Epidemiological characterization of mortality from Chagas disease in Brazil from 2010 to 2019

Authors

DOI:

https://doi.org/10.33448/rsd-v10i10.19096

Keywords:

American trypanosomiasis; Chagas Disease; Neglected tropical diseases.

Abstract

Chagas disease or American trypanosomiasis is an infection caused by the protozoan Trypanosoma cruzi transmitted by a triatomine insect. In infected individuals, this disease can compromise the heart or gastrointestinal tract and is potentially fatal. It is estimated that approximately 6 to 7 million people are infected with T. cruzi worldwide. Chagas disease represents a challenge mainly for public health in Latin America, where it is endemic in 21 countries, including Brazil. Therefore, this research aims to verify the mortality from Chagas Disease in Brazil during the years 2010 to 2019, through a cross-sectional descriptive study, using population-based data from the Mortality Information System (SIM) of the Ministry of Brazilian Health. During the analysis, it was found that in the period evaluated, 45,409 deaths were registered in the SIM in the five Brazilian regions. Regarding the reported cases, the predominant sociodemographic characteristics were: male (54.38%), aged between 70 and 79 years (28.02%), brown race/color (42.09%), and education < 8 years (45.47%). The results obtained indicate a relation between social vulnerability and the involvement of Chagas disease. In addition, it was evident that, despite advances, the number of deaths registered in Brazil remains at a very high level. The SIM proved to be an important tool for conducting epidemiological studies, however, some limitations were observed regarding the quality of the records, evidencing some flaws.

References

Amorim, D. S. & Costa, M. S. F. (2021) Tendência da mortalidade por doença de Chagas na Bahia: Entre os anos de 2008 a 2018. Research, Society and Development, 10 (5).

Barreto., P. G. S et al (2021) Descrição de eventos adversos a medicamentos em pacientes hospitalizados com a doença de Chagas. Revista Multidisciplinar Em Saúde, 2 (1), 58.

Bern, C et al (2019) Chagas disease in the United States: a public health approach. Clinical microbiology reviews, 33 (1).

Brito, A. C. O et al (2021) Um Doenças Negligenciadas: Doença de Chagas e os aspectos atuais do tratamento. Revista de Ensino, Ciência e Inovação em Saúde, 2 (1), 9-17.

Costa, M. M. R et al (2018) Doença de chagas: tendência epidemiológica por regiões do Brasil. Brazilian Journal of Health Review, 1 (1), 252-259.

Cordeiro, T. A. R et al (2021) Electrochemical biosensors for neglected tropical diseases: A review. Talanta.

Confortin, S. C et al (2019) Mortalidade prematura pelas principais doenças crônicas não transmissíveis nos estados do Brasil. Revista Brasileira de Enfermagem, 72, 1588-1594.

Dias, J. C. P et al (2016) II Consenso Brasileiro em Doença de Chagas, 2015. Epidemiol. Serv. Saúde, Brasília, 25, 7-86.

Echalar, J-C et al (2021) Age-related anomalies of electrocardiograms in patients from areas with differential Seroprevalence of Chagas disease in Southern Bolivia." Parasite Epidemiology and Control. 13, e00204.

Echeverría, L. E et al (2021) Coagulation disorders in Chagas disease: A pathophysiological systematic review and meta-analysis. Thrombosis Research, 201, 73-83.

Felipe, A. G. B et al (2020) Doença de chagas: Análise de mortalidade na região Centro-Oeste do Brasil (2008 a 2017). Brazilian Journal of Health Review, v. 3 (6), 16102-16107.

Franco-Paredes, C et al (2020) A deadly feast: Elucidating the burden of orally acquired acute Chagas disease in Latin America–Public health and travel medicine importance. Travel medicine and infectious disease.

Freitas, M. J. C et al (2019) Cardiopatia chagásica em pacientes idosos. Brazilian Journal of Health Review, 2 (4), 3283-3285.

