Chemical profile and larvicidal activity of essential oil obtained from the leaves of Plectranthus amboinicus (Lour.) Spreng
DOI:
https://doi.org/10.33448/rsd-v10i4.13846Keywords:
Essential oils; Larvicide; Chemical constituents.Abstract
This study aimed to determine the chemical constituents and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against larvae of the Aedes aegypti mosquito. The essential oil (EO) was extracted by hydrodistillation at 100 ° C for 3 hours. The chemical composition was obtained by Gas Chromatography coupled to Mass Spectrometry (GC / MS). To assess larvicidal activity, Aedes aegypti larvae were subjected to EO solutions in concentrations of 10-100 mg L-1, where larval mortality was assessed and the LC50 was determined using the Probit method. The main chemical constituent found in the EO was carvacrol, which is considered to be very promising for pharmaceutical synthesis. The EO showed larvicidal activity with an LC50 of 28.52 mg L-1. According to the results found, it was possible to evaluate that the analyzed EO is composed of substances that have an efficient larvicidal effect against Aedes aegypti, thus encouraging its potential for application.
References
Alfaia, D. P. S. (2016). Phytochemical evaluation, cytotoxic and antimicrobial analysis of the crude ethanolic extract of the leaves of Annona muricata L. (Annonaceae). Amazon Biota (Biote Amazonie, Biota Amazonia, Amazonian Biota), 6 (1), 26-30.
Alitonou, G. A., Noudogbessi, J. P., Sessou, P., Tonouhewa, A., Avlessi, F., Menut, C., & Sohounhloue, D. C. (2012). Chemical composition and biological activities of essential oils of Pimenta racemosa (Mill.) JW Moore. from Benin. Int J Biosci, 2(9), 1-12.
Bhatt, S., Gething, P. W., Brady, O. J., Messina, J. P., Farlow, A. W., Moyes, C. L., & Myers, M. F. (2013). The global distribution and burden of dengue. Nature, 496(7446), 504-507.
Bermúdez, A., Oliveira-Miranda, M. A., & Velázquez, D. (2005). La investigación etnobotánica sobre plantas medicinales: una revisión de sus objetivos y enfoques actuales. Interciencia, 30(8), 453-459.
Brasil (2019). Boletim Epidemiologico: Monitoramento dos casos de arboviroses urbanas transmitidas pelo Aedes (dengue, chikungunya e Zika) até a Semana Epidemiológica 12 de 2019 e Levantamento Rápido de Índices para Aedes aegypti (LIRAa). Secretaria de Vigilância em Saúde :Ministério da Saúde.
Carvalho, M. D. S. L. D., Caldas, E. D., Degallier, N., Vilarinhos, P. D. T. R., Souza, L. C. K. R. D., Yoshizawa, M. A. C., & Oliveira, C. D. (2004). Suscetibilidade de larvas de Aedes aegypti ao inseticida temefós no Distrito Federal. Revista de Saúde Pública, 38, 623-629.
Crivelenti, L. Z., Guilherme, L. C., Morelli, S., & Borin, S. (2010). Toxicidade do inseticida Organofosforado Abate® em alevinos de Poecilia reticulata. Embrapa Meio-Norte-Artigo em periódico indexado (ALICE).
De Freitas Bezerra, R. D. C., de Oliveira Neto, F. B., da Silva, F. F. M., Bertini, L. M., & Alves, L. A. (2017). Seasonal effect in essential oil composition and antioxidant activity of Plectranthus amboinicus leaves. Bioscience Journal, 33(6).
De Souza Duarte, L., Pereira, MTM, Pascoal, VD Á. B., & Pascoal, ACRF (2020). Gênero Campomanesia - uma revisão da literatura de metabólitos secundários não voláteis, fitoquímica, uso popular, atividades biológicas e toxicologia. Eclética Química Journal , 45 (2), 12-22.
Dias, C. N., & Moraes, D. F. C. (2014). Essential oils and their compounds as Aedes aegypti L.(Diptera: Culicidae) larvicides. Parasitology research, 113(2), 565-592.
Dos Santos, A. B. D. S., Everton, G. O., Júnior, R. G. D. O. C., Rosa, P. V. S., Pereira, A. P. M., dos Santos Souza, L., ... & Mouchrek Filho, V. E. (2020). Óleos essenciais de Cinnamomum zeylanicum Blume e Plectranthus amboinicus (lour.) Spreng como agentes larvicidas frente as larvas do Aedes aegypti. Brazilian Journal of Development, 6(4), 22355-22369.
Finney, D. J. (1952). Probit analysis: a statistical treatment of the sigmoid response curve. Cambridge university press, Cambridge.
Forattini, O. P. (1962). Entomologia medica vol. I Faculdade de Higiene e Saude Publica. Sao Paulo, Brazil. pp.
