Propuesta de ajustes de intervención y ventilación para corregir la asincronía entre la activación inversa refleja y la activación inversa de bajo impulso causada por la superposición de ciclos mecánicos

Autores/as

DOI:

https://doi.org/10.33448/rsd-v13i1.44635

Palabras clave:

Unidad de Terapia Intensiva; Fisioterapia; Ventilación mecánica.

Resumen

Objetivo: Proponer una corrección ventilatoria para las diversas causas de disparo inverso (RD). Método: se trata de un estudio de observación, descriptiva y cualitativa. donde se analizaron 19 pacientes sometidos a ventilación mecánica invasiva (VMI), presentando asincronía de disparador inverso. Se utilizó la maniobra de pausa espiratoria de aproximadamente 3 segundos para clasificar los grupos de pacientes con activación refleja inversa (DRR) versus impulso bajo (DRB). En ausencia de presión muscular (Pmus), estos se clasificaron en el grupo DRR y aquellos que mostraron activación de Pmus en el grupo DRB. Resultados: Se observó que las maniobras de corrección dirigidas a reducir la tensión pulmonar, como reducir el volumen corriente total (VT), reducir la frecuencia respiratoria programada (RR) y reducir la presión positiva al final de la espiración (PEEP), fueron efectivas para la corrección de la DRR. grupo. Los procedimientos de ajuste ventilatorio con determinación del RR de soporte (10 a 12 ipm), asociados con la reducción o interrupción de la sedación/bloqueador, fueron eficientes para los pacientes del grupo DBB. Conclusión: Se observa que la determinación y clasificación de las diferentes causas de RD puede orientar procedimientos de corrección clínica además de ajustes ventilatorios adecuados para cada grupo de estas asincronías, las de RRD y DRB. Los casos de RRD (RD-reflejo involuntario) mostraron una tasa de éxito del 50% en la terapia dada, siendo necesario realizar mayores investigaciones para identificar con mayor precisión la etiología de la causa refleja, por lo que se dispone de nuevos métodos de corrección en el campo científico, al Corrección de esta disincronía refleja.

Citas

Akoumianaki, E., Lyazidi, A., Rey, N., Matamis, D., Perez-Martinez, N., Giraud, R., Mancebo, J., Brochard, L., & Richard, J. M. (2013). Mechanical ventilation-induced reverse-triggered breaths: a frequently unrecognized form of neuromechanical coupling. Chest, 143(4), 927–938. https://doi.org/10.1378/chest.12-1817

Alexopoulou, C., Kondili, E., Plataki, M., & Georgopoulos, D. (2013). Patient-ventilator synchrony and sleep quality with proportional assist and pressure support ventilation. Intensive care medicine, 39(6), 1040–1047. https://doi.org/10.1007/s00134-013-2850-y

Baedorf Kassis, E., Loring, S. H., & Talmor, D. (2018). Lung volumes and transpulmonary pressure are decreased with expiratory effort and restored with passive breathing in ARDS: a reapplication of the traditional Campbell diagram. Intensive care medicine, 44(4), 534–536. https://doi.org/10.1007/s00134-018-5105-0

Barbas, C. S., Isola, A. M., Farias, A. M., Cavalcanti, A. B., Gama, A. M., Duarte, A. C., Vianna, A., Serpa Neto, A., Bravim, B.deA., Pinheiro, B.doV., Mazza, B. F., Carvalho, C. R., Toufen Júnior, C., David, C. M., Taniguchi, C., Mazza, D. D., Dragosavac, D., Toledo, D. O., Costa, E. L., Caser, E. B., & Amado, V. M. (2014). Brazilian recommendations of mechanical ventilation 2013. Part I. Revista Brasileira de terapia intensiva, 26(2), 89–121. https://doi.org/10.5935/0103-507x.20140017

Beitler, J. R., Sands, S. A., Loring, S. H., Owens, R. L., Malhotra, A., Spragg, R. G., Matthay, M. A., Thompson, B. T., & Talmor, D. (2016). Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria. Intensive care medicine, 42(9), 1427–1436. https://doi.org/10.1007/s00134-016-4423-3

Bellani G, et al. (2013) Measurement of patient-ventilator asynchrony in patients with acute respiratory distress syndrome. Crit Care Med. 41(11):2634-2643.

