Lesão renal aguda na COVID-19 e abordagem multiprofissional

Ana Caroline Gusmão de  Matos; Thiago Vaz de  Andrade; Nathalia Costa Macedo  Noronha; Thayná Bezerra  Lima; Carmem Isaura Salles do  Nascimento; Alícia Calinne Melo   Santos; Valéria Soares de Jesus Santana; Luana Godinho Maynard; Carla Viviane Freitas de  Jesus

doi:10.33448/rsd-v10i3.13436

Authors

Ana Caroline Gusmão de Matos Universidade Tiradentes https://orcid.org/0000-0002-4451-0243
Thiago Vaz de Andrade Universidade Tiradentes https://orcid.org/0000-0001-7950-4073
Nathalia Costa Macedo Noronha Universidade Tiradentes https://orcid.org/0000-0003-0801-1217
Thayná Bezerra Lima Universidade Tiradentes https://orcid.org/0000-0001-7574-8820
Carmem Isaura Salles do Nascimento Universidade Tiradentes https://orcid.org/0000-0002-3000-8340
Alícia Calinne Melo Santos Universidade Tiradentes https://orcid.org/0000-0001-9173-4760
Valéria Soares de Jesus Santana Universidade Tiradentes https://orcid.org/0000-0001-6558-0534
Luana Godinho Maynard Universidade Tiradentes https://orcid.org/0000-0003-0950-4742
Carla Viviane Freitas de Jesus Universidade Tiradentes https://orcid.org/0000-0002-7775-6610

DOI:

https://doi.org/10.33448/rsd-v10i3.13436

Keywords:

Acute Kidney Injury; Coronavirus Infections; Patient Care Team; Physiological phenomena.

Abstract

Aim: To identify the relationship between COVID-19 and acute kidney injury, as well as the role of the multiprofessional approach in this scenario. Methodology: This is a narrative review carried out from the PubMed, SciELO and LILACS databases, using the descriptors "COVID-19" and "Acute Kidney Injury". The inclusion criteria were: original published studies available in full for reading, published in the last 5 years, in Portuguese, English and / or Spanish. Veterinary articles were excluded, as well as those that evaluated patients with chronic kidney diseases previous to infection by COVID-19 or transplanted patients, isolated abstracts and editorial letters. Results: SARS-CoV-2 uses angiotensin 2-converting enzyme and type 2 transmembrane serine proteases to invade human cells, causing a systemic inflammatory response because of cytokine storm; direct cytotropic effect induced by virus; and acute tubular necrosis, due to multiple organ failure and shock. Rhabdomyolysis contributes to this condition. Clinically, patients with acute kidney injury and COVID-19 may present genitourinary symptoms, diarrhea, proteinuria, hematuria and changes in urea and creatinine. The approach to the nephrological patient in a pandemic context involves reinforcement of preventive measures against the new virus, effective health management and collaboration between doctors and nurses of different specialties, especially intensivists and nephrologists. Conclusion: SARS-CoV-2 infection can cause acute kidney injury due to direct viral toxicity or dysregulation of immunological mechanisms. The clinical picture in these cases is marked by symptoms of kidney failure and infection. The synergistic performance of the multiprofessional health team and health managers is essential in this scenario.

References

Alrubaye, R., & Choudhary, H. (2020). Severe Rhabdomyolysis in a 35-Year-old Woman with COVID-19 due to SARS-CoV-2 Infection: A Case Report. The American Journal of Case Reports, 21, e926733-1.

Bajwa, H., Riaz, Y., Ammar, M., Farooq, S., & Yousaf, A. (2020). The dilemma of renal involvement in COVID-19: a systematic review. Cureus, 12(6), e8632.

Betonico, G. N., Lima, E. Q., & Tome, A. C. N. (2020). Challenges in COVID-19 medical response: a nephrology perspective. Eur J Clin Invest, e13328.

Bosch, X., Poch, E., & Grau, J. M. (2009). Rhabdomyolysis and acute kidney injury. New England Journal of Medicine, 361(1), 62-72.

Cha, R. H., Joh, J. S., Jeong, I., Lee, J. Y., Shin, H. S., Kim, G., & Kim, Y. (2015). Renal complications and their prognosis in Korean patients with Middle East respiratory syndrome-coronavirus from the central MERS-CoV designated hospital. Journal of Korean medical science, 30(12), 1807–1814.

Cheng, Y., Luo, R., Wang, K., Zhang, M., Wang, Z., Dong, L., Li, J., Yao, Y., Ge, S., & Xu, G. (2020). Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney international, 97(5), 829-838.

Chenna, A., Konala, V. M., Bose, S., Roy, S., Madhira, B. R., Gayam, V., Naramala, S., & Adapa, S. (2020). Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade. Case reports in nephrology, 2020.

