Correlation between Dialysis Malnutrition Score (DMS) and Quality of Life Based on Kidney Disease Quality of Life Short Form 36 (KDQOL-SF36) in Patients with Stage 5 Chronic Kidney Disease Undergoing Hemodialysis at the Hemodialysis Unit of RSUD Negara, Jembrana, Bali in 2025

Authors

DOI:

https://doi.org/10.33448/rsd-v14i8.49223

Keywords:

Chronic Kidney Disease (CKD), Dialysis Malnutrition Score (DMS), Hemodialysis, Kidney Disease Quality of Life (KDQOL)-SF36, Quality of Life.

Abstract

Introduction: Quality of life is one of the main expected outcomes in patients with chronic kidney disease (CKD) stage 5 undergoing hemodialysis. Objective: To determine the correlation between DMS and quality of life based on KDQOL-SF36 in patients with CKD stage 5 undergoing hemodialysis at the Hemodialysis Unit of RSUD Negara, Jembrana, Bali. Methods: The study was conducted between April 7 and April 30, 2025, at the Hemodialysis Unit of RSUD Negara, Jembrana, Bali. A total of 105 patients with CKD stage 5 undergoing hemodialysis from 2015 to April 2025 participated in the study. Nutritional status was assessed using DMS, while quality of life was measured using the KDQOL-SF36 questionnaire. Results: Spearman’s correlation test showed a statistically significant correlation between DMS and quality of life based on KDQOL-SF36 (p < 0.001), with a Spearman’s correlation coefficient (r) of -0.592, indicating a moderate negative correlation. The negative direction of the correlation suggests an inverse relationship: the higher the DMS score, the lower the KDQOL-SF36 score, and vice versa. Most participants had good nutritional status based on DMS and reported good quality of life based on KDQOL-SF36. Conclusion: There is a statistically significant correlation between Dialysis Malnutrition Score and quality of life based on KDQOL-SF36 in patients with stage 5 CKD undergoing hemodialysis at the Hemodialysis Unit of RSUD Negara, Jembrana, Bali.

References

Afsar, B., & Akman, B. (2009). Depression and nonadherence are closely related in dialysis patients. Kidney International, 76(6), 679. https://doi.org/10.1038/ki.2009.225.

Akamine, C. T. & Yamamoto, R. K. (2009). Estudo dirigido: estatística descritiva. (3ed). Editora Érica.

Alshogran, O. Y., Shatnawi, E. A., Altawalbeh, S. M., Jarab, A. S., & Farah, R. I. (2021). Predictors of poor health-related quality of life among hemodialysis patients with anemia in Jordan. Health and Quality of Life Outcomes, 19(1). https://doi.org/10.1186/s12955-021-01905-7.

Animaw, Z., Walle Ayehu, G., & Abdu, H. (2022). Prevalence of chronic kidney disease and associated factors among patients with chronic illness in Ethiopia: A systematic review and meta-analysis. SAGE Open Medicine, 10. https://doi.org/10.1177/20503121221089442.

Anita, C. (2018). Kepatuhan Pembatasan Asupan Cairan Terhadap Lama Menjalani Hemodialisa. Jurnal Seminar Nasional Dan Internasional, 1(1), 104–113.

Bekman, O. R. & Costa Neto, P. L. O. (2009). Análise estatística da decisão. (2ed). Ed. Edgar Blucher.

Carrero, J. J., Stenvinkel, P., Cuppari, L., Ikizler, T. A., Kalantar-Zadeh, K., Kaysen, G., Mitch, W. E., Price, S. R., Wanner, C., Wang, A. Y. M., Ter Wee, P., & Franch, H. A. (2013). Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM). Journal of Renal Nutrition, 23(2), 77–90. https://doi.org/10.1053/j.jrn.2013.01.001.

