goldberg, S. B., Lee, E. Q., Le Rhun, E., Preusser, M., Winkler, F., & Soffietti, R. (2018). The evolving landscape of brain metastasis. Trends in Cancer, 4(3), 176–196.

Wiemels, J., Wrensch, M., & Claus, E. B. (2010). Epidemiology and etiology of meningioma. Journal of Neuro-Oncology, 99(3), 307–314.

Wigertz, A., Lönn, S., Hall, P., & Feychting, M. (2010). Non-participant characteristics and the association between socioeconomic factors and brain tumour risk. Journal of Epidemiology & Community Health, 64(8), 736–743.

Wild, C. P., Stewart, B. W., & Wild, C. (2014). World cancer report 2014. World Health Organization Geneva, Switzerland.



How to Cite

Sandes , V. dos A. ., Dantas, R. L. ., Porto, R. L. S. ., Reis , F. F. P. ., Sousa , D. S. de ., Lima, S. O. ., Marcena, S. L. S. ., & Reis, F. P. (2020). The occurrence of tumors of the central nervous system in the state of Sergipe from 2008 to 2017. Research, Society and Development, 9(11), e3439119673.



Health Sciences