Development, characterization and application of silver nanoparticles stabilized with sunflower (Helianthus annuus) extract




Nanoparticles silver; Antimicrobial; Helianthus annuus.


The use of nanoparticles has been applied in several areas of pharmacology, due to its advantages before absorption, distribution and its effect on disease, especially when it is compose of natural products due to its ability to reduce possible toxic effects of the final product. The study aimed to analyze the effect of Helianthus Annuus extract (AgNP@Ha) in the synthesis of a silver nanoparticle and to evaluate its antimicrobial action against gram-positive, gram-negative bacteria and fungi. The production of the nanoparticle was carried out by stirring over a heated magnetic plate until the complete configuration of the nanoparticle was formed, then, the extract was used to stabilize the nanoparticle, its size was verified by means of UV-VIS. Microbiological analysis was performed on a plate, measuring the size of the inhibitory halo formed. An AgNP@Ha 414 nm that were stabilized using sunflower was obtained with halo formation effect on S. aureus (16 mm), E. coli (12 mm) and P. aeruginosa (10 mm) strains, while AgNPs that were not stabilized with sunflower did not show the inhibitory halo. Through this research it was possible to prove the improvement of pharmacological effect and production efficiency of silver nanoparticles when using sunflower seed extract as a stabilizer The synthesis of silver nanoparticles using the extract of Helianhtus annuus seeds promoted a more environmentally friendly, simple, efficient and low cost approach to obtain nanoparticles, becoming an excellent product with antimicrobial potential to be marketed in addition to serving as a subsidy for further research.

Author Biographies

Taciany Alves Batista Lemos, Centro Universitário UNIFACID/WYDEN

Enfermeira, Mestre em Terapia Intensiva pela SOBRAT.

Deuzuita dos Santos Freitas Viana, Centro Universitário UNIFACID/WYDEN

Dr. Materials Engineering Graduate Program, Federal Institute of Education, Science and Technology of Piauí, Central Campus

Vicente Galber Freitas Viana, Universidade Federal do Piauí

Doutora em Ciências, Mestre em Engenharia Mecânica, Coordenadora das Engenharias da UNIFACID.

Matheus Henrique da Silva Lemos, Universidade Federal do Piauí

Enfermeiro. Mestrando em Ciências e Saúde pela Universidade Federal do Piauí (UFPI)

Girlene Soares de Figueirêdo, Universidade Federal do Piauí

Doutora em Biotecnologia com ênfase em Microbiologia do Centro de Ciências da Saúde da Universidade Federal do Piauí (UFPI)


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How to Cite

LEMOS, T. A. B. .; VIANA, D. dos S. F. .; VIANA, V. G. F. .; LEMOS, M. H. da S. .; FIGUEIRÊDO, G. S. de . Development, characterization and application of silver nanoparticles stabilized with sunflower (Helianthus annuus) extract. Research, Society and Development, [S. l.], v. 10, n. 6, p. e11710615533, 2021. DOI: 10.33448/rsd-v10i6.15533. Disponível em: Acesso em: 20 jun. 2021.



Health Sciences