Relationship between mental health and oral lesions: Recent evidence among university students
DOI:
https://doi.org/10.33448/rsd-v15i1.50503Keywords:
Mental health, Stress, Anxiety, Oral lesions, University students, Integrative review.Abstract
Introduction: The mental health of university students has been the subject of increasing attention, the increase in stress, anxiety, and depression among university students has direct repercussions on oral health due to neuroendocrine, immunological, and behavioral changes. This study aims to critically synthesize recent evidence regarding the relationship between mental health — with an emphasis on stress, anxiety, and depression — and oral lesions among university students, discussing their pathophysiological mechanisms, prevalence, clinical interactions, and implications for dental practice. Methodology: The present study consists of an integrative literature review, a method that enables the synthesis of evidence from studies with different methodological approaches. This design was chosen to allow a broad and multifactorial understanding of the relationship between mental health and oral lesions in university students. Results: There is a consistent association between psychological distress and oral manifestations in university students, especially temporomandibular disorders, bruxism, herpes simplex, and recurrent aphthous ulcers. These conditions result from stress-induced immunological and behavioral changes, with a negative impact on quality of life and academic performance. Discussion: Psychological distress among university students is directly associated with oral manifestations such as temporomandibular disorders, bruxism, herpes simplex, and recurrent aphthous ulcers. These findings reinforce the importance of early recognition and an interdisciplinary approach. Conclusion: It is concluded that stress, anxiety, and depression are strongly associated with oral manifestations in university students through biological and behavioral mechanisms. Early recognition of these alterations and an interdisciplinary approach are essential to promote comprehensive care and improve quality of life and academic performance.
References
Barreto, B. R., Drumond, C. L., Carolino, R. A., & Oliveira Júnior, J. K. (2021). Prevalência de disfunção temporomandibular e ansiedade em estudantes universitários. Archives of Health Investigation, 10(9), 1386–1391. https://doi.org/10.21270/archi.v10i9.5401
Barros, R. N. de. (2021). Saúde mental de estudantes universitários: O que está acontecendo nas universidades? [Dissertação de mestrado, Universidade Federal da Bahia]. Repositório Institucional UFBA.
Bueno, C. H. R., & Castro, M. L. (2020). Consequências do estresse na saúde bucal: Revisão de literatura. Revista Científica, 3(19). https://revistas.faculdadefacit.edu.br/index.php/JNT/article/view/721/0
Crossetti, M. G. O. (2012). Revisão integrativa de pesquisa na enfermagem: O rigor científico que lhe é exigido. Revista Gaúcha de Enfermagem, 33(2), 8–9.
Cruz, M. C. F. N., et al. (2008). Condições bucais relacionadas ao estresse: Revisão dos achados atuais. Revista da Faculdade de Odontologia de Porto Alegre, 49(1), 25–30.
De Jesus, C. B. D. (2023). Manifestações orais associadas ao estresse, ansiedade e depressão em estudantes universitários [Trabalho de conclusão de curso, Universidade Estadual de Londrina].
Ferreira, I. V., et al. (2022). Relação entre a recorrência do herpes simples e o estresse durante a pandemia. HU Revista, 48(3), 1–7.
Gil, A. C. (2017). Como elaborar um projeto de pesquisa. Atlas.
Han, S. J. (2025). Association Between Self-Perceived Oral Health, Stress, and Oral Symptoms in University Students: A Cross-Sectional Study. Healthcare, 13(9), 984.
Moreira, M. V., et al. (2024). Efeitos do estresse nas lesões bucais: Revisão de literatura. Brazilian Journal of Implantology and Health Sciences, 6(7), 1609–1617. https://doi.org/10.36557/2674-8169.2024v6n7p1609-1617
Oliveira, M. C. B., et al. (2023). Implicações bucais decorrentes do estresse: Uma revisão de literatura. Thoreauvia, 2(3). https://www.periodicos.univasf.edu.br/index.php/Thoreauvia/article/view/2540
Pereira, A. S., et al. (2018). Metodologia da pesquisa científica. Editora da UFSM.
Rodrigues, Y. M., et al. (2025). Depressão, ansiedade e estresse em universitários e relação com fatores sociodemográficos e psicossociais pós-COVID-19. Cogitare Enfermagem, 30, e96208.
Snyder, H. (2019). Literature review as a research methodology: An overview and guidelines. Journal of Business Research, 104, 333–339. https://doi.org/10.1016/j.jbusres.2019.07.039
Silva, L. F., et al. (2024). Manifestações Orais Associadas ao Estresse, Ansiedade e Depressão em Estudantes Universitários. Archives of Health Investigation, 13(11).
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Copyright (c) 2026 Ádylla de Oliveira Silva, Alessa Izis Souza da Silva Melo, Gabriela Santos Borges, Ana Vitória Andrade dos Santos, Mônica Echilly Alves de Sousa, Filipe Bonfim Nunes, Bruno Almeida Dias, Camilla Thaís Duarte Brasileiro
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