Analgesic effect of music during laser retinal photocoagulation in diabetics: A randomized, placebo-controlled, crossover trial
DOI:
https://doi.org/10.33448/rsd-v10i6.16181Keywords:
Diabetes Mellitus; Photocoagulation; Pain management; Music; Retina.Abstract
Objective: To prospectively evaluate the analgesic effect of self-selected music for patients with diabetic retinopathy who underwent laser retinal photocoagulation (LRP). Methodology: This is a controlled, randomized, blinded, two-period crossover clinical trial. Twenty patients (40 eyes) with proliferative diabetic retinopathy who underwent LRP was enrolled. Listening to the patient's favorite music before and during the LRP was the non-pharmacological intervention. The control group (CG) was composed of patients who received only standard pharmacological treatment and the experimental group (EG) of those who received the intervention associated with standard pharmacological treatment. Pain was measured using the Numerical Verbal Scale. Differences in pain scores were tested using Aligned Rank Transformed ANOVA, Mann-Whitney U and Wilcoxon tests. The effect size of the differences was assessed using Rank Bisserial and Partial Square Effect Sizes. Results: Participants were predominantly male (60%), adults (57.4±9.1 years), with comorbidities (65%), with visual impairment ≥ 1 year (65%). Participants who heard music had lower pain scores (EG: 4.80±2.46) compared to those who did not (CG: 6.75±1.59; p=0.013). The application of self-selected music showed a large size of the analgesic effect (η²=0.189). Conclusion: Listening to the patient's favorite music, associated with standard analgesia, is effective in relieving acute LRP-related pain and should be incorporated into clinical practice for the multimodal treatment of pain in this procedure.
References
Araújo, R. B., Zazharias, L. C., Azevedo, B. M., Giusti, B. M., Pretti, R. C., Takahashi, W., et al. (2015). Metamizole versus placebo for panretinal photocoagulation pain control: A prospective double-masked randomized controlled study. Int J Retina Vitreous, 1(1), 8-12.
Cakmak, O., Cimen, S., Tarhan, H., Ekin, R. G., Akarken, I., Ulker, V., et al. (2017). Listening to music during shock wave lithotripsy decreases anxiety, pain, and dissatisfaction: A randomized controlled study. Wien Klin Wochenschr, 129(19-20), 687-691.
Carvalho, A. P. V., Silva, V., & Grande, A. J. (2013). Assessment of risk of bias in randomized controlled trials by the Cochrane Collaboration tool. Diagn Tratamento, 18(1), 38-44.
Castro, E. F. S., Okuda, E. A., Amatto, V. B., Almeida, H. G., Gracia, M., & Junior, N. K. (2014). Preemptive analgesia of nepafenac 0.1% in retinal photocoagulation. Rev Bras Oftalmol, 73(5), 269-272.
Chen, X., Seth, R. K., Rao, V. S., Huang, J. J., & Adelman, R. A. (2012). Effects of music therapy on intravitreal injections: A randomized clinical trial. J Ocul Pharmacol Ther, 28(4), 414-419.
Chiu, H. H. E., & Wu, P. C. (2011). Manual acupuncture for relieving pain associated with panretinal photocoagulation. J Altern Complement Med, 17(10), 915-921.
Chlan, L. & Halm, M. A. (2013). Does music ease pain and anxiety in the critically ill? Am J Crit Care, 22(6), 528-532.
Choi, S., Park, S., Bellan, L., Lee, H., & Chung, S. K. (2018). Crossover clinical trial of pain relief in cataract surgery. Int Ophthalmol, 38(3), 1027-1033.
Chow, S. C., Shao, J., & Wang, H. (2007). Sample size calculations in clinical research. Taylor & Francis.
Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Erlbaum.
Czarnecki, M. L., Turner, H. N., Collins, P. M., Doellman, D., Wrona, S., & Reynolds, J. (2011). Procedural pain management: A position statement with clinical practice recommendations. Pain Manag Nurs, 12(2), 95-111.
Dik, A. B. & Lohmann, P. M. (2020). A dor no contexto da urgência e emergência: Uma revisão integrativa. Research, Society and Development, 9(4), e105942898.
Dutra, H. S., & Reis, V. N. (2016). Experimental and quasi-experimental study designs: Definitions and challenges in nursing research. J Nurs UFPE, 10(6), 2230-2241.
Evans, J. R., Michelessi, M., & Virgili, G. (2014). Laser photocoagulation for proliferative diabetic retinopathy. Cochrane Database Syst Rev, 24(11), CD011234.
Fonseca, J. C., Lopes, M. J., & Ramos, A. F. (2013). People with pain and intervention needs: Systematic literature review. Rev Bras Enferm, 66(5), 771-778.
Huley, S. B., Cummings, S. R., Browner, W. S., Grady, D. G., & Newman, T. B. (2013). Designing clinical research. Lippincott Williams & Wilkins.
Inan, U. U., Polat, O., Inan, S., Yigit, S., & Baysal, Z. (2016). Comparison of pain scores between patients undergoing panretinal photocoagulation using navigated or pattern scan laser systems. Arq Bras Oftalmol, 79(1), 15-18.