Blanch, L., Villagra, A., Sales, B., Montanya, J., Lucangelo, U., Luján, M., García-Esquirol, O., Chacón, E., Estruga, A., Oliva, J. C., Hernández-Abadia, A., Albaiceta, G. M., Fernández-Mondejar, E., Fernández, R., Lopez-Aguilar, J., Villar, J., Murias, G., & Kacmarek, R. M. (2015). Asynchronies during mechanical ventilation are associated with mortality. Intensive care medicine, 41(4), 633–641. https://doi.org/10.1007/s00134-015-3692-6

Branson R. D. (2011). Patient-ventilator interaction: the last 40 years. Respiratory care, 56(1), 15–24. https://doi.org/10.4187/respcare.00937

Chanques, G., Kress, J. P., Pohlman, A., Patel, S., Poston, J., Jaber, S., & Hall, J. B. (2013). Impact of ventilator adjustment and sedation-analgesia practices on severe asynchrony in patients ventilated in assist-control mode. Critical care medicine, 41(9), 2177–2187. https://doi.org/10.1097/CCM.0b013e31828c2d7a

Chao, D. C., Scheinhorn, D. J., & Stearn-Hassenpflug, M. (1997). Patient-ventilator trigger asynchrony in prolonged mechanical ventilation. Chest, 112(6), 1592–1599. https://doi.org/10.1378/chest.112.6.1592

Colombo, D., Cammarota, G., Alemani, M., Carenzo, L., Barra, F. L., Vaschetto, R., Slutsky, A. S., Della Corte, F., & Navalesi, P. (2011). Efficacy of ventilator waveforms observation in detecting patient-ventilator asynchrony. Critical care medicine, 39(11), 2452–2457. https://doi.org/10.1097/CCM.0b013e318225753c

Conti, G., Ranieri, V. M., Costa, R., Garratt, C., Wighton, A., Spinazzola, G., Urbino, R., Mascia, L., Ferrone, G., Pohjanjousi, P., Ferreyra, G., & Antonelli, M. (2016). Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: a prospective, open-label, randomised, multicentre study. Critical care (London, England), 20(1), 206. https://doi.org/10.1186/s13054-016-1386-2

de Wit, M., Miller, K. B., Green, D. A., Ostman, H. E., Gennings, C., & Epstein, S. K. (2009). Ineffective triggering predicts increased duration of mechanical ventilation. Critical care medicine, 37(10), 2740–2745. https://doi.org/10.1097/ccm.0b013e3181a98a05

de Wit, M., Pedram, S., Best, A. M., & Epstein, S. K. (2009). Observational study of patient-ventilator asynchrony and relationship to sedation level. Journal of critical care, 24(1), 74–80. https://doi.org/10.1016/j.jcrc.2008.08.011

Drouot, X., Bridoux, A., Thille, A. W., Roche-Campo, F., Cordoba-Izquierdo, A., Katsahian, S., Brochard, L., & d'Ortho, M. P. (2014). Sleep continuity: a new metric to quantify disrupted hypnograms in non-sedated intensive care unit patients. Critical care (London, England), 18(6), 628. https://doi.org/10.1186/s13054-014-0628-4.

Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa. Editora Artes Médicas.

Gilstrap, D., & MacIntyre, N. (2013). Patient-ventilator interactions. Implications for clinical management. American journal of respiratory and critical care medicine, 188(9), 1058–1068. https://doi.org/10.1164/rccm.201212-2214CI

Gorman, E. A., O'Kane, C. M., & McAuley, D. F. (2022). Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management. Lancet (London, England), 400(10358), 1157–1170. https://doi.org/10.1016/S0140-6736(22)01439-8.

Jones HA, et al. (2016). Ventilatory asynchrony in chronic obstructive pulmonary disease: clinical implications and treatment. Drug Des Devel Ther. 10:1763-1772.

