Analysis of the profile of Healthcare-Associated Infections in pediatric patients from a Brazilian hospital post-COVID-19 pandemic

Authors

DOI:

https://doi.org/10.33448/rsd-v13i11.47293

Keywords:

Cross infection; Pediatrics; Hospitals, pediatric; COVID-19.

Abstract

Objective: to assess the profile of healthcare-associated infections in pediatric patients from a Brazilian university hospital after the COVID-19 pandemic, aiming to identify epidemiological patterns and provide insights to improve prevention and control strategies. Methodology: this is a retrospective cross-sectional study, analyzing data from pediatric patients hospitalized between January 2022 and December 2023. Information was obtained from electronic medical records, including age, gender, comorbidities, length of stay, and the use of invasive devices. The sample consisted of patients aged 0 to 12 years, whose data were analyzed using descriptive statistics and significance tests. Results: a total of 69 patients were analyzed, 57.1% of whom were male. There were 7 co-infected patients, totaling 76 cases. The most prevalent age group was under 1 year (36.2%). Invasive devices included peripheral central insertion catheters (27.3%) and orotracheal tubes (27.3%). The median length of hospital stay was 24 days. The most common were surgical site infections (40.7%), followed by primary bloodstream infections (14.47%) and pneumonias (13.16%). The most prevalent microorganisms were Escherichia coli (15%) and Enterococcus sp. (15%). Of the positive cultures, 50% were gram-negative, and 37.5% showed resistance profiles. Conclusion: the study highlights the importance of continuous infection control practices, emphasizing the impact of invasive devices and the prevalence of multidrug-resistant pathogens in the pediatric environment.

References

Abubakar, U., Al-Anazi, M., Alanazi, Z., & Rodríguez-Baño, J. (2023). Impacto da pandemia de COVID-19 em patógenos gram-positivos e gram-negativos multirresistentes: uma revisão sistemática. Journal of Infection and Public Health , 16 (3), 320–331. https://doi.org/10.1016/j.jiph.2022.12.022

Abubakar, U., Usman, M N, Baba, M., Sulaiman, A., Kolo, M., Adamu, F., & Saleh Jaber, A A (2022). Práticas e percepção de profissionais de saúde em relação às medidas de controle de infecção durante a pandemia de COVID-19: uma pesquisa transversal online da Nigéria. Journal of Infection in Developing Countries , 16 (9), 1398–1405. https://doi.org/10.3855/jidc.14066

Advani, S D, Sickbert-Bennett, E., Moehring, R., Cromer, A., Lokhnygina, Y., Dodds-Ashley, E., Kalu, IC, DiBiase, L., Weber, D J, Anderson, D J, & C D C Prevention Epicenters Program. (2023). O impacto desproporcional da pandemia da doença do Coronavírus 2019 (COVID-19) em infecções associadas à assistência à saúde em hospitais comunitários: necessidade de expansão da força de trabalho de doenças infecciosas. Doenças Infecciosas Clínicas: Uma Publicação Oficial da Sociedade de Doenças Infecciosas da América , 76 (3), e34–e41. https://doi.org/10.1093/cid/ciac684

Alvares, P. A., Arnoni, M. V., da Silva, C. B., Sáfadi, M. A. P., & Mimica, M. J. (2019). Hospital-acquired infections in children: A Latin American tertiary teaching hospital 5-year experience. The Pediatric Infectious Disease Journal, 38(1), e12–e14. https://doi.org/10.1097/inf.0000000000002046

ANVISA (2021). Programa Nacional de Prevenção e Controle de Infecções Relacionadas à Assistência à Saúde (PNPCIRAS) 2021 a 2025. Agência Nacional de Vigilância Sanitária, Brasília, 05 mar.

Ataiyero, Y., Dyson, J., & Graham, M. (2019). Barriers to hand hygiene practices among health care workers in sub-Saharan African countries: A narrative review. American Journal of Infection Control, 47(5), 565–573. https://doi.org/10.1016/j.ajic.2018.09.014

Bloch, N., Rüfenacht, S., Ludwinek, M., Frick, W., Kleger, G.-R., Schneider, F., Albrich, W. C., Flury, D., Kuster, S. P., Schlegel, M., & Kohler, P. (2023). Healthcare associated infections in intensive care unit patients with and without COVID-19: a single center prospective surveillance study. Antimicrobial Resistance and Infection Control, 12(1), 147. https://doi.org/10.1186/s13756-023-01353-6

Brasil (2005). Pediatria: prevenção e controle de infecção hospitalar. Agência Nacional de Vigilância Sanitária.

Fletcher, G. S. (2021). Epidemiologia clínica: Elementos essenciais (6ª ed.). Editora Artmed.

Freire, I. L. S., Menezes, L. C. C. d., Sousa, N. M. L. d., Araújo, R. d. O. e., Vasconcelos, Q. L. D. d. A. Q., & Torres, G. d. V. (2013). Epidemiologia das Infecções Relacionadas à Assistência à Saúde em Unidade de Terapia Intensiva Pediátrica.

