Mucolytic action of bromelain: an integrative review
DOI:
https://doi.org/10.33448/rsd-v10i13.21495Keywords:
Bromelains; Mucus; Bodily Secretions., Bromelains, Mucus, Bodily secretions.Abstract
Bromelain has anti-inflammatory, antioxidant, anti-cancer properties and also works as an aid in the digestion process and as a cardioprotective agent. The aim of the study was to analyze through the scientific literature the mucolytic action of bromelain. This is a literature review of the literature, which was used to generate the guiding question: “What scientific evidence shows the mucolytic action of bromelain?”. Seven studies included in this review, all with a quantitative approach to data (100%); concentrated mainly in the year 2017 (42.9%) and all were in the English language (100%), with origin of studies published in Austria (42.9%), the European Journal of Pharmaceutics and Biopharmaceutics concentrated more publications, corresponding to 28.6%. The studies addressed the use of bromelain associated with other substances, the effects of bromelain, such as improving permeability for drugs, and its action on the intestinal mucus, making it more permeable. The study allowed for the expansion of knowledge about bromelain or bromelain as a mucolytic agent, its nutraceutical potentials and action against some pathologies, in addition to its possible use by the pharmaceutical industry for the creation of drugs that overcome the mucolytic barrier more easily.
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Copyright (c) 2021 Eduardo Henrique Barros Ferreira; Karine Costa Melo; Chrisllayne Oliveira da Silva; Jesineide Sousa da Silva ; Laila da Silva Mota Vilanova; Francisléia Falcão França Santos Siqueira ; Solygardia Albuquerque Maciel Teixeira ; Hálmisson D’Árley Santos Siqueira; Raimundo Nonato Cardoso Miranda Junior; Hádila Giovanna Santos Siqueira Cunha; Jairina Nunes Chaves; Rodolfo Ritchelle Lima dos Santos; Camilla Lohanny Azevedo Viana; Marconny Lira da Silva; Ney Rômulo de Oliveira Paula
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