Reduction of Framingham Cardiovascular Risk in obese patients submitted to Vertical Gastrectomy (Sleeve) and Roux-en-y Gastroplasty (Bypass) in a private instituition

Authors

DOI:

https://doi.org/10.33448/rsd-v11i8.30906

Keywords:

Bariatric surgery; Comorbidity; Obesity.

Abstract

Objective: To analyze the impact of bariatric surgery on the 10-year Framingham BMI cardiovascular risk score, comparing pre- and postoperative data from those patients undergoing sleeve gastrectomy and Roux-en-Y gastroplasty. Methodology: Retrospective, observational, single-center study, performed by collecting data from 50 participants undergoing laparoscopic bariatric surgery, in a private institution, between 2019 and 2021. After exclusion criteria, 40 patients were studied. Those who met the criteria for calculating the Framingham risk score (FCR) BMI at 10 years, with analysis after 6 and 12 months, were included. Data examined by percentage frequency, Shapiro-Wilks, Mann-Whitney and Kruskal-Wallis tests. Admitted significance level was 5%. Results: The FHR reduction rate was 3.41% in females and 7.38% in males. The variation of the normality pattern of the FHR for age in the pre-surgical period was 4.9%, after 6 months and 1 year it was reduced to 1.5% and 0.7%, respectively. There was no statistical difference between the procedures. Specific treatment for comorbidities was discontinued in 80% of those with diabetes and 85.7% of those with hypertension. Conclusion: There was a significant association between bariatric surgery and reduction in FHR, regardless of the technique used.

References

Adams, T. D., Davidson, L. E., Litwin, S. E., & Hunt, S. C. (2012). Gastrointestinal Surgery: Cardiovascular Risk ReductionandImprovedLong-TermSurvival in PatientswithObesityand Diabetes. CurrentAtherosclerosisReports, 14(6), 606–615. 10.1007/s11883-012-0286-4

Ammar, W., Basset, H. A., AL Faramawy, A., Hegazy, T., &Sharaf, Y. (2020). Bariatricsurgeryand cardiovascular outcome. The Egyptian Heart Journal, 72(1), 1-10. 10.1186/s43044-020-00096-8

Aronne, L. J., Brown, W. V., &Isoldi, K. K. (2007). Cardiovascular disease in obesity: A review ofrelatedriskfactorsandrisk-reductionstrategies. JournalofClinicalLipidology, 1(6), 575–582.10.1016/j.jacl.2007.10.005

Batsis, J. A., Sarr, M. G., Collazo-Clavell, M. L., Thomas, R. J., Romero-Corral, A., Somers, V. K., & Lopez-Jimenez, F. (2008). Cardiovascular Risk AfterBariatricSurgery for Obesity. The American Journal of Cardiology, 102(7), 930–937. 10.1016/j.amjcard.2008.05.040

Benaiges, D., Goday, A., Ramon, J. M., Hernandez, E., Pera, M., & Cano, J. F. (2011). Laparoscopicsleevegastrectomyandlaparoscopicgastricbypass are equallyeffective for reductionof cardiovascular risk in severelyobesepatientsatoneyearof follow-up. Surgery for ObesityandRelatedDiseases, 7(5), 575–580. 10.1016/j.soard.2011.03.002

Castanha, C. R., TCBC-PE, Á. A. B. F., Castanha, A. R., Belo, G. de Q. M. B., Lacerda, R. M. R., & Vilar, L. (2018). Avaliação da qualidade de vida, perda de peso e comorbidades de pacientes submetidos à cirurgia bariátrica. Revista Do Colégio Brasileiro de Cirurgiões, 45(3). 10.1590/0100-6991e-20181864

Doumouras, A. G., Wong, J. A., Paterson, J. M., Lee, Y., Sivapathasundaram, B., Tarride, J.-E., Thabane, L., Hong, D., Yusuf, S., & Anvari, M. (2021). Bariatric Surgery and Cardiovascular Outcomes in Patients With Obesity and Cardiovascular Disease: Circulation, 143(15), 1468–1480. 10.1161/circulationaha.120.052386

English, W. J., Spann, M. D., Aher, C. V., & Williams, D. B. (2020). Cardiovascular risk reduction following metabolic and bariatric surgery. Annals of Translational Medicine, 8(S1), S12–S12. 10.21037/atm.2020.01.88

Gutierrez-Blanco, D., Funes-Romero, D., Madiraju, S., Perez-Quirante, F., LoMenzo, E., Szomstein, S., & Rosenthal, R. J. (2017). ReductionofFramingham BMI score afterrapidweightloss in severelyobesesubjectsundergoingsleevegastrectomy: a single institutionexperience. SurgicalEndoscopy, 32(3), 1248–1254. 10.1007/s00464-017-5799-z

