Analysis of oral health and salivary biochemical parameters of women with anorexia and bulimia nervosa
DOI:
https://doi.org/10.33448/rsd-v10i3.12971Keywords:
Anorexia; Bulimia; Eating disorders; Oral manifestations; Saliva.Abstract
Análisis de parámetros bioquímicos de salud bucal y salival de mujeres con anorexia y bulimia nerviosa
Objective: The aim of this study was to analyze the association between caries, dental erosion and salivary biochemical profile of women with anorexia and bulimia, comparing them with a control group. Methods: The participants were women from the Eating Disorders Program of the Mental Health Clinic. We evaluated caries and dental erosion and collected stimulated saliva samples for the analyses of salivary flow, phosphor, calcium, acid and alkaline phosphatase, amylase, FRAP and uric acid. Data were expressed as means and standard deviations and were analysed using Mann-Whitney test with p<0.05 regarded as significant. Results: 13 women with anorexia and bulimia participated in the study, with an mean age of 28.9 years, and 15 comprised the control group. The DMFT index was 15.5 for the case group and 4.0 for the control group. Erosion was found mostly on the palatal/lingual surface and on incisor teeth of case group. Most biochemical analyzes showed a significant difference between the two groups. Conclusion: We concluded that, in patients with anorexia and bulimia, due to a decreased salivary flow and self-induced vomiting habits, there is an increase in the caries and dental erosion index, as well as salivary changes.
References
American Psychological Association – APA. (2014). Diagnostic and statistical manual of mental disorders. (5th ed.): American Psychological Association
Antunes, K. T., Amaral, C. F., & Balbinot, C. E. A. (2007). Anorexia e bulimia nervosa: complicações bucais e o papel do cirurgião-dentista frente a transtornos alimentares. Disc Scientia, 8:159-167
Assumpção, C. L., & Cabral, M. D. (2002) Complicações clínicas da anorexia nervosa e bulimia nervosa. Rev Bras Psiquiatr, 24:29-33
Ayres, M., Ayres Júnior, M., Ayres, D. L., & Santos, A. S. (2007). BioEstat 5.0: statistics applications in the areas of biomedical sciences [computer program]: Ong Mamieraua, Portuguese
Barboza, A., Morais, P. D., Alves, M. V. A., Carneiro, D. T. O., & Moura, S. A. B. (2011). Participação do cirurgião-dentista no diagnóstico e tratamento interdisciplinar dos transtornos alimentares. Int J Dent, 10:32-37
Benzie, F. F. I., & Strain, J. J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Analytical biochemistry, 239:70-76
Brandt, L. M. T., Fernandes L. H. F., Aragão, A. S., Aguiar, Y. P.C., Auad, S. M., Castro, R. D., et al. (2017). Relationship between Risk Behavior for Eating Disorders and Dental Caries and Dental Erosion. The Scientific World Journal, 2017:1-7.
Carvalho, M. B. D., Val, A. C., Ribeiro, M. M. F., & Santos, L. G. D. (2016). Therapeutic itineraries of individuals with symptoms of anorexia and bulimia. Cienc saúde coletiva, 21:2463-2474.
Chaves-Neto, A. H., Sassaki, K. T., & Nakmune, C. M. S. (2011). Protein phosphatase activities in the serum and saliva of healthy children. RPG. Rev Pos Grad, 18:90-95
Cruz, A., Oliveira, C., Sá, P., & Corassin, C. H. (2017). Química, Bioquímica, Análise Sensorial e Nutrição no Processamento de Leite e Derivados: Coleção Lácteos, Elsevier Brasil
DeBate, R. D., Tedesco, L. A., & Kerschbaum, W. E. (2005). Knowledge of oral and physical manifestations of anorexia and bulimia nervosa among dentists and dental hygienists. J Dent Educ, 69:346-354
Devlin, T. M. (2011). Manual de Bioquímica com Correlações Clínicas, (7a ed.,) Ed. Blucher
Frydrych, A. M., Davies, G. R., & McDermott, B. M. (2005). Eating disorders and oral health: a review of the literature. Aust Dent J, 50:6-15.
Gomes, R., & Silva, L. (2010). Desordens alimentares e perfeccionismo: um estudo com atletas portuguesas. Psic Rev, 16:469- 489
Hartree, E. F. (1972). Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal. Biochem, 48:422-427
Howe, L., & Elmslie, R. G. (1971). Stability of amylase in serum from patients with pancreatitis. Aust J Exp Biol Med Sci, 49:513-515
Jarvinen, V. K., Rytomaa, I. I., & Heinonen, O. P. (1991). Risk Factors in Dental Erosion. Journal of Dental Research, 70:942–947.