IBGE. Instituto Brasileiro de Geografia e Estatística. Brasil. 2020. Disponível em: https://www.ibge.gov.br/cidades-e-estados.html. Acesso em: 18 jul. 2020.

Ikedionwu, C et al (2020) Trends and associated characteristics for Chagas disease among women of reproductive age in the United States, 2002 to 2017. Parasite Epidemiology and Control.

Ledezma, A. P et al (2020) Mixed infections by different Trypanosoma cruzi discrete typing units among Chagas disease patients in an endemic community in Panama. PloS one, 15 (11).

Lima-Costa, M. F et al (2010) Chagas disease and mortality in old age as an emerging issue: 10 year follow-up of the Bambuí population-based cohort study (Brazil). International Journal of Cardiology, 145, 362-363.

Lima, E. A. N et al (2020) T. A. Análise das produções científicas relacionadas à Doença de Chagas. Brazilian Archives of Health and Environment, 1 (1), 16-24.

Luna, E. J. A. & Campos, S. R. S. L. C. (2020) O desenvolvimento de vacinas contra as doenças tropicais negligenciadas. Cadernos de Saúde Pública.

Martins-Melo, F. R et al (2019) Burden of Chagas disease in Brazil, 1990–2016: findings from the Global Burden of Disease Study 2016. International journal for parasitology, 49 (3-4), 301-310.

Martins-Melo, F. R et al (2021) Levels and trends in Chagas disease-related mortality in Brazil, 2000–2019. Acta Tropica.

Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Doença de Chagas: 14 de abril –Dia Mundial. Bol Epidemiol. 2020. Disponível em: http://www.saude.gov.br/boletins-epidemiologicos.

Neves, D. P et al (2016) Parasitologia Humana. 13 ed. São Paulo: Editora Atheneu.

Porfírio, D. M et al (2020) Prevalência de Doença de Chagas em Idosos no Estado do Pará: Uma Análise Retrospectiva. Brazilian Journal of Health Review, 3 (4), 9142-9152.

Silva, A. P et al (2019) Doença de Chagas: Perfil de morbidade hospitalar na Região do Nordeste Brasileiro. Revista de Ciências da Saúde Nova Esperança, 17 (3), 08-17.

Silva, P. L. N et al (2021) Impacto do déficit de investimentos para o tratamento da doença de chagas no Brasil: revisão narrativa. Nursing (São Paulo), 24 (275), 5514-5529.

Silva, M. S et al. Internações e mortalidade de cirurgias otorrinolaringológicas nos estados brasileiros no período de 2011 a 2021. Research, Society and Development, 10 (8), e58910817678-e58910817678.

Souza, S. B et al (2021) Perfil epidemiológico da doença de Chagas aguda na região norte do Brasil no ano de 2015-2019. Revista Eletrônica Acervo Saúde,13 (7), 8200-8200.

WHO - WORLD HEALTH ORGANIZATION. Chagas disease - American trypanosomiasis (2021). Geneva: World Health Organization. Disponível em: https://www.who.int/health-topics/chagas-disease#tab=tab_1, Acesso em: 10 jul. 2019.

Published

20/08/2021

How to Cite

GONÇALVES , W. .; MATOS, D. F. .; PAZ, W. S. da .; SOUZA, J. V. de .; SANTOS, A. B. A. de S. .; SANTOS, M. G. M. dos .; OLIVEIRA , S. F. de .; SILVA, M. A. .; NUNES, M. L. A. .; MELO, R. L. B. .; RICARDO, M. F. F. .; SILVA, J. F. da .; BEZERRA, L. P. .; VARJÃO, M. T. dos S. .; BALBINO, R. dos S. .; SOUZA, L. L. A. de .; ARAÚJO, Q. M. dos S. .; ALMEIDA, D. H. de . Epidemiological characterization of mortality from Chagas disease in Brazil from 2010 to 2019. Research, Society and Development, [S. l.], v. 10, n. 10, p. e592101019096, 2021. DOI: 10.33448/rsd-v10i10.19096. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/19096. Acesso em: 22 nov. 2024.

Issue

Section

Health Sciences