Hepatitis B vaccination in people living with HIV in the State of Piauí, Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v10i6.11459

Keywords:

Immunization; Hepatitis B; HIV; AIDS.

Abstract

Hepatitis B (HB) is responsible for several conditions such as cirrhosis and hepatocellular carcinoma. Prevention through vaccination is essential for people living with HIV, since this group has a higher rate of progression to the chronicity of the disease. The objective of the study was to analyze vaccination coverage against HB virus in the state of Piauí, through an epidemiological serum study of seropositive patients registered in the Laboratory Examination Control System (SISCEL) of the Central Laboratory of Public Health of Piauí in the year 2010. Data from 569 HIV-positive people were analyzed, with epidemiological variables such as age, color, education and serological markers for hepatitis B. The viral marker for hepatitis B, anti-HBs, was also determined. The findings were filtered and organized to compare the frequencies of anti-HBs titers among HIV-positive individuals. Seroconversion values ​​for anti-HBs were observed in only 39.7% of the participants, which confirms that lower rates of production of these antibodies occur in patients immunocompromised by HIV. According to the anti-HBs titles, key vulnerability behaviors were observed that make patients susceptible to infection, with emphasis on: family income and education, which point to the need to implement public policies that serve the population less favored.

Author Biography

Evaldo Hipólito de Oliveira, Universidade Federal do Piauí

Possui graduação em Farmácia pela Universidade Federal da Paraíba (1990), graduação em Farmácia e Bioquímica pela Universidade Federal da Paraíba (1991), graduação em Direito pela Universidade Federal do Piauí (1999), Doutorado em Biologia de Agentes Infecciosos e Parasitários (2010), mestrado em Administração pela Universidade Federal da Paraíba (2002), especialização em Vigilância Sanitária e Epidemiológica (1997) e Citologia Clínica (2005). Foi Diretor do Laboratório Central de Saúde Pública do Estado do Piauí-LACEN-PI (2003 a 2007). Atualmente é professor Associado da Universidade Federal do Piauí de microbiologia clínica e imunologia clínica (1994). Tem experiência na área de Farmácia (Interdisciplinaridade), atuando principalmente nos seguintes temas: análises clínicas ( bacteriologia, virologia, imunologia, citologia e hematologia ) e Vírus Linfotrópico de Células T Humanas-1/2-HTLV-1/2, HIV, HBV e HCV (Epidemiologa, Imunologia e Análise Molecular).

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Published

21/05/2021

How to Cite

OLIVEIRA, E. H. de .; SILVA, A. C. dos S. .; RÊGO, I. V. .; LOPES, T. B. de C. .; ROCHA , K. G. L. .; GUIMARÃES, L. O. .; OLIVEIRA, A. C. .; OLIVEIRA, M. M. de .; MOURA, Y. de S. . Hepatitis B vaccination in people living with HIV in the State of Piauí, Brazil. Research, Society and Development, [S. l.], v. 10, n. 6, p. e7010611459, 2021. DOI: 10.33448/rsd-v10i6.11459. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/11459. Acesso em: 18 apr. 2024.

Issue

Section

Health Sciences