Approach to pathological outcomes in neonates infected by SARS-CoV-2: an integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v12i1.39243

Keywords:

SARS-CoV-2; COVID-19; Newborns.

Abstract

  • Objective: The aim of this study is to understand the theme of vertical transmission and the possible pathological outcomes in neonates caused by SARS-CoV-2 and to verify that the infection is associated with a greater risk of any respiratory disorder and some other neonatal morbidities, but which hardly lead to to mortality. Methodology: deals with an integrative review from March to April 2022, in the SciELO, Lilacs and PubMed databases using the terms COVID-19, newborns, SARS-CoV-2, neonates, in accordance with the classification of descriptors in Health Sciences. The inclusion criteria were: articles published in Portuguese, English and Spanish between 2020 and 2021. Results: One hundred and seventy-seven articles were found, which were submitted to inclusion criteria, leaving only eleven that worked with the proposed theme, which were analyzed individually. Conclusion: in the works it was verified that it has not yet been possible to verify the vertical and transplacental transmission of SARS-CoV-2 and the symptoms are still nonspecific, which still shows several gaps when it comes to the relationship between neonates and COVID-19. Therefore, prevention must be an essential factor and more studies must be carried out in order to provide an explanation for these various issues regarding vertical transmission and symptomatology.

References

Almeida, S. L. A. C., Chávare, J., Halfeld, J. C., Costa, J. F. S., Parizzi, J. F., Primavera, J. M., Alburquerque, K. S., Rocha, L. C. P., & Oliveira, L. F de. (2021). Manifestações clínicas do COVID-19 na população pediátrica e neonatal. Brazilian Journal of Health Review, 4 (2), 4582-4591.10.34119/bjhrv4n2-047.

Araujo, J. P., Campana, K. S. S., Bussú, K. V., Sczindrowski, M., Leal, L. B., & Zani, A. V. (2021). An overview of newborn care in the COVID - 19 context: an integrative review. Online Brazilian Journal of Nursing, 20.10.17665/1676-4285.20216454.

Bardin, L. (2020). Análise de conteúdo (70ª ed.). São Paulo.

Beozzo, G. P. N. S., Carvalho, W. B., Krebs, V. L. J., Gibelli, M. A. B. C., Zacharias, R. S. B., Rossetto, L. E. S., & Francisco, R. P. V. (2020). Neonatal manifestations in COVID-19 patients at a Brazilian tertiary center. Clinics, 75.10.6061/clinics/2020/e2407.

Bringel, R. A., Souza, J. F., Reisi, L. M. A. M. C., & Vale, M. S. (2020). COVID-19 em binômio mãe-bebê: um relato de caso do hospital universitário do Maranhão. Residência pediátrica, 10 (3), 1-3.10.25060/residpediatr-2017.v10n3-395.

Carvalho, W. B., Gibelli, M. A. C., Krebs, V. L. J., Calil, V. M. L. T., Nicolau, C. M., & Johnston, C. (2020). Neonatal SARS-CoV-2 infection. Clinics (São Paulo), 75, e1996.10.6061/clinics/2020/e1996.

Costa, T. M. S., Santos, K. V. G., Rocha, R. R. A., Oliveira, E. S., Dantas, R. A. N., & Dantas, D. V. (2021). Clinical evolution of cases of COVID-19 infection in neopediatrics: a scoping review. Revista brasileira de enfermagem, 74 (suppl 1).10.1590/0034-7167-2020-0662.

Costa, C. M., Barbosa, T. C. P., Rezende, C. A., Fonseca, L. B., Araujo, J. A., Freitas, L. C. D., & Santos, R. C. (2021). Práticas do cuidado com recém-nascido em tempos de pandemia: revisão integrativa. Research, Society and Development, 10 (2)./10.33448/rsd-v10i2.12552.

Ergon, E. Y., Akbay, S., Aytemiz, G., Çelik, E. C. A., Polat, A. Ç., Umit, Z., & Paytoncu, S. (2021). Presentación de un caso novedoso de síndrome de dificultad respiratoria aguda neonatal con infección por SARS-CoV-2: posible transmisión perinatal. Arch argent Pediatr, 119 (5), 531-535.10.5546/aap.2021.e531.

Estrela, F. M., Silva, K. K. A., Cruz, M. A., & Gomes, N, P. (2020). Gestantes no contexto da pandemia da COVID-19: reflexões e desafios. Physis: revista de saúde coletiva, 30 (02), e300215.10.1590/S0103-73312020300215.

Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., Liu, L., Shan, H., Lei, C., Hui, D. S. C., Du, B., Li, L., Zeng, G., Yuen, K., Chen, R., Tang, C., Wang, T., Chen, P., Xiang, J., Li, S., Wang, J., Liang, Z., Peng, Y., Wei, L., Liu, Y., Hu, Y., Peng, P., Wang, J., Liu, J., Chen, Z., Li, G., Zheng, Z., Qiu, S., Luo, J., Ye, C., Zhu, S., & Zhong, N. (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. The new England journal of medicine, 328, 1708-1720.10.1056/NEJMoa2002032.

Joaquim, F. L., Silva, R. M. C. R. A., Caro, M. P. G., Quintana, F. C., & Pereira, E. R. (2018). Impacto das úlceras venosas na qualidade de vida dos pacientes: revisão integrativa. Revista Brasileira de Enfermagem, 71 (4), 2021–2029.10.1590/0034-7167-2017-0516.

Linehan, L., O’Donoghue, K., Dineen, S., White, J., Higgins, J. R., & Fitzgerald, B. (2021). SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19. Placenta, 104, 261-266.10.1016/j.placenta.2021.01.012.

