Rosacea: Therapeutic update and clinical approaches in dermatological practice
DOI:
https://doi.org/10.33448/rsd-v15i1.50596Keywords:
Rosacea, Inflammation, Skin Diseases, Therapeutics, Quality of Life.Abstract
Objective: To analyze the clinical, pathophysiological, and therapeutic aspects of rosacea, with emphasis on contemporary management strategies in dermatological practice. Methodology: A narrative review of the literature was conducted through systematic searches in the PubMed, SciELO, and MEDLINE databases, including studies published between 2013 and 2024 in Portuguese and English, addressing epidemiological, pathophysiological, clinical, and therapeutic aspects of rosacea. Results: The analyzed studies demonstrate that rosacea has a complex multifactorial pathophysiology, involving vascular and neurovascular dysfunction, chronic inflammation mediated by innate immunity, alterations of the cutaneous microbiome, and the influence of environmental and behavioral factors. Current evidence supports that the most effective management relies on combined and individualized therapeutic approaches, tailored to the predominant clinical phenotype and disease severity, integrating topical and systemic therapies, adjunctive procedures, and patient education. Conclusion: An integrated understanding of the clinical and pathophysiological mechanisms of rosacea supports more effective and personalized therapeutic strategies, enabling optimization of disease control, reduction of complications, and sustained improvement in patients’ quality of life.
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