Kankkunen, P., & Vaajoki, A. (2019) The effectiveness of music on postoperative pain among adults and children: The unused resource. Pain Manag, 9(4), 339-341.
Kay, M., & Wobbrock, J. (2020). ARTool: Aligned rank transform for nonparametric factorial ANOVAs.
Ko, B. W., Shim, J., Lee, B., & Cho, H.Y. (2009). Analgesic effects of tramadol during panretinal photocoagulation. Korean J Ophthalmol, 23(4), 273-276.
Kraemer, H. C. (2014). Biserial correlation. Wiley StatsRef: Statistics Reference Online.
Krishnaswamy, P., & Nair, S. (2020). Effect of music therapy on pain and anxiety levels of cancer patients: A pilot study. Indian J Palliat Care, 22(3), 307-311.
Kühlmann, A. Y. R., Rooij, A., Kroese, L. F., Dijk, M. V., Hunink, M. G. M. & Jeekel, J. (2018). Meta-analysis evaluating music interventions for anxiety and pain in surgery. Br J Surg, 105(7), 773-783.
Lee, J. H. (2016). The effects of music on pain: A meta-analysis. J Music Ther, 53(4), 430-477.
Lenth, R. (2019). Emmeans: Estimated Marginal Means, aka Least-Squares Means. R package version 1.4.2.
Li, W., Bryan, R. G., Kheterpal, A., Simeone F. J., Chang, C. Y., Torriani, M., & Huang, A. J. (2019). The effect of music on pain and subjective experience in image-guided musculoskeletal corticosteroid injections: A randomized controlled trial. Skeletal Radiol, 49(3), 435-441.
Lunde, S. J., Vuus, P., Garza-Villarreal, E. A., & Vase, L. (2019). Music-induced analgesia: How does music relieve pain? Pain, 160(5), 989-993.
Nilsson, U. (2008). The anxiety- and pain-reducing effects of music interventions: A systematic review. AORN J, 87(4), 780-807.
Pirelli, A., Level, P. S., Garetti, E., Ancora, G., Merazzi, D., Bellieni, C. V., & Lago, P. (2019). Literature review informs clinical guidelines for pain management during screening and laser photocoagulation for retinopathy of prematurity. Acta Paediatr, 108(4), 593-599.
Quigley, C., Ellard, R., Arreyedh, H. A., Droney, T., & Townley, D. (2019). Classical music for analgesia in laser panretinal photocoagulation for treatment of diabetic retinopathy. Ir Med J, 112(5), 941.
Ramezani, A., Entezari, M., Shahbazi, M. M., Semnani, Y., Nikkhah, H., & Yaseri, M. (2017). Analgesic effect of topical sodium diclofenac before retinal photocoagulation for diabetic retinopathy: A randomized double-masked placebo-controlled intraindividual crossover clinical trial. Korean J Ophthalmol, 31(2), 102-107.
Ribeiro, C. J. N., Araújo, A. C., Brito, S. B., Dantas, D. V., Nunes, M. S., Alves, J. A. B., & Ribeiro, M. C. O. (2018). Pain assessment of traumatic brain injury victims using the brazilian version of the Behavioral Pain Scale. Rev Bras Ter Intensiva, 30(1), 42-49.
Ribeiro, N. F. P., Ribeiro, C. J. N., Pinto, J. S., & Ribeiro, M. C. O. (2020). Is there evidence of efficacy of nonpharmacological interventions in the acute pain management during the laser retinal photocoagulation of patients with diabetic retinopathy?. Eur J Pain, 24(3), 665-666.
Richardson, C., & Waterman, H. (2009). Pain relief during panretinal photocoagulation for diabetic retinopathy: A national survey. Eye, 23(12), 2233-2237.
Santo, A. M. R., Auge, R. M. & Ferraz, C. A. (2016). Preemptive analgesia of metamizole versus ibuprofen in retinal laser photocoagulation. Rev Bras Oftalmol, 75(1), 14-17.
Song, M., Li, N., Zhang, X., Shang, Y., Yan, L., Chu, J., Sun, R., & Xu, R. (2018). Music for reducing the anxiety and pain of patients undergoing a biopsy: A meta analysis. J Adv Nurs, 74(5), 1016-1029.
Wadhwani, M., Bali, S., Bhartiya, S., Mahabir, M., Upadhaya, A., Dada T., et al. (2019). Long term effect of panretinal photocoagulation on retinal nerve fiber layer parameters in patients with proliferative diabetic retinopathy. Oman J Ophthalmol, 12(3), 181-185.
Wobbrock, J. O., Findlater, L., Gergle, D., & Higgins, J. J. (2011). The aligned rank transform for nonparametric factorial analyses using only ANOVA procedures. Conference on Human Factors in Computing Systems – Proceedings, 143-146.
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Copyright (c) 2021 Núbia Franca Passos Ribeiro; Caíque Jordan Nunes Ribeiro; Aline Láyra Carvalho Oliveira; Emilly Mayara Feitoza Dias; Moniery da Silva Santos; Allan Dantas dos Santos; Eduesley Santana Santos; Fábio Barreto Morais; Gustavo Barreto Melo; Maria do Carmo de Oliveira Ribeiro
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