Effectiveness of using low level laser for the treatment of TMD: Integrative review





Low level laser; TMD; Orofacial pain; TMJ.


Temporomandibular disorders are characterized either by the presence of pain, swelling and disjunction of the temporomandibular joint or musculature. Thus, the use of the laser has great efficiency to anesthesia on this area, reducing inflammation and discomfort. The objective of this survey was to carry out an integrative review of the literature on the use of laser in the treatment of TMD, highlighting benefits, limitations, effectiveness, relevance and impact for oral health. The guiding question is: how effective is the use of low-level laser in the treatment of TMD? An integrative literature review had been done by searching scientific articles in the electronic databases Web of Science, PubMed and Medline, using the descriptors low-level laser therapy (LLLT), temporomandibular joint dysfunction (TMD) and orofacial, indexed in the period from 2015 to 2020 that dealt with case reports, clinical trial, review, meta-analysis and randomized controlled. There were excluded books and documents, and editorial articles, through the application of the words “and” and “more”. After the eligibility criteria, 7 articles published in English were analyzed. Studies have shown that the use of laser helps in the treatment of TMD regarding the patient comfort, reducing the healing period of the injury, pain and inflammation due to its analgesic and anti-inflammatory capacity. Its effectiveness is due to the increase of collagen content in the wound, stimulating the angiogenesis and the proportion of cells available for healing. Nevertheless, it is required that studies continue to be carried out, so that, matters like these are spread around to population, since this technique is promising for the area.


Cetiner, S., Kahraman, S. A., & Yücetaş, S. (2006). Evaluation of low-level laser therapy in the treatment of temporomandibular disorders. Photomedicine and laser surgery, 24(5), 637–641. https://doi.org/10.1089/pho.2006.24.637.

Carrasco, T. G., Mazzetto, M. O., Mazzetto, R. G., & Mestriner, W., Jr (2008). Low intensity laser therapy in temporomandibular disorder: a phase II double-blind study. Cranio : the journal of craniomandibular practice, 26(4), 274–281. https://doi.org/10.1179/crn.2008.037

Douglas De Oliveira, D. W., Lages, F. S., Guimarães, R. C., Pereira, T. S., Botelho, A. M., Glória, J., Tavano, K., Gonçalves, P. F., & Flecha, O. D. (2017). Do TMJ symptoms improve and last across time after treatment with red (660 nm) and infrared (790 nm) low level laser treatment (LLLT)? A survival analysis. Cranio : the journal of craniomandibular practice, 35(6), 372–378. https://doi.org/10.1080/08869634.2017.

Emshoff, R., Bösch, R., Pümpel, E., Schöning, H., & Strobl, H. (2008). Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 105(4), 452–456. https://doi.org/10.1016/j.tripleo.2007.09.012

Fernandes, T. de F., Pitchon, A. & Pedras, R. B. (2016). Protocolo de disfunção temporomandibular/dtm e dor orofacial/dorf da rede SUSBH.

Lim, P. F., Smith, S., Bhalang, K., Slade, G. D., & Maixner, W. (2010). Development of temporomandibular disorders is associated with greater bodily pain experience. The Clinical journal of pain, 26(2), 116–120. https://doi.org/10.1097/AJP.0b013e3181c507ef.

Machado, B. C., Mazzetto, M. O., Da Silva, M. A., & de Felício, C. M. (2016). Effects of oral motor exercises and laser therapy on chronic temporomandibular disorders: a randomized study with follow-up. Lasers in medical science, 31(5), 945–954. https://doi.org/10.1007/s10103-016-1935-6.

Magri, L. V., Carvalho, V. A., Rodrigues, F. C., Bataglion, C., & Leite-Panissi, C. R. (2017). Effectiveness of low-level laser therapy on pain intensity, pressure pain threshold, and SF-MPQ indexes of women with myofascial pain. Lasers in medical science, 32(2), 419–428. https://doi.org/10.1007/s10103-016-2138-x.

Maia, M. L., Bonjardim, L. R., Quintans, J., Ribeiro, M. A., Maia, L. G., & Conti, P. C. (2012). Effect of low-level laser therapy on pain levels in patients with temporomandibular disorders: a systematic review. Journal of applied oral science: revista FOB, 20(6), 594–602. https://doi.org/10.1590/s1678-77572012000600002.

Melchior, M. de O., et al. (2016). Efeito do tratamento fonoaudiológico após a laserterapia de baixa intensidade em pacientes com DTM: estudo descritivo. CoDAS, 28(6), 818-822. https://doi.org/10.1590/2317-1782/20162015099.

Panhoca, V. H., Lizarelli, R., Nunez, S. C., Pizzo, R. C., Grecco, C., Paolillo, F. R., & Bagnato, V. S. (2015). Comparative clinical study of light analgesic effect on temporomandibular disorder (TMD) using red and infrared led therapy. Lasers in medical science, 30(2), 815–822. https://doi.org/10.1007/s10103-013-1444-9.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica.

Petrucci, A., Sgolastra, F., Gatto, R., Mattei, A., & Monaco, A. (2011). Effectiveness of low-level laser therapy in temporomandibular disorders: a systematic review and meta-analysis. Journal of orofacial pain, 25(4), 298–307.

Rodrigues, C. A., Melchior, M. O., Valencise Magri, L., & Mazzetto, M. O.(2020). Can the severity of orofacial myofunctional conditions interfere with the response of analgesia promoted by active or placebo low-level laser therapy? Cranio: the journal of craniomandibular practice, 38(4), 240–247. https://doi.org/10.1080/08869634.2018.1520950.

Venancio, R., Camparis, C. M., & Lizarelli, R. (2005). Low intensity laser therapy in the treatment of temporomandibular disorders: a double-blind study. Journal of oral rehabilitation, 32(11), 800–807. https://doi.org/10.1111/j.1365-2842.2005.01516.x

Whittemore, R., & Knafl, K. (2005). The integrative review: updated methodology. Journal of advanced nursing, 52(5), 546–553. https://doi.org/10.1111/j.1365-2648.2005.03621.x.

Xu, G. Z., Jia, J., Jin, L., Li, J. H., Wang, Z. Y., & Cao, D. Y. (2018). Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis. Pain research & management, 2018, 4230583. https://doi.org/10.1155/2018/4230583

Zokaee, H., Zahmati, A. H. A., Mojrian, N., Boostani, A., & Vaghari, M. (2018). Efficacy of Low Level Laser Therapy on Orofacial Pain: A Literature Review. Advances in human biology, 8(2), 70-73. https://doi.org/10.4103/AIHB.AIHB_2_18.



How to Cite

BORBA, C. A. A. .; TÔRRES, D. J. S. .; ALVES-SILVA, E. G. .; SÁ, R. A. G. de .; MELO, E. L. de .; GERBI, M. E. M. de M. .; BISPO, M. E. A. .; MENEZES, M. R. A. de . Effectiveness of using low level laser for the treatment of TMD: Integrative review . Research, Society and Development, [S. l.], v. 10, n. 4, p. e4510413282, 2021. DOI: 10.33448/rsd-v10i4.13282. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13282. Acesso em: 11 apr. 2021.



Review Article