Liotti, M., Brannan, S., Egan, G., Shade, R., Madden, L., Abplanalp, B., Robillard, R., Lancaster, J., Zamarripa, F. E., Fox, P. T., & Denton, D. (2001). Brain responses associated with consciousness of breathlessness (air hunger). Proceedings of the National Academy of Sciences of the United States of America, 98(4), 2035–2040. https://doi.org/10.1073/pnas.98.4.2035

Marini, J. J., Rodriguez, R. M., & Lamb, V. (1986). The inspiratory workload of patient-initiated mechanical ventilation. The American review of respiratory disease, 134(5), 902–909. https://doi.org/10.1164/arrd.1986.134.5.902

Mellott, K. G., Grap, M. J., Munro, C. L., Sessler, C. N., Wetzel, P. A., Nilsestuen, J. O., & Ketchum, J. M. (2014). Patient ventilator asynchrony in critically ill adults: frequency and types. Heart & lung: the journal of critical care, 43(3), 231–243. https://doi.org/10.1016/j.hrtlng.2014.02.002

Murias, G., Lucangelo, U., & Blanch, L. (2016). Patient-ventilator asynchrony. Current opinion in critical care, 22(1), 53–59. https://doi.org/10.1097/MCC.0000000000000270

Murray, B., Sikora, A., Mock, J. R., Devlin, T., Keats, K., Powell, R., & Bice, T. (2022). Reverse Triggering: An Introduction to Diagnosis, Management, and Pharmacologic Implications. Frontiers in Pharmacology, 22(13),879011. https:// 10.3389/fphar.2022.879011.

Nava, S., Bruschi, C., Fracchia, C., Braschi, A., & Rubini, F. (1997). Patient-ventilator interaction and inspiratory effort during pressure support ventilation in patients with different pathologies. The European respiratory journal, 10(1), 177–183. https://doi.org/10.1183/09031936.97.10010177

Piquilloud L, et al. (2012). Efficiency of ventilator triggering: a bench study comparing pressure, flow, and NAVA triggering systems. Intensive Care Med. 38(6):930-936.

Pohlman, M. C., McCallister, K. E., Schweickert, W. D., Pohlman, A. S., Nigos, C. P., Krishnan, J. A., Charbeneau, J. T., Gehlbach, B. K., Kress, J. P., & Hall, J. B. (2008). Excessive tidal volume from breath stacking during lung-protective ventilation for acute lung injury. Critical care medicine, 36(11), 3019–3023. https://doi.org/10.1097/CCM.0b013e31818b308b

Privitera, E., Gambazza, S., Rossi, V., Santambrogio, M., Binda, F., Tarello, D., Caiffa, S., Turrin, V., Casagrande, C., Battaglini, D., Panigada, M., Fumagalli, R., Pelosi, P., & Grasselli, G. (2022). Association of ventilator-free days with respiratory physiotherapy in critically ill patients with Coronavirus Disease 2019 (COVID-19) during the first pandemic wave. A propensity score-weighted analysis. Frontiers in medicine, 9, 994900. https://doi.org/10.3389/fmed.2022.994900.

Rodriguez, A., Telias, I., Damiani, L. F., Brochard, L. (2023). Reverse Triggering during Controlled Ventilation: From Physiology to Clinical Management. American Journal Critical Care Medicine. 207(5), 533-543. https:// 10.1164/rccm.202208-1477CI.

Schmidt, M., Demoule, A., Polito, A., Porchet, R., Aboab, J., Siami, S., Morelot-Panzini, C., Similowski, T., & Sharshar, T. (2011). Dyspnea in mechanically ventilated critically ill patients. Critical care medicine, 39(9), 2059–2065. https://doi.org/10.1097/CCM.0b013e31821e8779

Sieck, G. C., Ferreira, L. F., Reid, M. B., & Mantilla, C. B. (2013). Mechanical properties of respiratory muscles. Comprehensive Physiology, 3(4), 1553–1567. https://doi.org/10.1002/cphy.c130003

Silveira, J. M. N., Gallardo, A., García-Valdés, P., Ríos, F., Rodriguez, P. O., & Damiani, L. F. (2023). Reverse triggering during mechanical ventilation: Diagnosis and clinical implications. Medicine Intensive, 20(23),00169-8. https:// 10.1016/j.medine.2023.10.009.

