Caracterização de nanofibras lignocelulósicas de caule de tabaco para aplicações farmacêuticas
DOI:
https://doi.org/10.33448/rsd-v10i14.22261Palavras-chave:
Caule de tabaco; Nanofibras lignocelulósicas; Nanofibras de celulose; Técnicas de caracterização; NFC.Resumo
Nanofibras lignocelulósicas derivadas do caule do tabaco podem ter inúmeras aplicações em compósitos poliméricos, tecidos, cosméticos e produtos farmacêuticos. Assim, é importante avaliar características da biomassa como a presença de nicotina. Neste estudo, as nanofibras foram obtidas por fibrilação mecânica, enquanto o teor de celulose (0,5 e 2,0%) e os métodos de secagem foram variados. As nanofibras foram caracterizadas por cromatografia em camada delgada, 1H RMN, análise morfológica, conteúdo de α-celulose, espectroscopia de infravermelho com transformada de Fourier, difração de raios-X e análises térmicas. Os resultados demonstram a ausência de nicotina no caule do tabaco. O processo de moagem foi eficiente para produzir por liofilização, nanofibras com diâmetro médio da fibra de ~ 30 nm. As concentrações de sólidos podem influenciar o diâmetro das fibras obtidas. A estabilidade térmica aumentou e a cristalinidade diminuiu quando o tratamento alcalino foi aplicado. As técnicas de caracterização aplicadas possibilitaram a avaliação do caule do tabaco e ampliaram sua aplicação na área farmacêutica.
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