Sociodemographic and clinical profile of 49 patients with oral lichen planus: a 10-year retrospective study
DOI:
https://doi.org/10.33448/rsd-v11i6.29313Keywords:
Lichen planus; Oral lichen planus; Epidemiology; Classification; Skin disease; Chronic disease.Abstract
Considering a few epidemiologic studies which describes clinic and pathologic features and prevalence of oral lichen planus (OLP) in Brazil as well as the importance of such studies in order of health care services plans and to verify changes along the years, the present study aimed to evaluate the sociodemographic and clinical profile of 49 participants diagnosed with OLP during a period of ten years. For the sample selection, the clinical and histopathological criteria for the diagnosis of OLP proposed by the American Academy of Oral and Maxillofacial Pathology were used, except for the criterion “absence of epithelial dysplasia”. Most individuals were female (75.5%; p = 0.0005). White individuals were significantly older than the black individuals (67.7 vs 49.2 years; p = 0.001). Lesions affecting multiple bilateral/symmetric sites were more common than lesions in a single bilateral/symmetric site (77.6%; p = 0.0001). The most commonly affected sites were buccal mucosa (85.7%), tongue (65.3%), gingiva (42.9%), and lips (32.7%). Most lesions were white (reticular pattern was found in 93.9% and plaque in 75.5% of cases). Plaque pattern was more common in older individuals (p = 0.006). During the different moments of evaluations some individuals did not meet the American Academy of Oral and Maxillofacial Pathology criteria due to the absence of oral lesions with multifocal symmetric distribution. Therefore, in a first consultation, if the patient does not present multifocal symmetric distributed lesions, the diagnosis of OLP cannot be excluded and the patient should be followed-up.
References
Beloqui, J. A. (2017). Alguns dados sobre a situação da Hepatite C no Brasil para ativistas de HIV/AIDS.
Boñar-Alvarez, P., Pérez Sayáns, M., Garcia-Garcia, A., Chamorro-Petronacci, C., Gándara-Vila, P., Luces-González, R., Otero Rey, E., Blanco-Carrión, A., & Suárez-Peñaranda, J. (2019). Correlation between clinical and pathological features of oral lichen planus. Medicine, 98(8). https://doi.org/10.1097/MD.0000000000014614
Cascone, M., Celentano, A., Adamo, D., Leuci, S., Ruoppo, E., & Mignogna, M. D. (2017). Oral lichen planus in childhood: A case series. International Journal of Dermatology, 56(6), 641–652. https://doi.org/10.1111/ijd.13571
Cassol-Spanemberg, J., Blanco-Carrión, A., Rodríguez-de Rivera-Campillo, M.-E., Estrugo-Devesa, A., Jané-Salas, E., & López-López, J. (2019). Cutaneous, genital and oral lichen planus: A descriptive study of 274 patients. Medicina Oral, Patologia Oral Y Cirugia Bucal, 24(1), e1–e7. https://doi.org/10.4317/medoral.22656
Cheng, Y.-S. L., Gould, A., Kurago, Z., Fantasia, J., & Muller, S. (2016). Diagnosis of oral lichen planus: A position paper of the American Academy of Oral and Maxillofacial Pathology. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 122(3), 332–354. https://doi.org/10.1016/j.oooo.2016.05.004
de Lima, S.-L.-G., de Arruda, J.-A.-A., Abreu, L.-G., Mesquita, R.-A., Ribeiro-Rotta, R.-F., Mendonça, E.-F., Arantes, D.-A.-C., & Batista, A.-C. (2019). Clinicopathologic data of individuals with oral lichen planus: A Brazilian case series. Journal of Clinical and Experimental Dentistry, 11(12), e1109–e1119. https://doi.org/10.4317/jced.56379
Diop, A., Ly, F., Ndiaye, M. T., Seck, B., El Omari, A., Diouf, A., Tajaoui, M., Diadie, S., Ahy Diatta, B., Ndiaye, M., Diallo, M., Niang, S., Kane, A., & Thierno Dieng, M. (2020). Epidemiology, clinical features, and associated factors in 78 cases of lichen planus on black skin. International Journal of Dermatology, 59(2), 137–142. https://doi.org/10.1111/ijd.14698
González-Moles, M. Á., Ruiz-Ávila, I., González-Ruiz, L., Ayén, Á., Gil-Montoya, J. A., & Ramos-García, P. (2019). Malignant transformation risk of oral lichen planus: A systematic review and comprehensive meta-analysis. Oral Oncology, 96, 121–130. https://doi.org/10.1016/j.oraloncology.2019.07.012
