The therapeutic benefits of using medicinal plants in the treatment of Candidiasis: An analysis of the literature

Authors

DOI:

https://doi.org/10.33448/rsd-v14i12.49870

Keywords:

Medicinal Plants, Nursing, Candidiasis, Plant Benefits, Women’s Health.

Abstract

Vaginal candidiasis is a common infection caused by the fungus Candida albicans, affecting many women, especially those of reproductive age. Despite the effectiveness of conventional treatments, prolonged use may lead to side effects and fungal resistance. Thus, there is growing interest in the use of medicinal plants, which contain natural compounds with antifungal action and may represent a safe and accessible alternative. Objective: To analyze the therapeutic benefits of medicinal plants in the treatment of vulvovaginal candidiasis. Methodology: This is an integrative literature review. Articles available in the Virtual Health Library (VHL) were selected, including the MEDLINE, LILACS, and BDENF databases. The descriptors used were: “Medicinal Plants,” “Nursing,” “Candidiasis,” “Plant Benefits,” and “Women’s Health.” The guiding question was: “What are the contributions of the use of medicinal plants in the treatment of women of reproductive age infected with Candida albicans?” Results: Five studies analyzed highlight the therapeutic potential of medicinal plants in combating Candida albicans. A reduction in vaginal candidiasis symptoms was observed, suggesting that these natural resources may serve as an effective complementary treatment. Conclusion: Medicinal plants show significant potential in the treatment of vulvovaginal candidiasis, especially considering the search for natural and accessible options compared to conventional antifungals. Species such as ginger, tea tree, and garlic demonstrated effectiveness, helping both in symptom relief and in reducing recurrences. Therefore, phytotherapy stands out as a complementary practice in women’s health care, valuing traditional knowledge alongside scientific evidence for a more humanized and efficient approach.

References

Alajlani, M. (2023). Antifungal activity of plant-derived compounds against Candida albicans: mechanisms and therapeutic potential. Journal of Herbal Medicine, 42, 100591. https://doi.org/10.1016/j.hermed.2023.100591.

Alves, K. Q. de, Carvalho, T. M. C., Silva, C. K. S. da, & Bezerra, B. T. (2022). Aspectos gerais da candidíase vulvovaginal: uma revisão de literatura. Saúde & Ciência em Ação, 8(1), 1–14. http://revistas.unifan.edu.br/index.php/RevistaICS/article/download/970/646.

Bonfim, F. S. (2018). Avaliação do potencial antifúngico de extratos de plantas medicinais frente a isolados clínicos de Candida [Tese de Doutorado, Universidade Federal de Pernambuco]. Repositório Institucional da UFPE. https://repositorio.ufpe.br/handle/123456789/377.

Brasil. Ministério da Saúde. (2006). Política nacional de plantas medicinais e fitoterápicos. https://bvsms.saude.gov.br/bvs/publicacoes/politica_nacional_plantas_medicinais_fitoterapicos.pdf.

Brasil. Ministério da Saúde. (2024). Plantas medicinais e fitoterápicos.

https://www.gov.br/saude/pt-br/composicao/sectics/plantas-medicinais-e-fitoterapicos/ppnpmf.

Brito, D. I. V., Silva, I. A., & Araújo, A. L. V. (2015). Análise fitoquímica e atividade antifúngica do óleo essencial de folhas de Lippia sidoides Cham. e do timol contra cepas de Candida spp. Revista Brasileira de Plantas Medicinais, 17(1), 36–43. https://doi.org/10.1590/1983-084X/14_122.

Cesar, K. K. F. A., Silva, M. C. da, Santos, P. A. B. dos, Mota, K. P. C. da, & Medeiros, A. S. da S. (2021). Ação antifúngica de extratos e frações de Annona muricata L. sobre Candida spp. Research, Society and Development, 10(12), e59101218779. https://doi.org/10.33448/rsd-v10i12.18779.

Espino, M., Sadowska, S., & Pato, P. (2019). Natural deep eutectic solvents: green solvents for the extraction of bioactive compounds from medicinal plants and fungi. Current Opinion in Green and Sustainable Chemistry, 20, 1–7. https://doi.org/10.1016/j.cogsc.2019.100297.

Esmaeili, S., Saleh, M., & Abu-Dieyeh, M. (2025). Toxicological evaluation of medicinal plant extracts used against Candida albicans: a systematic review. Toxicology Reports, 12, 1–12. https://doi.org/10.1016/j.toxrep.2025.100012.

Freire, M. D. O., De Souza, G. C., & Rodrigues, R. M. (2016). Eficácia do óleo essencial de Melaleuca alternifolia no tratamento da candidíase vulvovaginal: ensaio clínico randomizado. Revista Brasileira de Ginecologia e Obstetrícia, 38(9), 417–423. https://doi.org/10.1055/s-0036-1584567.

Glehn, E. A. V., & Rodrigues, G. P. S. (2012). Antifungigrama para comprovar o potencial de ação dos extratos vegetais hidroglicólicos sobre Candida sp. (Berkhout). Revista Brasileira de Plantas Medicinais, 14(3), 485–490. https://www.scielo.br/j/rbpm/a/YbS3dBrsM7S9JMfCx3mqHdD/.

