Actividades biológicas y perfil químico de Batis maritima (Bataceae), especie con gran potencial para la bioprospeccion
DOI:
https://doi.org/10.33448/rsd-v10i16.23726Palabras clave:
Actividad antioxidante; Batis maritima; Caracterización fitoquímica; Citotoxicidad; Concentración de metales.Resumen
Los halófitos son plantas tolerantes a la sal, enriquecidas en compuestos metabólicos con varias aplicaciones industriales. Batis maritima es un halófito con presencia en zonas tropicales y subtropicales y el presente trabajo tuvo como objetivo investigar el extracto de hojas de B. maritima para enfoques de biotecnología y bioprospección. El presente estudio evaluó el perfil fitoquímico, el papel frente a la acetilcolinesterasa y las actividades protectoras de B. maritima. El cribado fitoquímico destacó la presencia de compuestos fenólicos, antracenos y saponinas. El análisis del contenido de metales reveló que el sodio (Na) es la sal más abundante (1 g/kg), seguida del Al (0,35 g/kg) y varios otros elementos en menor concentración. Además, las metodologías DPPH y TAC mostraron una actividad antioxidante significativa (IC50 5.17 ± 0.05 μg/mL y 0.45 ± 0.08 mg.AAEm, respectivamente). También se observó una actividad quelante de metales, con IC50 = 25,760 ± 0,3 μg / mL. Además, el extracto acuoso de B. maritima reveló un efecto anticolinesterasa de una manera dependiente de la dosis (IC50 = 0,0023 mg / ml). El ensayo de hemólisis no reveló ningún efecto tóxico. Por otro lado, el ensayo de citotoxicidad, utilizando células de fibroblastos murinos (NIH-3T3), mostró una disminución de la viabilidad celular.
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Derechos de autor 2021 Bruno Ricardo Scopel; Paulo Henrique Oliveira de Miranda; Ricardo Sérgio da Silva; João Victor de Oliveira Alves; Bruno Oliveira de Veras; Luciclaudio Cassimiro Amorim; Michelle Melgarejo da Rosa; Jorge Irapuan de Souza Barbosa; Maria Rita Cabral Sales de Melo; Ranilson de Souza Bezerra; Márcia Vanusa da Silva
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