Horan, T. C., Andrus, M., & Dudeck, M. A. (2008). CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. American Journal of Infection Control, 36(5), 309–332. https://doi.org/10.1016/j.ajic.2008.03.002

Leoncio, J. M., Almeida, V. F. de, Ferrari, R. A. P., Capobiango, J. D., Kerbauy, G., & Tacla, M. T. G. M. (2019). Impacto das infecções relacionadas à assistência à saúde nos custos da hospitalização de crianças. Revista Da Escola de Enfermagem Da U S P, 53. https://doi.org/10.1590/s1980-220x2018016303486

McBride, D. L. (2021). The impact of visiting restrictions during the COVID-19 pandemic on pediatric patients. Journal of Pediatric Nursing, 61, 436–438. https://doi.org/10.1016/j.pedn.2021.09.004

Mishra, P., Pandey, C. M., Singh, U., Gupta, A., Sahu, C., & Keshri, A. (2019). Descriptive statistics and normality tests for statistical data. Annals of Cardiac Anaesthesia, 22(1), 67–72. https://doi.org/10.4103/aca.ACA_157_18

Musolino, A. M., Supino, M. C., Buonsenso, D., Ferro, V., Valentini, P., Magistrelli, A., Lombardi, M. H., Romani, L., D’Argenio, P., Campana, A., & Roman Lung Ultrasound Study Team for Pediatric COVID-19 (ROMULUS COVID Team). (2020). Lung ultrasound in children with COVID-19: Preliminary findings. Ultrasound in Medicine & Biology, 46(8), 2094–2098. https://doi.org/10.1016/j.ultrasmedbio.2020.04.026

OPAS (2021). A resistência aos antimicrobianos, acelerada pela pandemia de COVID-19. Organização Pan-Americana da Saúde.

Padoveze, M. C. (2014). Associated infections: challenges to public health in Brazil. Revista de Saúde Pública.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Santa Maria/RS. Ed. UAB/NTE/UFSM.

Rodríguez-Baño, J., Rossolini, G. M., Schultsz, C., Tacconelli, E., Murthy, S., Ohmagari, N., Holmes, A., Bachmann, T., Goossens, H., Canton, R., Roberts, A. P., Henriques-Normark, B., Clancy, C. J., Huttner, B., Fagerstedt, P., Lahiri, S., Kaushic, C., Hoffman, S. J., Warren, M., … Plant, L. (2021). Antimicrobial resistance research in a post-pandemic world: Insights on antimicrobial resistance research in the COVID-19 pandemic. Journal of Global Antimicrobial Resistance, 25, 5–7. https://doi.org/10.1016/j.jgar.2021.02.013

Silva, E. P. (2022). Identificação dos principais patógenos responsáveis por Infecções Relacionadas à Assistência à Saúde em Unidades de Terapia Intensiva Neonatal: Revisão Integrativa. Research, Society and Development.

Silva, Y. F., Tacla, M. T. G. M., Costa, D. C. Z. da, Kerbauy, G., & Mendes, P. B. S. (2021). Infecção relacionada à assistência à saúde e sepse na hospitalização em pediatria. Ciência Cuidado e Saúde, 20. https://doi.org/10.4025/ciencuidsaude.v20i0.55782

Stevens, M. P., Doll, M., Pryor, R., Godbout, E., Cooper, K., & Bearman, G. (2020). Impact of COVID-19 on traditional healthcare-associated infection prevention efforts. Infection Control and Hospital Epidemiology: The Official Journal of the Society of Hospital Epidemiologists of America, 41(8), 946–947. https://doi.org/10.1017/ice.2020.141

Subramanya, S. H., Czyż, D. M., Acharya, K. P., & Humphreys, H. (2021). The potential impact of the COVID-19 pandemic on antimicrobial resistance and antibiotic stewardship. Virusdisease, 32(2), 330–337. https://doi.org/10.1007/s13337-021-00695-2

Toassi, R. F. C., & Petry, P. C. (2021). Metodologia científica aplicada à área da saúde. (2a ed.). Editora da UFRGS.

Wang, Y., Yang, J., Qiao, F., Feng, B., Hu, F., Xi, Z.-A., Wu, W., Ni, Z.-L., Liu, L., & Yuan, Y. (2022). Compared hand hygiene compliance among healthcare providers before and after the COVID-19 pandemic: A rapid review and meta-analysis. American Journal of Infection Control, 50(5), 563–571. https://doi.org/10.1016/j.ajic.2021.11.030

WHO Director-General’s opening remarks at the media briefing on COVID-19 - 11 March 2020. (n.d.). Who.int. Retrieved October 22, 2024, from https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020

Published

09/11/2024

How to Cite

CAMPOS, T. N. de .; WESSELOVICZ, R. M. .; TONON, P. H. C. .; BAIL, L. .; ITO, C. A. S. .; ARCARO, G. .; MONTES, E. G. . Analysis of the profile of Healthcare-Associated Infections in pediatric patients from a Brazilian hospital post-COVID-19 pandemic . Research, Society and Development, [S. l.], v. 13, n. 11, p. e50131147293, 2024. DOI: 10.33448/rsd-v13i11.47293. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/47293. Acesso em: 26 nov. 2024.

Issue

Section

Health Sciences