Johansson, A. K., Norring, C., Unell, L., & Johansson, A. (2015). Eating disorders and biochemical composition of saliva: a retrospective matched case–control study. Eur J Oral Sci, 123:158-164.
Kessler, R. C., Berglund, P. A., Chiu, W. T., Deitz, A. C., Hudson, J. I., Shahly, V., et al. (2013). The prevalence and correlates of binge eating disorder in the World Health Organization World Mental Health Surveys. Biol Psychiatry, 73:904-914.
Kunde, F. R., Mitinguel, L. H., Bellato, A., & Moreira, M. A. (2017). Perimólise em paciente portadores de bulimia nervosa do tipo purgativa: Revisão de Literatura. Conv Inter, 13:1-8.
López, M. E., Colloca, M. E., Páez, R. G., Schallmach, J. N., Koss, M. A., & Chervonagura, A. (2003). Salivary characteristics of diabetic children. Braz Dent J, 14:26–31.
Lourenço, M., Azevedo, A., Brandão, I., & Gomes, P. S. (2018). Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior. Clin Oral Investig, 22:1915–1922.
Marshall, T. A. (2018). Dietary assessment and counseling for dental erosion. The Journal of the American Dental Association, 149:148-152.
Navarro, V., Matoba Júnior, F., Tedeschi Filho, W., & Queirós, A. M. (2011). Desordens Alimentares: aspectos de interesse na odontologia. Rev Gauch Odontol, 59:15-18
Neel, E. A. A., Aljabo, A., Strange, A., Ibrahim, S., Coathup, M., Young, A. M., et al. (2016). Demineralization – remineralization dynamics in teeth and bone. Int J Nanomedicine, 11:4743-4763.
Panico, R., Piemonte, E., Lazoz, J., Gilligan, G., Zampini, A., & Lanfranchi, H. (2017). Oral mucosal lesions in Anorexia Nervosa, Bulimia Nervosa and ADNOS. J of Psic Res, 98:178-182.
Prakash, A. R., Indupuru, K., Sreenath, G., Kanth, M. R., Reddy, A. V., & Indira, Y. (2016). Salivary alkaline phosphatase levels speak about association of smoking, diabetes and potentially malignant diseases??? J Oral Maxillofac Pathol, 20:66-70.
Rytömaa, I., Järvinen, V., Kanerva, R., & Heinonen, O. P. (1998). Bulimia and tooth erosion. Acta Odontol Scand, 56:36-40.
Saito, S., & Kizu, K. (1959). Phosphatase activity in whole and parotid saliva and its relationship to dental caries. J Dent Res, 38:500-505.
Santos, R. D., Souza, R. O., Dias, L. B., Ribas, T. B., Oliveira, L. C.F., Sumida, D. H., et al. (2018). The effects of storage time and temperature on the stability of salivary phosphatases, transaminases and dehydrogenase. Arch Oral Bio, 85:160-165.
Scheutzel, P. (1996). Etiology of dental erosion-intrinsic factors. European Journal of Oral Sciences, 104:178-190.
Scheutzel, P., & Gerlach, U. (1991). Isoenzimas alfa-amilase no soro e na saliva de pacientes com anorexia e bulimia nervosa. Gastroenterologia, 29: 339–345
Schutz, A. K., Utumi, A. N., Ignácio, S. A., Brancher, J. A., & Fregoneze, A. P. (2017). Análise sialométrica em indivíduos portadores da síndrome de Down. Arch of Oral Res, 9:165-170.
Silva, A., Fraga, J. C., Costa, A. M., Dias, F., & Brito, I. (2017). Juvenile recurrent parotiditis not always what it seems. Birth Growth Med J, 22:25-29.
Smith, B. G. N., & Knight, J. K. (1984). An índex for measuring the wear of teeth. Br Dent J 156:435-438
Sophia, K., Suresh, S., Sudhakar, U., Jayakumar, P., & Mathew, D. (2017). Comparative analysis of salivary alkaline phosphatase in post menopausal women with and without periodontitis. J Cli Diagn Res, 11:ZC122–ZC124.
Swanson, S. A., Crow, S. J., Grange, D. L., Swendsen, J., & Merikangas, K. R. (2011). Prevalence and correlates of eating disorders in adolescents: results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry, 68:714-723.
Von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gotzche, P. C., Vandenbroucke, J. P. (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med, 4:e296.
World Health Organization. (1999). Oral Health Surveys: Basic Methods. (4th ed,) Geneva
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