Neumonía asociada a Ventilador (NAV) asistida por quitosano

Autores/as

DOI:

https://doi.org/10.33448/rsd-v11i3.26581

Palabras clave:

Ventilacion mecanica; Neumonía; Antibacteriano; Quitosano; Biopelícula.

Resumen

Introducción: La neumonía asociada a ventilador (NAV) es una de las principales causas de infecciones nosocomiales en las UCI, lo que conduce a un aumento de la estancia hospitalaria, gastos médicos, aumento de las tasas de morbimortalidad, con aumento de bacterias resistentes a los antibióticos, corrobora en la aplicación de nuevos biomateriales, con esto se estudia el quitosano debido a que tiene varias propiedades funcionales, como antimicrobiano. Metodología: La investigación realizada es una revisión sistemática mediante la consulta de bases de datos en línea para recopilar información. Las principales bases de datos de revistas utilizadas para la búsqueda activa de artículos fueron: ANVISA, OMS, PUBMED, Science Direct, SCIELO. Resultados y discusiones: La interacción microbiana dentro del biofilm contribuye a la PAVM, en este sentido existe una implicación en la terapia antimicrobiana, sin embargo la resistencia a los fármacos utilizados valida la necesidad de encontrar nuevos agentes antimicrobianos, el quitosano y sus derivados tienen versatilidad, baja costo y amplio espectro de actividad antimicrobiana contra bacterias grampositivas y gramnegativas, hongos filamentosos y levaduras. Conclusión: parece que una forma probable de combatir las infecciones bacterianas relacionadas con la ventilación mecánica es el quitosano y sus derivados, tienen actividades antimicrobianas relevantes y un gran potencial para su uso en el combate a la tenacidad de los microorganismos.

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Publicado

20/02/2022

Cómo citar

MENDES, L. A. P. P. F. .; SOUSA, A. R. de; RODRIGUES, I. V. .; SOUSA, J. da S. .; BACELAR , L. I. V. .; MACHADO, F. H. L. S. .; SILVA, A. P. da .; LOPES, D. C. .; PESSOA, D. R. .; PACHECO, N. I. . Neumonía asociada a Ventilador (NAV) asistida por quitosano. Research, Society and Development, [S. l.], v. 11, n. 3, p. e25111326581, 2022. DOI: 10.33448/rsd-v11i3.26581. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/26581. Acesso em: 26 dic. 2024.

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