Heneghan, H. M., Meron-Eldar, S., Brethauer, S. A., Schauer, P. R., & Young, J. B. (2011). EffectofBariatricSurgeryon Cardiovascular Risk Profile†Drs. HeneghanandMeron-Eldar contributedequallytothisarticle. The American Journal of Cardiology, 108(10), 1499–1507. 10.1016/j.amjcard.2011.06.076

Ilias, E. J. (2007). Consequências fisiológicas, psicológicas e metabólicas da cirurgia bariátrica. Revista Da Associação Médica Brasileira, 53(2), 98–98. 10.1590/s0104-42302007000200004

Jonker, F. H. W., van Houten, V. A. A., Wijngaarden, L. H., Klaassen, R. A., de Smet, A. A. E. A., Niezen, A., Schelfhout, L. J. D. M., Bruning, T. A., & van der Harst, E. (2017). Age-RelatedEffectsofBariatricSurgeryon Early Atherosclerosisand Cardiovascular Risk Reduction. ObesitySurgery, 28(4), 1040–1046. 10.1007/s11695-017-2962-5

Kligman, M. D., Dexter, D. J., Omer, S., & Park, A. E. (2008). Shrinking cardiovascular riskthroughbariatricsurgery: applicationofFraminghamrisk score in gastricbypass. Surgery, 143(4), 533–538. 10.1016/j.surg.2007.10.021

Levy, P., Fried, M., Santini, F., &Finer, N. (2007). The comparativeeffectsofbariatricsurgeryonweightandtype 2 diabetes. ObesitySurgery, 17(9), 1248–1256. 10.1007/s11695-007-9214-z

Lotufo, P. A. (2008). O escore de risco de Framingham para doenças cardiovasculares. Revista de Medicina, 87(4), 232-237. 10.11606/issn.1679-9836.v87i4p232-237

Milla, C., Fonseca, M., Gutierrez, D., Romero, D., LoMenzo, E., Cubeddu, R., Szomstein, S., & Rosenthal, R. J. (2020). The ImpactofEthnicityon Cardiovascular Risk Reductionand Heart Age AfterBariatricSurgery. ObesitySurgery, 30(5), 1679–1684. 10.1007/s11695-019-04341-1

Pedron, F. F., Alvarez, G. da C., Patias, L. D., Machado, A. C. de A., de Lima, L. O., de Moura, D. S., Calcing, A., & de Moraes, C. M. B. (2021). ImpactofExcessiveWeightLosson Cardiovascular Risk AfterTwo Years ofBariatricSurgery. Research Square. 10.21203/rs.3.rs-350367/v1

Ribaric, G., Buchwald, J. N., &McGlennon, T. W. (2013). Diabetes andWeight in ComparativeStudiesofBariatricSurgeryvsConventional Medical Therapy: A Systematic Review and Meta-Analysis. ObesitySurgery, 24(3), 437–455. 10.1007/s11695-013-1160-3

Ricci, C., Gaeta, M., Rausa, E., Macchitella, Y., &Bonavina, L. (2013). Early ImpactofBariatricSurgeryonType II Diabetes, Hypertension, andHyperlipidemia: A Systematic Review, Meta-Analysisand Meta-Regressionon 6,587 Patients. ObesitySurgery, 24(4), 522–528. 10.1007/s11695-013-1121-x

Sjöström, C. D., Lissner, L., Wedel, H., &Sjöström, L. (1999). Reduction in Incidenceof Diabetes, HypertensionandLipidDisturbancesafterIntentionalWeightLossInducedbyBariatricSurgery: the SOS InterventionStudy. ObesityResearch, 7(5), 477–484. 10.1002/j.1550-8528.1999.tb00436.x

Vogel, J. A., Franklin, B. A., Zalesin, K. C., Trivax, J. E., Krause, K. R., Chengelis, D. L., &McCullough, P. A. (2007). Reduction in PredictedCoronary Heart Disease Risk AfterSubstantialWeightReductionAfterBariatricSurgery. The American JournalofCardiology, 99(2), 222–226. 10.1016/j.amjcard.2006.08.017

Zeve, J. L. de M., Novais, P. O., & Júnior, N. de O. (2012). Técnicas em cirurgia bariátrica: uma revisão da literatura. Ciência & Saúde, 5(2), 132–140. 10.15448/1983-652X.2012.2.10966

Published

21/06/2022

How to Cite

MENEZES, V. C.; FORNARI, J. C. de S. .; CARDOSO, D. S. .; SANTOS, M. P. dos; SANTOS FILHO, P. V. dos. Reduction of Framingham Cardiovascular Risk in obese patients submitted to Vertical Gastrectomy (Sleeve) and Roux-en-y Gastroplasty (Bypass) in a private instituition. Research, Society and Development, [S. l.], v. 11, n. 8, p. e35911830906, 2022. DOI: 10.33448/rsd-v11i8.30906. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30906. Acesso em: 26 dec. 2024.

Issue

Section

Health Sciences