Connors, J. M., & Levy, J. H. (2020). Thromboinflammation and the hypercoagulability of COVID‐19. Journal of Thrombosis and Haemostasis, 18(7), 1559-1561.

Cui, X., Yu, X., Wu, X., Huang, L., Tian, Y., Huang, X., Zhang, Z., Cheng, Z., Guo, Q., Zhang, Y., Cai, Y., & Zhan, Q. (2020). Acute kidney injury in patients with the coronavirus disease 2019: a multicenter study. Kidney and Blood Pressure Research, 45(4), 612-622.

D’Marco, L., Puchades, M. J., Romero-Parra, M., Gimenez-Civera, E., Soler, M. J., Ortiz, A., & Gorriz, J. L. (2020). Coronavirus disease 2019 in chronic kidney disease. Clinical kidney journal, 13(3), 297-306.

Farouk, S. S., Fiaccadori, E., Cravedi, P., & Campbell, K. N. (2020). COVID-19 and the kidney: what we think we know so far and what we don’t. Journal of nephrology, 1-6.

Goldfarb, D. S., Benstein, J. A., Zhdanova, O., Hammer, E., Block, C. A., Caplin, N. J., Thompson, N., & Charytan, D. M. (2020). Impending shortages of kidney replacement therapy for COVID-19 patients. Clinical Journal of the American Society of Nephrology, 15(6), 880-882.

Gupta, R. K., Bhargava, R., Shaukat, A. A., Albert, E., & Leggat, J. (2020). Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease: a report of 2 cases. BMC nephrology, 21(1), 1-7.

Hirsch, J. S., Ng, J. H., Ross, D. W., Sharma, P., Shah, H. H., Barnett, R. L., Hazzan, A. D., Fishbane, S., Jhaveri, K. D., & Northwell COVID-19 Research Consortium. (2020). Acute kidney injury in patients hospitalized with COVID-19. Kidney international, 98(1), 209-218.

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N. W., Nitsche, A., Müller, M. A., Drosten, C., & Pöhlmann, S. (2020). SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. cell, 181(2), 271-280.

Li, B., Yang, J., Zhao, F., Zhi, L., Wang, X., Liu, L., Bi, Z., & Zhao, Y. (2020a). Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clinical Research in Cardiology, 109(5), 531-538.

Li, Z., Wu, M., Yao, J., Guo, J., Liao, X., Song, S., Li, J., Duan, G., Zhou, Y., Wu, X., Zhou, Z., Wang, T., Hu, M., Chen, X., Fu, Y., Lei, C., Dong, H., Xu, C., Hu, Y., Han, M., Zhou, Y., Jia, H., Chen, X., & Yan, J. (2020b). Caution on kidney dysfunctions of COVID-19 patients. MedRxiv. http://dx.doi.org/10.2139/ssrn.3559601.

Lipton, M., Kavanagh, C. R., Mahajan, R., Jain, N. G., Uy, N. S., Dogra, S., & Lin, F. (2020). Role of pediatric nephrologists in managing adults with AKI due to COVID-19. Pediatric Nephrology, 35(11), 2019-2022.

McGuire, A. L., Aulisio, M. P., Davis, F. D., Erwin, C., Harter, T. D., Jagsi, R., Klitzman, R., Macauley, R., Racine, E., Wolf, S., M., Wynia, M., Wolpe, P. R., & COVID-19 Task Force of the Association of Bioethics Program Directors (ABPD). (2020). Ethical challenges arising in the COVID-19 pandemic: An overview from the Association of Bioethics Program Directors (ABPD) task force. The American Journal of Bioethics, 20(7), 15-27.

Moitinho, M. S., Belasco, A. G. D. S., Barbosa, D. A., & Fonseca, C. D. D. (2020). Acute Kidney Injury by SARS-CoV-2 virus in patients with COVID-19: an integrative review. Revista brasileira de enfermagem, 73.

Mukherjee, A., Ghosh, R., & Aftab, G. (2020). Rhabdomyolysis in a patient with coronavirus disease 2019. Cureus, 12(7).

Na, K. R., Kim, H. R., Ham, Y., Choi, D. E., Lee, K. W., Moon, J. Y., Kim, Y. S., Cheon, S., Sohn, K. M., Kim, J., Kim, S., Jeong, H., & Jeon, J. W. (2020). Acute kidney injury and kidney damage in COVID-19 patients. Journal of Korean medical science, 35(28), e257.

Pan, X. W., Xu, D., Zhang, H., Zhou, W., Wang, L. H., & Cui, X. G. (2020). Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis. Intensive care medicine, 46(6), 1114-1116.

Parsons, J. A., & Martin, D. E. (2020). A call for dialysis-specific resource allocation guidelines during COVID-19. The American Journal of Bioethics, 20(7), 199-201.