Marín, J. E. O., & Navarrete, J. A. P. (2021). COVID-19: transmisión vertical, enfermedad y cuidados en recién nacidos. Revista científica del instituto nacional de salud, 4 (1), 19-30.10.5377/alerta.v4i1.9916.

Mendes, K. D. S., Silveira, R. C. C. P., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto – Enfermagem, 17 (4), 758-764. 10.1590/S0104-07072008000400018.

Ministério da Saúde (MS). (2020, 12 de agosto). Atenção à Saúde do Recém-nascido no contexto da Infecção pelo novo Coronavírus (SARS-CoV-2). https://portaldeboaspraticas.iff.fiocruz.br/atencao-recem-nascido/atenc%CC%A7a%CC%83o-a-saude-do-recem-nascido-no-contexto-da-infeccao-pelo-novo-coronavirus-sars-cov-2/#:~:text=Postagens-,Aten%C3%A7%C3%A3o%20%C3%A0%20Sa%C3%BAde%20do%20Rec%C3%A9m%2Dnascido% 20no%20contexto%20da%20Infec%C3%A7%C3%A3o,(SARS%2DCoV%2D2)&text=O%20documento%20apresenta%20orienta%C3%A7%C3%B5es%20relativas,%2C%20UCINCa)%20e%20alta%20hospitalar.&text=Brasil.,Minist%C3%A9rio%20da%20Sa%C3%BAde.

Ministério da Saúde (MS). (2021). Boletim epidemiológico especial doença pelo novo coronavírus – COVID-19. https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/covid-19/2021/boletim_epidemiologico_covid_75-final-13ago_15h40.pdf.

Ramiro, N. C. M. P., Pereira, M. S., Souza, R. S., & Aver, L. A. (2020). Repercussões fetais e possíveis complicações da COVID-19 durante a gestação. Saúde Coletiva, 10 (54), 2679-2684. https:10.36489/saudecoletiva.2020v10i54p2679-2690.

Rodriguez, M. V. R., Benítez, E. M., Tirado, D. G., Ávarez, M. H., & Jiménez, D. G. (2020). Infección por SARS-CoV-2 en neonatos menores de 28 días. Serie de casos multicéntrica. Anales de pediatría, 96 (2), 149-151.10.1016/j.anpedi.2020.10.019.

Rogel, V. L., Silva, R. V., Zarco, A. C., Ruelas, I. E., Vega, A. R. S,. Flores, R. H. M., & Guillén, M. V. (2021). Perinatal COVID-19: a case report, literature review, and proposal of a national system for case record. Boletim médico del hospital infantil del méxico, 78 (1), 34-40.10.24875/BMHIM.20000230.

Sociedade brasileira de pediatria (SBP). (2020, 20 de maio). Síndrome inflamatória multissistêmica em crianças e adolescentes provavelmente associada à COVID-19: uma apresentação aguda, grave e potencialmente fatal. https://www.sbp.com.br/fileadmin/user_upload/22532d-NA_Sindr_Inflamat_Multissistemica_associada_COVID19.pdf.

Sociedade de pediatria de São Paulo (SPSP). (2020). Coronavírus e Recém-Nascido: O que se Sabe Até o Momento. https://www.spsp.org.br/PDF/SPSP-DC%20Neonatologia-Covid-vers%C3%A3o3-25.09.2020.pdf.

Socarras, J. A. A., Martin, D. E. T., Gómez, A., Saldarriaga, D., & Lamus, K. C. V. (2020). SARS-CoV2 como causa de sepsis neonatal tardía, reporte de un caso. Revista Salud uis, 52 (4), 456-460.10.18273/revsal.v52n4-2020013.

Vieira, A. F. C., Poppe, A. S., & Morette, G. A., (2020). Nove meses de pandemia pela COVID-19: o que foi feito em relação ao recém-nascido?. São Paulo. https://docs.bvsalud.org/biblioref/2021/06/1253000/nove-meses-de-pandemia-pela-covid-19-o-que-foi-feito-em-relaca_4t9AB8Y.pdf.

Zhong, N. S., Zheng, B. J., Li, Y. M., Poon, L. L. M., Xie, Z. H., Chan, K. H., Li, P. H., Tan, S. Y., Chang, Q., XIE, J. P., Kiu, X. Q., Xu, J., Li, D. X., Yuen, K. Y., Peiris, J. S. M., & Guan, Y. (2003). Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. The lancet, 362 (9393), 1341-1426. 10.1016/s0140-6736(03)14630-2.

Zhu, H., Wang, L., Fang, C., Peng, S., Zhang, L., Chang, G., Xia, S., & Zhou, W. (2020). Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational pediatrics, 9 (1), 51-60. https://doi.org/10.21037/tp.2020.02.06.

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Published

01/01/2023

How to Cite

CARVALHO, A. P.; MAGALHÃES, T. C. .; SILVA, W. de S. .; CARDOSO, B. P. V. M. .; CIACCO, C. E.; FOGARIN, G. G. .; MARINI, D. C. . Approach to pathological outcomes in neonates infected by SARS-CoV-2: an integrative review. Research, Society and Development, [S. l.], v. 12, n. 1, p. e1912139243, 2023. DOI: 10.33448/rsd-v12i1.39243. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/39243. Acesso em: 19 apr. 2024.

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Vol. 12 No. 1

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Health Sciences

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Copyright (c) 2023 Ana Paula Carvalho; Thainá Cruz Magalhães; Warley de Souza Silva; Beatriz Prado Vieira Morais Cardoso; Carlos Eduardo Ciacco; Guilherme Guerini Fogarin; Danyelle Cristine Marini

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