COVID-19 pandemic and HIV treatment continuity: Factors associated with treatment abandonment in Maputo province, Mozambique

Authors

DOI:

https://doi.org/10.33448/rsd-v15i3.50811

Keywords:

HIV/AIDS, Antiretroviral therapy, Treatment abandonment, COVID-19, Mozambique.

Abstract

Infection with HIV/AIDS remains a major public health challenge, particularly in sub-Saharan Africa. In Mozambique, the high prevalence of the disease requires effective strategies to ensure continuity of antiretroviral therapy. However, the COVID-19 pandemic caused significant disruptions to health systems, affecting access to services and contributing to treatment interruption among many patients. This study aimed to analyse the factors associated with HIV treatment abandonment during the pandemic in Maputo Province and discuss its implications for public health. The methodology consisted of a narrative review of scientific and documentary literature, including national and international reports and scientific articles published over the last ten years. Evidence related to adherence to antiretroviral therapy, determinants of treatment abandonment, and the impact of the pandemic on HIV services was analysed. The results indicate that treatment interruption was associated with multiple factors, including fear of infection in health facilities, mobility restrictions, transportation difficulties, loss of income, and food insecurity. Additionally, structural limitations within the health system, such as long waiting times and reduced community support activities, contributed to treatment discontinuation. The study concludes that the COVID-19 pandemic significantly affected the continuity of HIV treatment in Maputo Province, highlighting the need to strengthen retention strategies and ensure continuity of essential health services during public health emergencies.

References

Audet, C. M., et al. (2017). Traditional healer treatment of HIV persists in the era of ART in Mozambique. AIDS. BMC Complement Altern Med. 17(1), 434.

doi: 10.1186/s12906-017-1934-6.

Cohen, M. S., Chen, Y. Q., McCauley, M. et al. (2016). Antiretroviral therapy for the prevention of HIV-1 transmission. New England Journal of Medicine, 375, 830–9.

Djedje, L. M. (2021). Análise dos factores culturais que influenciam o abandono ao tratamento antiretroviral entre pacientes jovens que vivem com a infecção do HIV na cidade da Matola. Monografia de Licenciatura. Repositorio da UEM

Fernandes, J. M. B., Vieira, L. T. & Castelhano, M. V. C. (2023). Revisão narrativa enquanto metodologia científica significativa: reflexões técnico-formativas. REDES – Revista Educacional da Sucesso. 3(1), 1-7. ISSN: 2763-6704.

Fumo, H. F., Banze, A. R., Baltazar, C. S., et al. (2025). COVID-19 crisis exacerbates HIV vulnerability in key populations: A formative assessment in Mozambique. BMC Health Services Research. 25(79). https://link.springer.com/article/10.1186/s12913-025-12804-8.

Gonçalves, P., Mascarenhas, P., Marcelino, R., Mabunda, N., Kroidl, A., Buck, W. C., Jani, I., Palladino, C. & Taveira, N. (2024). HIV-1 Antiretroviral Drug Resistance in Mozambique: A Systematic Review and Meta-Analysis. Viruses, 16(12), 1808. https://doi.org/10.3390/v16121808

Greenhalgh, T. (2019). How to read a paper: The basics of evidence-based medicine. BMJ Books.

Jewell, B. L., Mudimu, E., Stover, J., et al. (2020). Potential effects of disruption to HIV programmes in sub-Saharan Africa caused by COVID-19. The Lancet HIV, 7(9), e629–e640.

Joaquim, L., Miranda, M. N. S., Pimentel, V., Martins, M. D. R. O., Nhampossa, T., Abecasis, A. & Pingarilho, M. (2023). Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique. Viruses. 15(10), 1978. doi: 10.3390/v15101978. PMID: 37896757; PMCID: PMC10610786.

Jobanputra, K., et al. (2016). Factors associated with ART retention in Mozambique. Journal of the International AIDS Society.

Ministério da Saúde de Moçambique. (2022). Relatório anual dos programas de HIV/SIDA. https://pt.scribd.com/document/788316542/Relatorio-Anual-HIV-2022-FINAL.

Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. [free ebook]. Santa Maria: Editora da UFSM.

Risemberg, R. I. C. et al. (2026). A importância da metodologia científica no desenvolvimento de artigos científicos. E-Acadêmica, 7(1), e0171675. https://eacademica.org/eacademica/article/view/675.

Rother, E. T. (2007). Revisão sistemática vs. revisão narrativa. Acta Paulista de Enfermagem. 20(2), 5-6.

Uetela, D. M., et al. (2023). Impact of differentiated service delivery models on retention in HIV treatment in Mozambique. The Lancet HIV. 10(10), e674-e683. doi: 10.1016/S2352-3018(23)00184-4.

UNAIDS. (2023). Global AIDS Update 2023. https://thepath.unaids.org/.

WHO. (2021). Maintaining essential health services during the COVID-19 pandemic.

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/related-health-issues.

Published

2026-03-26

Issue

Section

Health Sciences

How to Cite

COVID-19 pandemic and HIV treatment continuity: Factors associated with treatment abandonment in Maputo province, Mozambique. Research, Society and Development, [S. l.], v. 15, n. 3, p. e7215350811, 2026. DOI: 10.33448/rsd-v15i3.50811. Disponível em: https://rsdjournal.org/rsd/article/view/50811. Acesso em: 2 apr. 2026.