Pereira A. S., Shitsuka D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. UFSM. https://www.ufsm.br/app/uploads/sites/358/2019/02/ Metodologia-da-Pesquisa-Cientifica_final.pdf em: 14/03/2021.

Richardson, S., Hirsch, J. S., Narasimhan, M., Crawford, J. M., McGinn, T., Davidson, K. W., & Northwell COVID-19 Research Consortium. (2020). Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. Jama, 323(20), 2052-2059

Rossi, G. M., Delsante, M., Pilato, F. P., Gnetti, L., Gabrielli, L., Rossini, G., Parenti, E., Maccari, C., Greco, P., Mario, F. D., Maggiore, U., Regolisti, G., & Fiaccadori, E. (2020). Kidney biopsy findings in a critically ill COVID-19 patient with dialysis-dependent acute kidney injury: a case against “SARS-CoV-2 nephropathy”. Kidney international reports, 5(7), 1100-1105.

Shi, Q., Zhao, K., Yu, J., Jiang, F., Feng, J., Zhao, K., Zhang, X., Chen, X., Hu, P., Hong, Y., Li, M., Liu, F., Chen, C., & Wang, W. (2020). Clinical characteristics of 101 COVID-19 nonsurvivors in Wuhan, China: a retrospective study. MedRxiv. https://doi.org/10.1101/2020.03.04.20031039.

Simões e Silva, A. C., Silveira, K. D., Ferreira, A. J., & Teixeira, M. M. (2013). ACE2, angiotensin‐(1‐7) and M as receptor axis in inflammation and fibrosis. British journal of pharmacology, 169(3), 477-492.

Su, H., Yang, M., Wan, C., Yi, L. X., Tang, F., Zhu, H. Y., Yi, F., Yang, H., Fogo, A. B., Nie, X., & Zhang, C. (2020). Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney international, 98(1), 219-227.

Suassuna, J. H. R., Lima, E. Q. D., Rocha, E., Castro, A., Burdmann, E. D. A., Carmo, L. P. D. F. D., Yu, L., Ibrahim, M. Y., Betônico, G. N., Neto, A. L. C., Ávila, M. O. N., Gonçalves, A. R. R., Costa, C. B. S., Bresolin, N. L., Abreu, A. P., Lobo, S. M. A., & Nascimento, M. M. D. (2020). Nota técnica e orientações clínicas sobre a Injúria Renal Aguda (IRA) em pacientes com Covid-19: Sociedade Brasileira de Nefrologia e Associação de Medicina Intensiva Brasileira. Brazilian Journal of Nephrology, 42(2), 22-31.

Taxbro, K., Kahlow, H., Wulcan, H., & Fornarve, A. (2020). Rhabdomyolysis and acute kidney injury in severe COVID-19 infection. BMJ Case Reports CP, 13(9), e237616.

Ulu, S., Gungor, O., Gok Oguz, E., Hasbal, N. B., Turgut, D., & Arici, M. (2020). COVID-19: a novel menace for the practice of nephrology and how to manage it with minor devastation?. Renal failure, 42(1), 710-725.

Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., Zhao, Y., Li, Y., Wang, X., & Peng, Z. (2020a). Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. Jama, 323(11), 1061-1069.

Wang, L., Li, X., Chen, H., Yan, S., Li, D., Li, Y., & Gong, Z. (2020b). Coronavirus disease 19 infection does not result in acute kidney injury: an analysis of 116 hospitalized patients from Wuhan, China. American journal of nephrology, 51(5), 343-348.

Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C. L., Abiona, O., Graham, B. S., & McLellan, J. S. (2020). Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science, 367(6483), 1260-1263.

Yang, X., Yu, Y., Xu, J., Shu, H., Xia, J., Liu, H., Wu, Y., Zhang, L., Yu, Z., Fang, M., Yu, T, Wang, Y., Pan, S., Zou, X., Yuan, S., & Shang, Y. (2020). Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine, 8(5), 475-481.

Zhang, G., Hu, C., Luo, L., Fang, F., Chen, Y., Li, J., Peng, Z., & Pan, H. (2020). Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China. Journal of Clinical Virology, 127, 104364.

Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Xiang, J., Wang, Y., Song, B., Gu, X., Guan, L., Wei, Y., Li, H., Wu, X., Xu, J., Tu, S., Zhang, Y., & Cao, B. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The lancet, 395(10229), 1054-1062.

Zou, X., Chen, K., Zou, J., Han, P., Hao, J., & Han, Z. (2020). Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Frontiers of medicine, 14, 185–192.

Zutt, R., Van Der Kooi, A. J., Linthorst, G. E., Wanders, R. J. A., & De Visser, M. (2014). Rhabdomyolysis: review of the literature. Neuromuscular Disorders, 24(8), 651-659.

Acute kidney injury at COVID-19 and a multiprofessional approach

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