Cohen, D. E., Lee, A., Sibbel, S., Benner, D., Brunelli, S. M., & Tentori, F. (2019). Use of the KDQOL-36TM for assessment of health-related quality of life among dialysis patients in the United States. BMC Nephrology, 20(1). https://doi.org/10.1186/s12882-019-1295-0.

Eswarappa, M., Anish, L. S., Prabhu, P. P., Chennabasappa, G. K., Gireesh, M. S., Rajashekar, Mohammad, Y., & Gangula, R. S. (2024). Health-Related Quality of Life of Patients with Chronic Kidney Disease on Maintenance Hemodialysis and Its Determinants: A Study from a Tertiary Hospital in South India. Turkish Journal of Nephrology, 33(3), 279–288. https://doi.org/10.5152/turkjnephrol.2024.22484.

Fadare, J., Olamoyegun, M., & Gbadegesin, B. A. (2015). Medication adherence and direct treatment cost among diabetes patients attending a tertiary healthcare facility in Ogbomosho, Nigeria. Malawi Medical Journal, 27(2), 65–70. https://doi.org/10.4314/mmj.v27i2.7.

Groer, M. (2001). Advanced pathophysiology. Application to clinical practice. Lippincott Williams & Wilkins Publisher. ISBN: 978-0781723367.

Harvinder, G. S., Swee, W. C. S., Karupaiah, T., Sahathevan, S., Chinna, K., Ahmad, G., Bavanandan, S., & Goh, B. L. (2016). Dialysis malnutrition and malnutrition inflammation scores: Screening tools for prediction of dialysis - related protein-energy wasting in Malaysia. Asia Pacific Journal of Clinical Nutrition, 25(1), 26–33. https://doi.org/10.6133/apjcn.2016.25.1.01.

Hayati, D. M., Widiany, F. L., & Nofiartika, F. (2021). Status gizi berdasarkan dialysis malnutrition score (DMS) dengan kualitas hidup pasien hemodialisis. Jurnal Gizi Klinik Indonesia, 18(1), 28. https://doi.org/10.22146/ijcn.60778.

Hays, R. D., Kallich, J. D., Mapes, D. L., Coons, S. J., & Carter, W. B. (1994). Development of the Kidney Disease Quality of Life (KDQOLTM) Instrument. Quality of Life Research, 3(5), 329–338. https://doi.org/10.1007/BF00451725.

Indonesian Renal Registry. (2020). Indonesian Renal Registry Annual Report 2020. Pernefri.

Joshi, V. D., Mooppil, N., & Lim, J. F. Y. (2010). Validation of the kidney disease quality of life-short form: A cross-sectional study of a dialysis-targeted health measure in singapore. BMC Nephrology, 11(1). https://doi.org/10.1186/1471-2369-11-36.

Kalantar-Zadeh, K., Kopple, J. D., Block, G., & Humphreys, M. H. (2001). A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. American Journal of Kidney Diseases, 38(6), 1251–1263. https://doi.org/10.1053/ajkd.2001.29222.

Kang, G. W., Lee, I. H., Ahn, K. S., Lee, J., Ji, Y., & Woo, J. (2015). Clinical and psychosocial factors predicting health-related quality of life in hemodialysis patients. Hemodialysis International, 19(3), 439–446. https://doi.org/10.1111/hdi.12271.

Mapes, D. L., Lopes, A. A., Satayathum, S., McCullough, K. P., Goodkin, D. A., Locatelli, F., Fukuhara, S., Young, E. W., Kurokawa, K., Saito, A., Bommer, J., Wolfe, R. A., Held, P. J., & Port, F. K. (2003). Health-related quality of life as a predictor of mortality and hospitalization: The dialysis outcomes and practice patterns study (DOPPS). Kidney International, 64(1), 339–349. https://doi.org/10.1046/j.1523-1755.2003.00072.x.

Mehrotra, R. (2015). KDOQI Clinical Practice Guideline for Hemodialysis. National Kidney Foundation.