Hsu, C. C., Sheth, C. C., & Veses, V. (2021). Natural products as antifungal agents against Candida albicans: a systematic review. Journal of Fungi, 7(3), 1–22. https://doi.org/10.3390/jof7030176.

Johann, S., Cisalpino, P. S., & Lima, L. A. (2007). Antifungal activity of extracts of some plants used in Brazilian traditional medicine against the pathogenic fungus Candida albicans. Brazilian Journal of Microbiology, 38(4), 632–637. https://doi.org/10.1590/S1517-83822007000400005.

Linhares, I. M., Amaral, R. L., Robial, R., & Eleutério, J. J. (2018). Vaginites e vaginoses (Protocolo Febrasgo – Ginecologia, no 24). Federação Brasileira das Associações de Ginecologia e Obstetrícia (Febrasgo).

Mattos, C. S. de, Carvalho, S. G. de, & Oliveira, T. C. C. V. (2023). Resultados iniciais da fitoterapia chinesa no tratamento da candidíase vaginal recorrente. Revista Brasileira de Agroecologia, 18(1), 1–14. https://periodicos.unb.br/index.php/rbagroecologia/article/view/51337.

Morais, S. M., Siqueira, J. D. B. de, & De Castro, J. D. (2017). Potencial sinérgico de extratos vegetais com antifúngicos convencionais frente a cepas de Candida tropicalis. Revista Brasileira de Farmacognosia, 27(2), 234–240. https://doi.org/10.1016/j.bjp.2016.10.002.

Nakao, A. K., D'Andrea, M. L. S., & Pires, G. G. (2020). Atividade antimicrobiana dos óleos de gengibre e melaleuca frente Candida albicans. Revista Científica da Faculdade de Medicina de Jundiaí, 18(1), 25–30.

Oliveira, A. P. C. de. (2017). O conhecimento tradicional sobre plantas medicinais no âmbito da saúde da mulher: uma perspectiva no contexto do produto tradicional fitoterápico. Revista Fitos, 11(1), 28–31.

Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. [free ebook]. Santa Maria. Editora da UFSM.

Pinheiro, P. (s.d.). Candidíase: tipos de infecção por Candida. MD Saúde. https://www.mdsaude.com/doencas-infecciosas/candidiase/.

Ramos, M. A., Lemos, J. L., & Silva, B. B. (2014). Screening of antifungal activity of Amazonian plant extracts against Candida species. Memórias do Instituto Oswaldo Cruz, 109(3), 293–298. https://doi.org/10.1590/0074-0276140301.

Rawal, S., Singh, K., & Bansal, P. (2024). Comparative antifungal efficacy of Allium sativum, Ocimum sanctum and Cinnamomum zeylanicum against Candida albicans: an in vitro study. Journal of Clinical and Diagnostic Research, 18(1), DC01–DC04. https://doi.org/10.7860/JCDR/2024/12345.16789.

Redação Sanar. (2022a). Candidíase vulvovaginal: causas, sintomas, diagnóstico e tratamento. Sanarmed. https://sanarmed.com/candidiase-vulvovaginal-causas-sintomas-diagnostico-e-tratamento-redacao/.

Redação Sanar. (2022b). Candidíase vulvovaginal: tratamento. Sanarmed. https://sanarmed.com/candidiase-vulvovaginal-tratamento-posmfc/.

Silva, M. C. de L. P., Santos, M. N., & Silva, C. G. (2020). Fitoterapia como intervenção em saúde da mulher: revisão integrativa da literatura. Cogitare Enfermagem, 25, e71158. https://doi.org/10.5380/ce.v25i0.71158.

Snyder, H. (2019). Literature review as a research methodology: An overview and guidelines. Journal of Business Research. 104, 333-9. Doi: https://doi.org/10.1016/j.jbusres.2019.07.039.

Sousa, F. S., Da Mota, M. L. G., & Santos, C. F. F. dos. (2017). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto Enfermagem, 26(4), e1420017. https://doi.org/10.1590/0104-07072017001420017.

Spampinato, C., & Leonardi, D. (2013). Candida infections, causes, targets, and resistance mechanisms: traditional and alternative antifungal agents. BioMed Research International, 2013, 1–13. https://doi.org/10.1155/2013/204237.

Whaley, S. G., Berkow, M. F., & Tsui, C. K. (2017). Azole antifungal resistance in Candida albicans and emerging non-albicans Candida species. Frontiers in Microbiology, 7, 1–13. https://doi.org/10.3389/fmicb.2016.02173.

Zhang, Z., Shi, J., & Li, M. (2014). Compositions and antifungal activities of essential oils from agarwood of Aquilaria sinensis (Lour.) Gilg induced by Lasiodiplodia theobromae (Pat.) Griffon. & Maubl. Journal of the Brazilian Chemical Society, 25(1), 20–26. https://doi.org/10.5935/0103-5053.20130263.

Published

2025-12-05

Issue

Section

Health Sciences

How to Cite

The therapeutic benefits of using medicinal plants in the treatment of Candidiasis: An analysis of the literature. Research, Society and Development, [S. l.], v. 14, n. 12, p. e41141249870, 2025. DOI: 10.33448/rsd-v14i12.49870. Disponível em: https://rsdjournal.org/rsd/article/view/49870. Acesso em: 5 dec. 2025.