Gomes, P. R. B., Oliveira, M. B., de Sousa, D. A., da Silva, J. C., Fernandes, R. P., Louzeiro, H. C., ... & Fontenele, M. A. (2019). Larvicidal activity, molluscicide and toxicity of the essential oil of Citrus limon peels against, respectively, Aedes aegypti, Biomphalaria glabrata and Artemia salina. Eclética Química Journal, 44(4), 85-95.
Huang, H. T., Lin, C. C., Kuo, T. C., Chen, S. J., & Huang, R. N. (2019). Phytochemical composition and larvicidal activity of essential oils from herbal plants. Planta, 250(1), 59-68.
Jayaraman, M., Senthilkumar, A., & Venkatesalu, V. (2015). Evaluation of some aromatic plant extracts for mosquito larvicidal potential against Culex quinquefasciatus, Aedes aegypti, and Anopheles stephensi. Parasitology research, 114(4), 1511-1518.
Kim, E., Oh, C. S., Koh, S. H., Kim, H. S., Kang, K. S., Park, P. S., ... & Park, I. K. (2016). Antifungal activities after vaporization of ajowan (Trachyspermum ammi) and allspice (Pimenta dioica) essential oils and blends of their constituents against three Aspergillus species. Journal of EssEntial oil rEsEarch, 28(3), 252-259.
Matos, F. J. A. (2009). Introdução à Fitoquímica Experimental, 3ª. Edição, UFC, Fortaleza.
Menezes Filho, A. C. P., & Souza Castro, C. F. (2019). Phytochemical classes of secondary metabolites in foliar ethanolic extracts of species of the brazilian cerrado. Revista Saúde & Ciência Online, 8 (1), 45-61.
Minott, D. A., & Brown, H. A. (2007). Differentiation of fruiting and non-fruiting Pimenta dioica (L.) Merr. trees based on composition of leaf volatiles. Journal of Essential Oil Research, 19(4), 354-357.
Mirzahosseini, S. M., Noori, S. A. S., Amanzadeh, Y., Javid, M. G., & Howyzeh, M. S. (2017). Phytochemical assessment of some native ajowan (Therachyspermum ammi L.) ecotypes in Iran. Industrial crops and products, 105, 142-147.
Monzote, L., Scherbakov, AM, Scull, R., Gutiérrez, YI, Satyal, P., Cos, P., ... & Setzer, WN (2020). Avaliação farmacológica do óleo essencial do quimiotipo carvacrol de Plectranthus amboinicus em cultivo em Cuba. Natural Product Communications , 15 (10), 1934578X20962233.
Paramasivam, D., Balasubramanian, B., Park, S., Alagappan, P., Kaul, T., Liu, W., & Pachiappan, P. (2020). Phytochemical profiling and biological activity of Plectranthus amboinicus (Lour.) mediated by various solvent extracts against Aedes aegypti larvae and toxicity evaluation. Asian Pacific Journal of Tropical Medicine, 13(11), 494.
Prophiro, J. S., Silva, O. S., Luna, J. E. D., Piccoli, C. F., Kanis, L. A., & Silva, M. A. N. da. (2011). Aedes aegypti and Aedes albopictus (Diptera: Culicidae): coexistence and susceptibility to temephos, in municipalities with occurrence of dengue and differentiated characteristics of urbanization. Revista da Sociedade Brasileira de Medicina Tropical, 44(3), 300-305.
Santos, N. O. D., Mariane, B., Lago, J. H. G., Sartorelli, P., Rosa, W., Soares, M. G., ... & Pascon, R. C. (2015). Assessing the chemical composition and antimicrobial activity of essential oils from Brazilian plants—Eremanthus erythropappus (Asteraceae), Plectrantuns barbatus, and P. amboinicus (Lamiaceae). Molecules, 20(5), 8440-8452.
Silva, H. H. G. D., Silva, I. G. D., Elias, C. N., Lemos, S. P. S., & Rocha, A. P. (1995). Idade fisiológica dos ovos de aedes (stegomyia) aegypti (Linnaeus, 1762)(diptera, culicidae).
Silva, W. J. D. (2006). Atividade larvicida do óleo essencial de plantas existentes no estado de Sergipe contra Aedes aegypti Linn.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Ana Patrícia Matos Pereira; Thércia Gabrielle Teixeira Martins; Mariana Oliveira Arruda; Andressa Almeida Santana Dias; Laiane Araujo da Silva Souto; Ari Pereira de Araújo Neto; Liane Batista da Cruz Soares ; Ana Maria Almeida Silva Carvalho; Ricardo Teixeira de Sousa; Carlos Eduardo Pereira Conceição ; Francilidia Oliveira Vitorino de Assunção Conceição ; Gustavo Oliveira Everton
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
