Clinical-pathological analysis of squamous cell carcinoma on the oral floor: A case report




Carcinoma, Squamous Cell; Mouth Neoplasms; Diagnosis.


Squamous cell carcinoma of the lower lip is one of the most common malignant neoplasms of the oral and maxillofacial region. The aim of the present study was to report a clinical case of squamous cell carcinoma on the oral floor. Female patient, 57 years old, smoker and alcoholic for a period of ten years, attended the dental clinic showing an increase in volume in the region of the oral floor, with painful symptoms, hardened consistency, and duration of 2 years. Under the clinical hypothesis of oral squamous cell carcinoma, an incisional biopsy was performed, which revealed an epithelial malignant neoplasm showing nests and islands of cells with a hyperchromatic nucleus, moderate nuclear and cellular pleomorphism, and keratin pearls. The stroma exhibited a moderate predominantly mononuclear inflammatory infiltrate. Based on the definitive diagnosis of squamous cell carcinoma, the patient was referred to a cancer referral center. The findings of the present case underscore the importance of a correct diagnosis and highlight the importance of a thorough clinical examination, making it necessary to correlate the clinical, radiographic and histopathological data for the correct diagnosis.


Levi, P. A., Kim, D. M., Harsfield, S. L., & Jacobson, E. R. (2005). Squamous cell carcinoma presenting as an endodontic-periodontic lesion. J Periodontol, 76(10):1798-1804.

Maia, H. C., Pinto, N. A., Pereira, J. S, Medeiros, A. M., Silveira, E. J., & Miguel, M. C. (2016). Lesões orais potencialmente malignas: correlações clínico-patológicas. Einstein, 14(1):35-40.

Morais, E. F., Silva, L. P., Mororó, A. B. G., Pinto, E. P., Taylor, A. M., Pinto, L. P., & Souza, L. B. (2019). Carcinoma mucoepidermoide intraósseo maxilar: um raro relato de caso. J Bras Patol Med Lab, (5): 540-549.

Passarelli, D. H. C., Gobbo, S. R., Campos, M., & Oliveira, P. C. (2011). A Interdisciplinaridade no diagnóstico de carcinoma epidermóide. Rev. Odontol. Univ. Cid, 23(3): 273-277.

Pereira, A. C. (2001). Análise de carcinomas epidermóides por meio de radiografia panorâmica e tomografia computadorizada. Pesqui Odontol Bras, 15(4): 320-326.

Ledesma-Montes, C., Hernández-Guerrero, J. C., Durán-Padilla, M. A., & Alcántara-Vázquez, A. (2018). Squamous cell carcinoma of the tongue in patients older than 45 years. Braz. Oral Res, 32(123): 1-9.

Rege, I. C. C. (2013). Carcinoma epidermóide no seio maxilar: Uma revisão analítica da literatura. Sci Invest Dent, 16(1): 29-42.

Rohde, M. (2014). 18F-fluoro-deoxy-glucose-positron emission tomography/ computed tomography in diagnosis of head and neck squamous cell carcinoma: A systematic review and meta-analysis. European Journal of Cancer, 1(50): 2271–2279.

Santos, F. S. (2010). Carcinoma epidermóide de língua: diagnóstico, tratamento e acompanhamento. Arq Ciênc Saúde, 17(4):198-200.

Vanini, J. V. (2019). Ressonância magnética para avaliação de metástases de carcinoma epidermoide oral em linfonodos cervicais: revisão da literatura. Radiologia Oral, 1(1):1-8.



How to Cite

ARAÚJO , J. M. do N. .; OLIVEIRA, B. R. de .; SILVA, E. A. dos R. .; NASCIMENTO, F. de S. .; SANTOS, G. A. dos .; TODT, G. D. .; BRITO, H. L. .; SANTOS, Ísis S. C. dos .; SANTOS, J. F. R. .; COSTA, J. M. .; OLIVEIRA NETO, J. A. de .; LOESER, J. M. S. .; SEABRA, L. G. .; SANTOS, L. C.; BRANDÃO NETO, M. G. .; NOGUEIRA, M. F. .; JESUS , P. V. S. de .; GOULART, T. de O. .; VANDERLEY, V. V. M. M. .; LEITE, R. B. . Clinical-pathological analysis of squamous cell carcinoma on the oral floor: A case report. Research, Society and Development, [S. l.], v. 10, n. 3, p. e46810313639, 2021. DOI: 10.33448/rsd-v10i3.13639. Disponível em: Acesso em: 14 apr. 2021.



Health Sciences