Menteri Kesehatan Republik Indonesia. (2023). Keputusan Menteri Kesehatan Republik Indonesia Nomor Hk.01.07/Menkes/1634/2023 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana Penyakit Ginjal Kronik. Keputusan Menteri Kesehatan Republik Indonesia, 11, 1–189. https://www.kemkes.go.id/id/pnpk-2023---tata-laksana-penyakit-ginjal-kronik.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Ed.UAB/NTE/UFSM.

Pradipta, P. N., Suwitra, K., & Widiana, R. (2018). Status Nutrisi Pasien Penyakit Ginjal Kronik Yang Menjalani Hemodialisis Reguler Lebih Dari 5 Tahun Di Rumah Sakit Umum Pusat Sanglah Denpasar. Medicina, 49(2). https://doi.org/10.15562/medicina.v49i2.228.

Puspitasari, M., Afiatin, Oktaria, V., Wardhani, Y., & Wijaya, W. (2024). Five-year survival analysis and predictors of mortality of adult hemodialysis patients in Indonesia: a nationwide database analysis. International Urology and Nephrology, 56(11), 3657–3664. https://doi.org/10.1007/s11255-024-04118-1.

Shitsuka et al. (2014). Matemática fundamental para a tecnologia. São Paulo: Ed. Érica.

Stevens, P. E., Ahmed, S. B., Carrero, J. J., Foster, B., Francis, A., Hall, R. K., Herrington, W. G., Hill, G., Inker, L. A., Kazancıoğlu, R., Lamb, E., Lin, P., Madero, M., McIntyre, N., Morrow, K., Roberts, G., Sabanayagam, D., Schaeffner, E., Shlipak, M., … Levin, A. (2024). KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney International, 105(4), S117–S314. https://doi.org/10.1016/j.kint.2023.10.018.

Suwitra, K. (2014). Penyakit Ginjal Kronik. In S. Setiati, I. Alwi, A. W. Sudoyo, M. Simandibrata, B. Setyohadi, & A. F. Syam (Eds.), Buku Ajar Ilmu Penyakit Dalam Edisi Keenam (2nd ed., Vol. 1, Issue November, pp. 2159–2160).

Tabibi, H., Ashabi, A., Nozari, B., Mahdavi-Mazdeh, M., Hedayati, M., & Abdollahi, M. (2011). Comparison of various methods for determination of protein-energy malnutrition with subjective global assesment in hemodialysis patient. Iranian J Nutr Sci Food Technol, 5(4), 13–22.

Weinstein, J. R., & Anderson, S. (2010). The Aging Kidney: Physiological Changes. Advances in Chronic Kidney Disease, 17(4), 302–307. https://doi.org/10.1053/j.ackd.2010.05.002.

Widiana, I. G. R., Kandarini, Y., Bandiara, R., Indrasari, A., & Erawan, I. G. N. A. T. (2021). Penyakit Ginjal Kronik. In Gangguan Ginjal, Elektrolit, dan Keseimbangan Asam Basa (pp. 201–209). Penerbit Buku Kedokteran EGC.

Ye, W., Wang, L., Wang, Y., Wang, C., & Zeng, J. (2022). Depression and anxiety symptoms among patients receiving maintenance hemodialysis: a single center cross-sectional study. BMC Nephrology, 23(1). https://doi.org/10.1186/s12882-022-03051-8.

Downloads

Published

2025-08-10

Issue

Section

Health Sciences

How to Cite

Correlation between Dialysis Malnutrition Score (DMS) and Quality of Life Based on Kidney Disease Quality of Life Short Form 36 (KDQOL-SF36) in Patients with Stage 5 Chronic Kidney Disease Undergoing Hemodialysis at the Hemodialysis Unit of RSUD Negara, Jembrana, Bali in 2025. Research, Society and Development, [S. l.], v. 14, n. 8, p. e2514849223, 2025. DOI: 10.33448/rsd-v14i8.49223. Disponível em: https://rsdjournal.org/rsd/article/view/49223. Acesso em: 6 dec. 2025.