Avaliação da obesidade como fator de risco para insuficiência cardíaca: overview de revisões sistemáticas

Autores

DOI:

https://doi.org/10.33448/rsd-v11i1.24380

Palavras-chave:

Insuficiência cardíaca; Obesidade; Paradoxo da obesidade.

Resumo

A população com sobrepeso e obesidade apresentam risco aumentado de mortalidade por IC. No entanto, alguns estudos apontam para a existência de um "paradoxo da obesidade" onde poderia haver um efeito protetor sobre o risco relativo de morte por IC nessas populações com IMC elevado. Dessa forma, o presente estudo teve como objetivo investigar a obesidade como fator de risco para insuficiência cardíaca. Para isso, foi realizada uma overview das revisões sistemáticas selecionando artigos das seguintes bases de dados: "Pubmed", "Scopus" e "SciElo". A partir dessa busca inicial, foram encontrados 615 artigos, restando 59 artigos para leitura na íntegra, dos quais 22 artigos foram incluídos para extração de dados usando os critérios de inclusão predefinidos. Destes 22 estudos 73% eram metanálises e 64% dos estudos são de alta qualidade metodológica de acordo com AMSTAR-2. Sobrepeso e obesidade demonstraram uma estreita relação com o aparecimento e aumento da mortalidade por IC, até mesmo foram encontrados estudos que apontam para uma interferência gênica nessa relação. Em estudos que relatam o paradoxo da obesidade, os resultados apontam para uma proteção momentânea do risco de mortalidade.

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01/01/2022

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BEZERRA, C. O. .; PAIVA, R. M. de L. .; SILVA, T. L. da .; RIBEIRO, V. S. .; RIOS, C. C. .; SOUZA, T. T. de .; REIS, W. C. T. . Avaliação da obesidade como fator de risco para insuficiência cardíaca: overview de revisões sistemáticas. Research, Society and Development, [S. l.], v. 11, n. 1, p. e0811124380, 2022. DOI: 10.33448/rsd-v11i1.24380. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/24380. Acesso em: 23 nov. 2024.

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Artigos de Revisão