O Papel da crononutrição nas desordens do metabolismo: uma revisão de literatura
DOI:
https://doi.org/10.33448/rsd-v12i6.42105Palavras-chave:
Crononutrição; Cronotipos; Ciclo circadiano; Clock genes; Metabolismo; Sono.Resumo
O sistema circadiano tem papel fundamental na saúde humana, podendo influenciá-la tanto de forma positiva, quanto negativa, visto que governa os ritmos biológicos diários. Disrupções nesse sistema acabam impactando o metabolismo e provocando desordens que vão desde o ganho de peso corporal ao desenvolvimento de resistência à insulina, doenças crônicas, cardiovasculares e câncer. A crononutrição tem despontado como uma opção terapêutica interessante, pois tem como foco a relação entre padrões alimentares, ritmo circadiano e saúde metabólica. Sendo assim, o objetivo deste trabalho foi avaliar o impacto do ritmo biológico nos processos fisiológicos do corpo, bem como averiguar o potencial da crononutrição na prevenção e tratamento de indivíduos em risco. Como metodologia para desenvolvimento deste trabalho foi feita uma revisão de literatura em que foram selecionados artigos científicos publicados em periódicos internacionais de 2012 a 2023. Utilizou-se para consultas às bases de dados PubMed e MDPI. Em conclusão, as pesquisas, em geral, salientam ser possível conter os efeitos da cronodisrupção e a evolução de doenças crônicas por meio de estratégias baseadas na estimulação dos sincronizadores circadianos, bem como na supressão dos fatores que desregulam o ritmo biológico. Para tanto, diversas estratégias são propostas com foco na alimentação, sono, atividade física e exposição à luz artificial.
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