Subirá, C., de Haro, C., Magrans, R., Fernández, R., & Blanch, L. (2018). Minimizing Asynchronies in Mechanical Ventilation: Current and Future Trends. Respiratory Care. 63(4):464-478. https:// 10.4187/respcare.05949.

Thille, A. W., Rodriguez, P., Cabello, B., Lellouche, F., & Brochard, L. (2006). Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive care medicine, 32(10), 1515–1522. https://doi.org/10.1007/s00134-006-0301-8

Tobin M. J. (2001). Advances in mechanical ventilation. The New England journal of medicine, 344(26), 1986–1996. https://doi.org/10.1056/NEJM200106283442606

Vaschetto, R., Cammarota, G., Colombo, D., Longhini, F., Grossi, F., Giovanniello, A., Della Corte, F., & Navalesi, P. (2014). Effects of propofol on patient-ventilator synchrony and interaction during pressure support ventilation and neurally adjusted ventilatory assist. Critical care medicine, 42(1), 74–82. https://doi.org/10.1097/CCM.0b013e31829e53dc

Vasconcelos, R S., Melo, L. H., Sales, R. P., Marinho, L. S., Deulefeu, F. C., Reis, R. C., Alves-de-Almeida, M., & Holanda, M. A. (2013). Effect of an automatic triggering and cycling system on comfort and patient-ventilator synchrony during pressure support ventilation. Respiration; international review of thoracic diseases, 86(6), 497–503. https://doi.org/10.1159/000353256

Vasconcelos, R. S., Sales, R. P., Melo, L. H. P., Marinho, L. S., Bastos, V. P., Nogueira, A. D. N., Ferreira, J. C., & Holanda, M. A. (2017). Influences of Duration of Inspiratory Effort, Respiratory Mechanics, and Ventilator Type on Asynchrony With Pressure Support and Proportional Assist Ventilation. Respiratory care, 62(5), 550–557. https://doi.org/10.4187/respcare.05025

Wunsch, H., Linde-Zwirble, W. T., Angus, D. C., Hartman, M. E., Milbrandt, E. B., & Kahn, J. M. (2010). The epidemiology of mechanical ventilation use in the United States. Critical care medicine, 38(10), 1947–1953. https://doi.org/10.1097/CCM.0b013e3181ef4460

Yonis, H., Crognier, L., Conil, J. M., Serres, I., Rouget, A., Virtos, M., Cougot, P., Minville, V., Fourcade, O., & Georges, B. (2015). Patient-ventilator synchrony in Neurally Adjusted Ventilatory Assist (NAVA) and Pressure Support Ventilation (PSV): a prospective observational study. BMC anesthesiology, 15, 117. https://doi.org/10.1186/s12871-015-0091-z

Yonis, H., Gobert, F., Tapponnier, R., & Guérin, C. (2015). Reverse triggering in a patient with ARDS. Intensive care medicine, 41(9), 1711–1712. https://doi.org/10.1007/s00134-015-3702-8

Publicado

10/01/2024

Cómo citar

VIEIRA FILHO, W. de A. .; FERREIRA, M. J. S. .; NUNES, J. S.; LOPES, N. L. S. .; MACIEL, F. L. .; CONCEIÇÃO, M. V. da .; KAYBERS, T. Propuesta de ajustes de intervención y ventilación para corregir la asincronía entre la activación inversa refleja y la activación inversa de bajo impulso causada por la superposición de ciclos mecánicos. Research, Society and Development, [S. l.], v. 13, n. 1, p. e4713144635, 2024. DOI: 10.33448/rsd-v13i1.44635. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/44635. Acesso em: 30 jun. 2024.

Número

Sección

Ciencias de la salud