Evaluation of the epidemiological profile of patients with Gestational Trophoblastic Disease treated at the Reference Center of Sergipe

Authors

DOI:

https://doi.org/10.33448/rsd-v10i3.12934

Keywords:

Gestational trophoblastic disease; Epidemiology; Health profile.

Abstract

Objective: To describe the epidemiological profile of patients with Gestational Trophoblastic Disease (DTG) in Sergipe. Methods: This is an observational, descriptive, collaborative study, carried out with female patients diagnosed with GDD through the application of a questionnaire. 86 women with GDD treated at the referral center in Sergipe, at the University Hospital of the Federal University of Sergipe (HU-UFS), were evaluated. Results: After analyzing the 86 questionnaires included, it was observed that most of the studied patients are women aged 35 years or over (57.1%), brown skin was the most prevalent (77.8%) and in great Catholic (52.7%). As for the level of education up to high school, it was the most common (37.2%), more than half of whom had already had a previous pregnancy (60.5%). Most of them have a partnership (92.5%) monthly family income of up to 1 minimum wage (73.6%) and residents of the interior of the state of Sergipe (70.0%). Conclusion: The profile drawn was women aged 35 years or older, mixed race, Catholic, with schooling up to complete high school, with a previous pregnancy history, with a present partnership, with monthly income up to 1 minimum wage and who come from interior of Sergipe to receive treatment at the State Reference Center for DTG.

References

Braga, A. (2018). Doença trofoblástica gestacional. São Paulo: Federação Brasileira das Associações de Ginecologia e Obstetrícia (Febrasgo). (Protocolo Febrasgo – Obstetrícia, nº 23/Comissão Nacional Especializada em Doença Trofoblástica Gestacional). 47(1): 6-17.

Braga, A., Lin, L. H., Maestá, I., Sun, S., Yazaki, U., Elza, M., José, M. & Viggiano, M. (2019). Gestational Trophoblastic Disease in Brazil. Revista Brasileira de Ginecologia e Obstetrícia, 41(4), 211-212

Braga, A.,Uberti, E., M. H., Fajardo, M. C., Viggiano, M., Sun, S. Y., Grillo, B. M. et al. (2014) Epidemiological report on the treatment of patients with gestational trophoblastic disease in 10 Brazilian referral centers. Results after 12 years since International FIGO 2000 consensus. J Reprod Med. 59(5-6): 241-7.

FIGO Oncology Committee. (2002). FIGO staging for gestational trophoblastic neoplasia 2000. FIGO Oncology Committee. Int J Gynaecol Obstet. 77(3):285-7.

Genest, D. R., Berkowitz R. S. & Fisher R. A. Gestational trophoblastic disease. In: Tavassoli FA, Devilee P, editores. World Health Organization classification of tumours. Pathology and genetics: tumors of the breast and female genital organs. Lyon: IARC Press; 2003. p. 250-6.

Gockley, A. A., Melamed, A., Joseph, N. T., Clapp, M., Sun, S. Y., Goldstein, D. P., Horowitz, N. S., & Berkowitz, R. S. (2016). The effect of adolescence and advanced maternal age on the incidence of complete and partial molar pregnancy. Gynecologic oncology, 140(3), 470–473.

Ireson, J., Jones, G., Winter, M. C., Radley, S. C., Hancock, B. W., & Tidy, J. A. (2018). Systematic review of health-related quality of life and patient-reported outcome measures in gestational trophoblastic disease: a parallel synthesis approach. The Lancet. Oncology, 19(1), e56–e64.

Khoo S. K. (2003). Clinical aspects of gestational trophoblastic disease: a review based partly on 25-year experience of a statewide registry. The Australian & New Zealand journal of obstetrics & gynaecology, 43(4), 280–289.

Lurain J. R. (2010). Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. American journal of obstetrics and gynecology, 203(6), 531–539.

Melamed, A., Gockley, A. A., Joseph, N. T., Sun, S. Y., Clapp, M. A., Goldstein, D. P., Berkowitz, R. S., & Horowitz, N. S. (2016). Effect of race/ethnicity on risk of complete and partial molar pregnancy after adjustment for age. Gynecologic oncology, 143(1), 73–76.

Moraes, V. P. D., Marcolino, L. A., Sá, R. A. M. D., Silva, E. P. D., Amim Júnior, J., Rezende Filho, J. F. D., & Braga, A. (2014). Complicações clínicas da gravidez molar. Femina, 42(5), 229-234.

Ngan, H., Seckl, M. J., Berkowitz, R. S., Xiang, Y., Golfier, F., Sekharan, P. K., Lurain, J. R., & Massuger, L. (2018). Update on the diagnosis and management of gestational trophoblastic disease. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 143 Suppl 2, 79–85.

Pereira A.S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. Recuperado de: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1 em 24 de fevereiro de 2021.

Pinto, L. T. C., Costa, A. A. R., Lira, C. M. P., Melo, L. B. & Borba, S. K. M. (2016). Frequência, características clínicas e evolução de pacientes com doença trofoblástica gestacional que desenvolveram complicações. Instituto de Medicina Integral Prof. Fernando Figueira – IMIP. Programa de Iniciação Científica.

Oliveira H. G. S., Santos A. A. P., Lucena T. S., Sanches M. E. T. L., Vieira M. J. O., Teixeira L. M., Oliveira J. C. S., & Rodrigues R. P. G. T. O. (2020). Panorama da doença trofoblástica gestacional numa capital do nordeste. Revista Eletrônica Acervo Saúde, 12(9), e4212.

Soares, P. D., Maestá, I., Costa, O. L., Charry, R. C., Dias, A., & Rudge, M. V. (2010). Geographical distribution and demographic characteristics of gestational trophoblastic disease. The Journal of reproductive medicine, 55(7-8), 305–310.

Sun, R., Zhang, Y., Zheng, W., Tian, Q., An, R., & Xue, Y. (2016). Clinical Characteristics of Gestational Trophoblastic Neoplasia: A 15-Year Hospital-Based Study. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 26(1), 216–221.

Zugaib, M. (2020). Zugaib Obstetrícia. São Paulo: Malone. 4th ed., pp. 611-626.

Published

04/03/2021

How to Cite

MATOS, M. M. R. de .; MENEZES, M. de P. N. .; RODRIGUES, L. M. C. L. .; MENDONÇA, M. N. P. S. . Evaluation of the epidemiological profile of patients with Gestational Trophoblastic Disease treated at the Reference Center of Sergipe. Research, Society and Development, [S. l.], v. 10, n. 3, p. e4110312934, 2021. DOI: 10.33448/rsd-v10i3.12934. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/12934. Acesso em: 14 nov. 2024.

Issue

Section

Health Sciences