Amputation lower limb due to Diabetes Mellitus the states and regions of Brazil




Amputation; Lower Extremity; Diabetic foot; Hospital information system.


Amputation due to Diabetes Mellitus consists of a worldwide dimension of severity, frequently occurring in populations of low socioeconomic status in inadequate conditions of hygiene and lack of access to health facilities. The diabetic foot is associated with factors such as diabetic neuropathy, peripheral arterial disease and infection, contributing to a prognosis of ulceration and / or necrosis in the finger, part of the foot, complete foot and / or leg, amputation and death. The aim of this study was to determine the epidemiological profile of amputation in lower limbs due to diabetes mellitus in the regions and states of Brazil. The research was carried out through the databases of the Registry of lower limb amputation procedures in the Hospital Information System (SIH / SUS) for the period from 2000 to 2020. Amputation was more prevalent in the southeast, northeast, south, respectively. midwest and north. The findings of this study also indicate the need for early promotion of screening, diagnosis, treatment, rehabilitation, in order to enhance healing and return to activities of daily and professional life, avoiding amputation and death.


American Diabetes Association. (2019). Complicações microvasculares e cuidados com os pés: padrões de cuidados médicos em diabetes - 2019. Diabetes Care, 42 (1), S124-S138.

Assumpção, E. C, Pitta, G. B. B, Macedo A. C. L, Mendonça G. B, Albuquerque, L. C. A, Lyra, L. C. B., Timbó, R. M., & Buarque, T. L. L. (2009). Comparação dos fatores de risco para amputações maiores e menores em pacientes diabéticos de um Programa de Saúde da Família. Jornal Vascular Brasileiro, 8 (2),133-138.

Atlas, I. D. (2013). Online version of IDF Diabetes Atlas: http://www. idf. org/diabetesatlas. International Diabetes Federation.

Bandyk, D.F., (2018). The diabetic foot: Pathophysiology, evaluation, and treatment. Semin Vasc Surg. 31(2-4):43-48. 10.1053/j.semvascsurg.2019.02.001. Epub 2019 Feb 6. PMID: 30876640.

Bém, R., Dubský, M., Fejfarová, V., Husáková, J., & Wosková, V. (2020). Pé diabético. Diabetická noha. Vnitrni lekarstvi, 66 (2), 92–97.

Boulton, A. J., Vileikyte, L., Ragnarson-Tennvall, G., & Apelqvist, J. (2005). The global burden of diabetic foot disease. The Lancet, 366 (9498), 1719-1724.

Brocco, E., Ninkovic, S., Marin, M., Whisstock, C., Bruseghin, M., Boschetti, G., & Volpe, A. (2018). Diabetic foot management: multidisciplinary approach for advanced lesion rescue. The Journal of cardiovascular surgery, 59(5), 670-684.

DATASUS – Sistema de Informações Hospitalares (SIH/SUS). (2021).>.

Grennan, D. (2019). Diabetic foot ulcers. Jama, 321(1), 114-114.

International Diabetes Federation. (2021).

Geiss, L. S., Li, Y., Hora, I., Albright, A., Rolka, D., & Gregg, E. W. (2019). Resurgence of diabetes-related nontraumatic lower-extremity amputation in the young and middle-aged adult US population. Diabetes Care, 42 (1), 50-54.

Miyajima, S., Shirai, A., Yamamoto, S., Okada, N., & Matsushita, T. (2006). Risk factors for major limb amputations in diabetic foot gangrene patients. Diabetes research and clinical practice, 71(3), 272-279.

Nunes, M. A. P., Resende, K. F., Castro, A. A., Pitta, G. B. B., Figueiredo, L. F. P. D., & Miranda Jr, F. (2006). Fatores predisponentes para amputação de membro inferior em pacientes diabéticos internados com pés ulcerados no estado de Sergipe. Jornal Vascular Brasileiro, 5(2), 123-130.

Schaper, N. C. (2012). Lessons from eurodiale. Diabetes/metabolism research and reviews, 28, 21-26.

Sen, P., Demirdal, T., & Emir, B. (2019). Meta‐analysis of risk factors for amputation in diabetic foot infections. Diabetes/metabolism research and reviews, 35(7), e3165.

Pecoraro, R. E., Reiber, G. E., & Burgess, E. M. (1990). Pathways to diabetic limb amputation: basis for prevention. Diabetes care, 13(5), 513-521.

Peng, B., Min, R., Liao, Y., & Yu, A. (2021). Development of Predictive Nomograms for Clinical Use to Quantify the Risk of Amputation in Patients with Diabetic Foot Ulcer. Journal of Diabetes Research, 2021.

Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. UFSM.

Pitta, G. B. B., Castro, A. A., Soares, A. M. M. N., Maciel, C. D. J. J., da Silva, J. D. M., Muniz, V. M. T., & Asmar, S. B. (2019). Perfil dos pacientes portadores de pé diabético atendidos no Hospital Escola José Carneiro e na Unidade de Emergência Armando Lages. Jornal Vascular Brasileiro, 4(1), 5-10.

Rezende, K. F., Ferraz, M. B., Malerbi, D. A., Melo, N. H., Nunes, M. P., Pedrosa, H. C., & Chacra, A. R. (2009). Direct costs and outcomes for in patients with diabetes mellitus and foot ulcers in a developing country: The experience of the public health system of Brazil. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 3(4), 228-232.

Rorive, M., & Scheen, A. J. (2019). Actualités dans la prise en charge du pied diabétique [News in the management of diabetic foot]. Revue medicale suisse, 15(659), 1448–1452.

Santos, V. P. D., Silveira, D. R. D., & Caffaro, R. A. (2006). Risk factors for primary major amputation in diabetic patients. Sao Paulo Medical Journal, 124(2), 66-70.

Stern, J. R., Wong, C. K., Yerovinkina, M., Spindler, S. J., See, A. S., Panjaki, S., & Nowygrod, R. (2017). A meta-analysis of long-term mortality and associated risk factors following lower extremity amputation. Annals of vascular surgery, 42, 322-327.

Wrobel, J. S., Mayfield, J. A., & Reiber, G. E. (2001). Geographic variation of lower-extremity major amputation in individuals with and without diabetes in the Medicare population. Diabetes care, 24(5), 860-864.



How to Cite

SILVA, A. A. S. da; CASTRO, A. A. .; BOMFIM, L. G. de; PITTA, G. B. B. . Amputation lower limb due to Diabetes Mellitus the states and regions of Brazil. Research, Society and Development, [S. l.], v. 10, n. 4, p. e11910413837, 2021. DOI: 10.33448/rsd-v10i4.13837. Disponível em: Acesso em: 11 apr. 2021.



Health Sciences