González‐Moles, M. Á., Warnakulasuriya, S., González‐Ruiz, I., González‐Ruiz, L., Ayén, Á., Lenouvel, D., Ruiz‐Ávila, I., & Ramos‐García, P. (2020). Worldwide prevalence of oral lichen planus: A systematic review and meta‐analysis. Oral Diseases, odi.13323. https://doi.org/10.1111/odi.13323
Gümrü, B. (2013). A retrospective study of 370 patients with oral lichen planus in Turkey. Medicina Oral, Patologia Oral Y Cirugia Bucal, 18(3), e427-432. https://doi.org/10.4317/medoral.18356
Idrees, M., Kujan, O., Shearston, K., & Farah, C. S. (2021). Oral lichen planus has a very low malignant transformation rate: A systematic review and meta-analysis using strict diagnostic and inclusion criteria. Journal of Oral Pathology & Medicine, 50(3), 287–298. https://doi.org/10.1111/jop.12996
Kaomongkolgit, R., Daroonpan, P., Tantanapornkul, W., & Palasuk, J. (2019). Clinical profile of 102 patients with oral lichen planus in Thailand. Journal of Clinical and Experimental Dentistry, 11(7), e625–e629. https://doi.org/10.4317/jced.55814
Manomaivat, T., Pongsiriwet, S., Kuansuwan, C., Thosaporn, W., Tachasuttirut, K., & Iamaroon, A. (2018). Association between hepatitis C infection in Thai patients with oral lichen planus: A case-control study. Journal of Investigative and Clinical Dentistry, 9(2), e12316. https://doi.org/10.1111/jicd.12316
McCreary, C., & Ríordáin, R. N. (2010). Systemic Diseases and the Elderly. Dental Update, 37(9), 604–607. https://doi.org/10.12968/denu.2010.37.9.604
Ministério da Saúde. (2019). Hipertensão é diagnosticada em 24,7% da população, segundo a pesquisa Vigitel. https://www.saude.gov.br/noticias/agencia-saude/45446-no-brasil-388-pessoas-morrem-por-dia-por-hipertensao
Oliveira Alves, M. G., Almeida, J. D., Balducci, I., & Guimarães Cabral, L. A. (2010). Oral lichen planus: A retrospective study of 110 Brazilian patients. BMC Research Notes, 3(1), 157. https://doi.org/10.1186/1756-0500-3-157
Parashar, P. (2011). Oral lichen planus. Otolaryngologic Clinics of North America, 44(1), 89–107, vi. https://doi.org/10.1016/j.otc.2010.09.004
Radochová, V., Dřízhal, I., & Slezák, R. (2014). A retrospective study of 171 patients with oral lichen planus in the East Bohemia—Czech Republic—Single center experience. Journal of Clinical and Experimental Dentistry, 6(5), e556-561. https://doi.org/10.4317/jced.51784
Rimkevičius, A., Aleksejūnienė, J., Pūrienė, A., Šeinin, D., & Rastenienė, R. (2017). Oral lichen planus: A 4-year clinical follow-up study. Turkish Journal of Medical Sciences, 47(2), 514–522. https://doi.org/10.3906/sag-1511-94
Shengyuan, L., Songpo, Y., Wen, W., Wenjing, T., Haitao, Z., & Binyou, W. (2009). Hepatitis C Virus and Lichen Planus: A Reciprocal Association Determined by a Meta-analysis. Archives of Dermatology, 145(9). https://doi.org/10.1001/archdermatol.2009.200
Thorn, J. J., Holmstrup, P., Rindum, J., & Pindborg, J. J. (1988). Course of various clinical forms of oral lichen planus. A prospective follow-up study of 611 patients. Journal of Oral Pathology, 17(5), 213–218. https://doi.org/10.1111/j.1600-0714.1988.tb01527.x
Torrente-Castells, E., Figueiredo, R., Berini-Aytes, L., & Gay-Escoda, C. (2010). Clinical features of oral lichen planus. A retrospective study of 65 cases. Medicina Oral Patología Oral y Cirugia Bucal, e685–e690. https://doi.org/10.4317/medoral.15.e685
Van der Meij, E. H., & Van der Waal, I. (2003). Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications. Journal of Oral Pathology & Medicine: Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 32(9), 507–512.
Warnakulasuriya, S., Kujan, O., Aguirre‐Urizar, J. M., Bagan, J. V., González‐Moles, M. Á., Kerr, A. R., Lodi, G., Mello, F. W., Monteiro, L., Ogden, G. R., Sloan, P., & Johnson, N. W. (2020). Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer. Oral Diseases, odi.13704. https://doi.org/10.1111/odi.13704
Wei, Z., Hou, Q., Xu, H., Jiang, L., & Chen, Q. (2018). Evidence of genetic factors involved in oral lichen planus pathogenesis. Oral Diseases, 24(5), 864–865. https://doi.org/10.1111/odi.12716
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Copyright (c) 2022 Letícia Côgo Marques; Laiza Angela de Medeiros Nunes da Silva; Tamiris Ramos Vargas; Licínio Esmeraldo da Silva; Karin Soares Cunha; Arley Silva Junior; Danielle Castex Conde
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