Descemet's membrane rupture associated with forceps delivery: A narrative review on diagnosis and management

Authors

DOI:

https://doi.org/10.33448/rsd-v14i11.50127

Keywords:

Forceps Delivery, Amblyopia, Ophtalmology.

Abstract

Neonatal corneal opacity (NCO) is an ophthalmologic emergency that severely threatens visual development. Among its causes, obstetric trauma, particularly from forceps delivery, remains a significant, though decreasing, etiology. This trauma can cause a rupture in Descemet's membrane (DM), leading to acute corneal edema, high astigmatism, and a profound risk of irreversible amblyopia. This narrative review aims to synthesize the most recent scientific evidence (2020-2024) on the approach to NCO, focusing on the clinical, imaging, and management findings that differentiate traumatic DM ruptures from their main clinical mimics. Methods: A narrative review was conducted, searching PubMed, SciELO, and LILACS for publications from 2020 to 2024 using relevant descriptors. Results: The synthesized literature indicates that any unilateral corneal clouding in a newborn with a history of instrumented delivery mandates urgent investigation. The classic differential diagnosis is primary congenital glaucoma (PCG). Clinical examination reveals that forceps-induced tears are typically vertical or oblique, whereas Haab's striae (from PCG) are horizontal or circumferential. Tools like Anterior Segment Optical Coherence Tomography (AS-OCT) are essential for confirming the presence, location, and extent of the DM tear or detachment. Management is time-sensitive and ranges from conservative (topical hypertonics) to surgical (descemetopexy with air/gas) or, in refractory cases, keratoplasty (PKP or DSAEK). Conclusion: The approach to neonatal corneal opacity requires rapid etiological clarification. The ophthalmologist plays a central role in using clinical history and advanced imaging (AS-OCT) to distinguish traumatic from congenital causes, a distinction that dictates immediate management and the critical, long-term strategy for amblyopia prevention.

References

Altay, Y., et al. (2022). Causes of congenital corneal opacities and their management in a tertiary care center. Arquivos Brasileiros de Oftalmologia, 85(3), 269-275.

Angmo, D., et al. (2021). Management strategies and outcomes of traumatic Descemet membrane detachment in children. Indian Journal of Ophthalmology, 69(4), 882-887.

Bhandari, R., et al. (2023). Neonatal corneal opacity: A case series and review of the literature. Nepal Journal of Ophthalmology, 15(1), 123-130.

Gimenez-Aleixandre, M., et al. (2020). Management of Descemet membrane detachment secondary to forceps assisted delivery in a newborn. Archivos de la Sociedad Española de Oftalmología, 95(10), 508-511.

Gupta, N., et al. (2024). Clinical and diagnostic imaging profile of three anterior segment dysgenesis disorders presenting with infantile corneal opacities. Indian Journal of Ophthalmology, 72(1), 114-120.

Han, J., et al. (2021). Clinical outcomes of penetrating keratoplasty in children with forceps birth injury-related corneal opacity. Journal of International Medical Research, 49(11), 3000605211057549.

Harnet, T., et al. (2022). Operative vaginal delivery and neonatal ocular trauma: a retrospective cohort study. American Journal of Obstetrics and Gynecology MFM, 4(4), 100619.

Iqbal, U., et al. (2024). Comparison of Visual Outcome of Successful Descemet Membrane Endothelial Keratoplasty and Penetrating Keratoplasty. Journal of the College of Physicians and Surgeons Pakistan, 34(3), 324-328.

Kaur, K., et al. (2024). Primary Congenital Glaucoma. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

Lyu, C., et al. (2024). Outcomes of descemet stripping automated endothelial keratoplasty for pediatric descemet membrane detachment with diffuse corneal edema. Frontiers in Medicine, 11, 12436448.

Mishra, C., et al. (2024). Comparative analysis of pachymetry and assessment of corneal topography in pediatric congenital corneal opacities: A study of AS-OCT and UBM imaging modalities. Indian Journal of Ophthalmology, 72(10), 1-6.

Nakamura, R., et al. (2022). Handheld anterior segment optical coherence tomography findings in forceps injury-associated Descemet membrane rupture. Journal of American Association for Pediatric Ophthalmology and Strabismus, 26(4), 211-213.

Palioura, S., et al. (2021). Obstetric trauma-induced Descemet membrane tears: clinical features and management. Cornea, 40(1), 7-12.

Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria: Editora da UFSM.

Prasad, S., & Kumar, K. (2023). A review of congenital and neonatal corneal opacities: Diagnosis and management. Cureus, 15(8), e43245.

Romero-Rangel, I., et al. (2022). Descemet membrane detachment in a newborn after forceps delivery: A case report and literature review. Archivos de la Sociedad Española de Oftalmología (English Edition), 97(5), 282-285.

Rother, E. T. (2007). Revisão sistemática x revisão integrativa. Acta Paulista de Enfermagem, 20(2), 5-6.

Satija, E., & Tandon, R. (2024). Management of Pediatric Corneal Opacities. Seminars in Ophthalmology, 39(1), 94-103.

Shaik, J., et al. (2022). Clinical presentation and management outcomes of forceps-induced Descemet's tear: A case series. Oman Journal of Ophthalmology, 15(2), 221-224.

Singh, R., et al. (2023). Anterior segment optical coherence tomography in pediatric corneal opacities: A diagnostic boon. Indian Journal of Ophthalmology, 71(5), 2215-2216.

Yadav, S., & Tandon, R. (2023). Descemet's membrane tears following forceps delivery: A case series. Indian Journal of Obstetrics and Gynecology Research, 10(1), 112-115.

Zhao, Y., et al. (2022). Descemetopexy with sulfur hexafluoride for traumatic Descemet membrane detachment in infants. Journal of American Association for Pediatric Ophthalmology and Strabismus, 26(1), 47.e1-47.e4.

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Published

2025-11-20

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Review Article

How to Cite

Descemet’s membrane rupture associated with forceps delivery: A narrative review on diagnosis and management. Research, Society and Development, [S. l.], v. 14, n. 11, p. e152141150127, 2025. DOI: 10.33448/rsd-v14i11.50127. Disponível em: https://rsdjournal.org/rsd/article/view/50127. Acesso em: 5 dec. 2025.