Use of Deep Brain Stimulation (DBS) for the treatment of Parkinson's disease: an integrative literature review
DOI:
https://doi.org/10.33448/rsd-v11i8.31277Keywords:
Neurosurgery; Deep brain stimulation; Parkinson's disease.Abstract
Introduction: Parkinson's Disease (PD) is the second most common neurodegenerative disease and its prevalence has increased in recent decades. Deep brain stimulation (DBS) is an established treatment for severe Parkinson's disease (PD), dystonia and tremor, and has an emerging role in a number of other neurological and neuropsychiatric conditions. However, its widespread adoption is currently limited by cost, side effects, and partial effectiveness. Objective: to explain and describe the Deep Brain Stimulation method for the control and treatment of Parkinson's Disease. Search methodology: this is a descriptive narrative review of the literature, through online access to PubMed, Scielo, CDSR, Google Scholar, BVS and EBSCO, in September 2021. Results and discussion: DBS can interact with pathological neural networks in a way that either stimulates or inhibits certain pathways in order to eliminate or subdue the unwanted circuit in the basal ganglia loops, this mechanism became known as “blocking” of the diseased network. Controlled stimulation reduces this hyperactivity and consequently removes the noise, reestablishing the transmission of neural information and consequent return control of the movement. Final considerations: the treatment consists of electrical stimulation in several regions of the brain, for years without interruption. The electrical current used is very small, made at strategic points in the brain by implanting electrodes, which are mostly deep.
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Copyright (c) 2022 Francisco Edes da Silva Pinheiro; Bárbara Ferreira de Brito; Bárbara Queiroz de Figueiredo; Camilla Ariete Vitorino Dias Soares; Carlos Antônio da Silva Júnior; Cynthia Moraes Alvim; Diândria Mendonça Martins do Prado; Luciana Fernanda Pereira Lopes; Maria Laís Sousa Alencar Pereira; Paulo da Costa Araújo
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