Clinical effect of the use of probitics as an adjuvant to the non-surgical periodontal treatment of periodontitis: systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i14.21703

Keywords:

Periodontal diseases; Periodontal Diseases; Dental Scaling; Probiotics.; Dental scaling; Probiotics.

Abstract

The present study analyzed the effect of using probiotics as adjuncts to scaling and root planing (SRP) in the treatment of periodontits. A search was performed in the electronic databases PubMed and Cochrane, using randomized controlled clinical studies in English, published until February 2021, as inclusion criteria. The administration of probiotics as an adjunct to basic periodontal treatment reveals clinical benefits concentrated in the reduction of the inflammatory process, clinical attachment levels and reduction in the depth of periodontal pockets, in the plaque index and bleeding on probing. Thus, the decrease in periodontal pockets suggests a lower risk of progression of periodontal disease. The SRP + probiotic adjunct use suggests a beneficial effect in relation to clinical parameters, such as probing depth, clinical attachment levels and bleeding on probing, especially in relation to the reduction of residual periodontal pockets. However, there is a need for long-term clinical trials, with greater variety in the probiotic strains used, for a better understanding of the therapeutic role of probiotics in the treatment of periodontits.

References

Batchelor, P. (2014). Is periodontal disease a public health problem? Nat Publ Gr. 405–9.

Cobb, C. M. (2002). Clinical significance of non-surgical periodontal therapy: An evidence-based perspective of scaling and root planing. J Clin Periodontol. 29(SUPPL. 2):22–32.

Esteban-Fernández, A., Ferrer, M., Zorraquín-Peña, I., López-López, A., Moreno-Arribas, M., & Mira, A. (2019). In vitro beneficial effects of Streptococcus dentisani as potential oral probiotic for periodontal diseases. J Periodontol. 90(11):1346–55.

Guias mundiais da WGO. (2011). Probióticos e prebióticos.

Hao, Q., Dong, B., & Wu, T. (2015). Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. (2).

Ince, G., Gursoy, H., Ipçi, S., Cakar, G., Emekli-Alturfan, E., & Yilmaz, S. (2015). Clinical and Biochemical Evaluation of Lactobacillus Reuteri Containing Lozenges as an Adjunct to Non-Surgical Periodontal Therapy in Chronic Periodontitis. J Periodontol. 1–13.

Invernici, M., Salvador, S., Silva, P., Soares, M., Casarin, R., Palioto, D., Souza, S., Taba Júnior, M., Novaes Júnior, A., Furlaneto, F., & Messora, M. (2018). Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial. 1198–210.

Higgins, J., Altman, D., Gøtzsche, P., Jüni, P., Moher, D., Oxman, A., Savovic, J., & Schulz, K. (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 343(7829):1–9.

Mayanagi, G., Kimura, M., Nakaya, S., Hirata, H., Sakamoto, M., Benno, Y., & Shimauchi, H. (2009). Probiotic effects of orally administered Lactobacillus salivarius WB21-containing tablets on periodontopathic bacteria : a controlled, randomized clinical trial. (3):506–13.

Meenakshi, S. S., & Varghese, S. (2018). Adjunctive effect of probiotic (Lactobacillus casei Shirota) to scaling and root planing in the management of chronic periodontitis. 10(8):3–6.

Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew M., Shekelle, P., & Stewart, L. (2015). Preferred reporting items for systematic review and meta-analysis protocols ( PRISMA-P). 2015 statement. 1–9.

Pelekos, G., Ho, S., Acharya, A., Leung, W., & McGrath, C. (2019). A double-blind, paralleled-arm, placebo-controlled, randomized clinical trial of the effectiveness of probiotics as an adjunct in periodontal care. J Periodontol.

Ricoldi, M., Furlaneto, F., Oliveira, L., Teixeira, G., Pischiotini, J., Moreira, A., Ervolino, E., Oliveira, M., Bogsan, C., Salvador, S., & Messora, M. (2017). Effects of the probiotic Bifidobacterium animalis subsp. lactis on the non-surgical treatment of periodontitis. A histomorphometric, microtomographic and immunohistochemical study in rats. PLoS One. 12(6):1–15.

Scannapieco, F., & Gershovich, E. (2020). The prevention of periodontal disease — An overview. 9–13.

Tekce, M., Ince, G., Gursoy, H., Dirikan, S., Cakar, G., Kadir, T., & Yilmaz, S. (2015). Clinical and microbiological effects of probiotic lozenges in the treatment of chronic periodontitis: a 1-year follow-up study. 363–72.

Vives-Soler, A., & Chimenos-Küstner, E. (2020). Effect of probiotics as a complement to non-surgical periodontal therapy in chronic periodontitis: A systematic review. Med Oral Patol Oral y Cir Bucal. 25(2):e161–7.

Williams, R. C. (1990). Periodontal disease. The New England Journal of Medicine.

Williams, R. C., & Offenbacher, S. (2000). Periodontal medicine: the emergence of a new branch of periodontology. Periodontol. 23(7):9–12.

Published

29/10/2021

How to Cite

OLIVEIRA, A. C. do N.; SOUSA, G. de A.; SANTOS, N.; BORGES, C. D. Clinical effect of the use of probitics as an adjuvant to the non-surgical periodontal treatment of periodontitis: systematic review. Research, Society and Development, [S. l.], v. 10, n. 14, p. e149101421703, 2021. DOI: 10.33448/rsd-v10i14.21703. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21703. Acesso em: 23 nov. 2024.

Issue

Section

Review Article