Betaglucano como agente inmunomodulador en niños: Una revisión integradora

Autores/as

DOI:

https://doi.org/10.33448/rsd-v12i11.43533

Palabras clave:

Betaglucano; Inmunomodulación; Niños.

Resumen

El betaglucano es un polímero presente en la pared celular de varios compuestos. Su estructura es capaz de interactuar con las células de defensa del organismo, estimulándolas. Las propiedades inmunomoduladoras de este polímero se han estudiado durante muchos años. Objetivo: Este trabajo tuvo como objetivo establecer una asociación positiva entre el uso de Betaglucano y una mayor inmunidad en niños. Metodología: Se realizó una revisión integradora en las principales bases de datos en línea. Consideraciones finales: varios estudios han señalado al Betaglucano como un posible inmunomodulador en niños, lo cual es una realidad, de fácil acceso y bajo costo.

Citas

Bacha, U., Nasir, M., Iqbal, S., & Anjum, A. A. (2017). Nutraceutical, Anti-Inflammatory, and Immune Modulatory Effects of β-Glucan Isolated from Yeast. BioMed Research International, 2017, 1–14. https://doi.org/10.1155/2017/8972678

Bashir, K. M., & Choi, J.-S. (2017). Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future. International Journal of Molecular Sciences, 18(9), 1906. https://doi.org/10.3390/ijms18091906

Kim, H. S., Hong, J. T., Kim, Y., & Han, S.-B. (2011). Stimulatory Effect of β-glucans on Immune Cells. Immune Network, 11(4), 191. https://doi.org/10.4110/in.2011.11.4.191

Jesenak, M., Majtan, J., Rennerova, Z., Kyselovic, J., Banovcin, P., & Hrubisko, M. (2013). Immunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections. International Immunopharmacology, 15(2), 395–399. https://doi.org/10.1016/j.intimp.2012.11.020

Macchi, A., Esposito, C., Debernardi, F., Simoncini, D., Peirolo, A. & Castelnuovo, P. (2018). The role of immunomodulation therapy in preventing recurrent respiratory infections in children. ResearchGate.net. https://www.researchgate.net/publication/323079575_The_role_of_immunomodulation_therapy_ in_preventing_recurrent_respiratory_infections_in_children

Magnani, M., & Castro-Gómez, R. J. H. (2008). Beta-glucana de Saccharomyces cerevisiae: constituição, bioatividade e obtenção. Semina: Ciências Agrárias, 29(3), 631–650. https://doi.org/10.5433/1679-0359.2008v29n3p631

Mendes, K. D. S., Silveira, R. C. de C. P., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto - Enfermagem, 17(4), 758–764. https://doi.org/10.1590/s0104-07072008000400018

Rennerova, Z., Picó Sirvent, L., Carvajal Roca, E., Paśnik, J., Logar, M., Milošević, K., Majtan, J., & Jesenak, M. (2022). Beta-(1,3/1,6)-D-glucan from Pleurotus ostreatus in the prevention of recurrent respiratory tract infections: An international, multicentre, open-label, prospective study. Frontiers in Pediatrics, 10. https://doi.org/10.3389/fped.2022.999701

Pasnik, J., Ślemp, A., Cywinska-Bernas, A., Zeman, K. & Jesenak, M. (2017). Preventive effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections – open-label prospective study. Curr Pediatr Res; 21 (1), 99-104

Richter, J., Svozil, V., Král, V., Rajnohová Dobiášová, L., Stiborová, I., & Vetvicka, V. (2014). Clinical trials of yeast-derived β-(1,3) glucan in children: effects on innate immunity. Annals of Translational Medicine, 2(2), 15. https://doi.org/10.3978/j.issn.2305-5839.2014.02.01

Richter, J., Svozil, V., Král, V., Rajnohová Dobiášová, L., & Vetvicka, V. (2015). β-glucan affects mucosal immunity in children with chronic respiratory problems under physical stress: clinical trials. Annals of Translational Medicine, 3(4). https://doi.org/10.3978/j.issn.2305-5839.2015.03.20

Rop, O., Mlcek, J., & Jurikova, T. (2009). Beta-glucans in higher fungi and their health effects. Nutrition Reviews, 67(11), 624–631. https://doi.org/10.1111/j.1753-4887.2009.00230.x

Pérsio Roxo Júnior, Carvalho, B., & Fabiola Scancetti Tavares. (2009). Infecções de repetição: o que é importante para o pediatra. 27(4), 430–435. https://doi.org/10.1590/s0103-05822009000400013

Smith, P. B., Benjamin, D. K., Alexander, B. D., Johnson, M. D., Finkelman, M. A., & Steinbach, W. J. (2007). Quantification of 1,3-β- d -Glucan Levels in Children: Preliminary Data for Diagnostic Use of the β-Glucan Assay in a Pediatric Setting. Clinical and Vaccine Immunology, 14(7), 924–925. https://doi.org/10.1128/cvi.00025-07

Stier, H., Ebbeskotte, V., & Gruenwald, J. (2014). Immune-modulatory effects of dietary Yeast Beta-1,3/1,6-D-glucan. Nutrition Journal, 13(1). https://doi.org/10.1186/1475-2891-13-38

Talbott, S. M., Talbott, J. A., Talbott, T. L., & Dingler, E. (2012). β-Glucan supplementation, allergy symptoms, and quality of life in self-described ragweed allergy sufferers. Food Science & Nutrition, 1(1), 90–101. https://doi.org/10.1002/fsn3.11

Vetvicka, V., Richter, J., Svozil, V., Dobiášová, L. R., & Král, V. (2013). Placebo-driven clinical trials of yeast-derived β-(1,3) glucan in children with chronic respiratory problems. Annals of Translational Medicine, 1(3), 26–26. https://doi.org/10.3978/j.issn.2305-5839.2013.07.01

Vetvicka, V., Vannucci, L., Sima, P., & Richter, J. (2019). Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials. Molecules, 24(7). https://doi.org/10.3390/molecules24071251

Vetvicka, V., & Vetvickova, J. (2014). Anti-Stress Action of an Orally-Given Combination of Resveratrol, β-Glucan, and Vitamin C. Molecules, 19(9), 13724–13734. https://doi.org/10.3390/molecules190913724

Wichers, H. (2009). Immunomodulation by food: promising concept for mitigating allergic disease? Analytical and Bioanalytical Chemistry, 395(1), 37–45. https://doi.org/10.1007/s00216-009-2838-1

Publicado

22/10/2023

Cómo citar

OLIVEIRA, L. M. de; OLIVEIRA, G. A. de. Betaglucano como agente inmunomodulador en niños: Una revisión integradora. Research, Society and Development, [S. l.], v. 12, n. 11, p. e26121143533, 2023. DOI: 10.33448/rsd-v12i11.43533. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/43533. Acesso em: 23 dic. 2024.

Número

Sección

Ciencias de la salud