Updates on the relationship insomnia and hypertension in the elderly

Authors

DOI:

https://doi.org/10.33448/rsd-v10i8.17276

Keywords:

Insomnia; Hypertension; Elderly.

Abstract

Introduction: Insomnia is defined as a persistent difficulty with the onset, duration, consolidation or quality of sleep. This disorder has been studied as a possible predisposing factor for Cardiovascular Disease (CVD) and Systemic Arterial Hypertension (SAH), mainly affecting the elderly, since hypertension and insomnia are more prevalent in this age group. Objective: This article aims to develop a literary review on the association between insomnia and hypertension, in an elderly population, in search of a possible relationship between cause and effect. Methodology: A search for articles, published in the last 5 years, in the VHL and LILACS databases, in Portuguese and English, using the descriptors insomnia, hypertension and elderly, was carried out. Results: There are similarities between the pathophysiology of Insomnia and SAH. Three theories propose to explain this relationship, the psychogenic, the neurological and the mood mismatch, which cause neurological and hormonal dysfunctions. Conclusion: It was found that there is still no consensus among the studies, despite some pathophysiological, epidemiological and clinical relationships between SAH and Insomnia, since research is still recent and evolving.

References

Aggarwal, B., Makarem, N., Shah, R., Emin, M., Wei, Y, St-Onge, M.-P, & Jelic, S. (2018). Effects of Inadequate Sleep on Blood Pressure and Endothelial Inflammation in Women: Findings From the American Heart Association Go Red for Women Strategically Focused Research Network. Journal of the American Heart Association, 7:e008590. https://www.ahajournals.org/doi/10.1161/JAHA.118.008590

Carter, J. R., Grimaldi, D., Fonkoue, I. T., Medalie, L., Mokhlesi, B & Cauter E. V. (2018). Assessment of sympathetic neural activity in chronic insomnia: evidence for elevated cardiovascular risk. Sleep, 41(6): zsy048. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995193/

Levenson, J. C., Rollman, B. L., Ritterband, L. M., Strollo, P. J., Smith, K. J. & Yabes, J. G. et al. (2017). Hypertension with unsatisfactory sleep health (HUSH): study protocol for a randomized controlled trial. Trials, 18:256. https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-017-2001-9#citeas

Liu, R.-Q., Zhengmin, Q., Edwin, T., Jen-Jen, C., Alan, Z. & Yuan-Tao et al. (2016). Poor sleep quality associated with high risk of hypertension and elevated blood pressure in China: Results from a large population-based study. Hypertension research, 39(1): 54-9. https://pesquisa.bvsalud.org/portal/resource/pt/mdl-26333359

Lu, Y., Wang, X., Yang, G., Liu, X. & X, M. (2018). Effects of Chronic Intractable Insomnia on Inflammatory Cytokines, Blood Pressure Characteristics, and Antihypertensive Efficacy in Hypertensive Patients. Medical science monitor: international medical journal of experimental and clinical research, 24: 9259–9264. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320642/

Mendoza-Fernandez, J. (2018). What should we tell our worried patients with insomnia about blood pressure? Sleep Medicine Reviews, 41, 1-2. https://www.sciencedirect.com/science/article/abs/pii/S1087079218301084?via%3Dihub

Mcgrath, E. R., Espie, C. A., Power, A., Murphy, A. W., Newell, J. & Kelly, C. et al. (2017). Sleep to Lower Elevated Blood Pressure: A Randomized Controlled Trial (SLEPT). American Journal of Hypertension, 30(3), 319-327. https://academic.oup.com/ajh/article/30/3/319/2927604

Uchmanowicz, I., Markiewicz, K., Uchmanowicz, B., Kołtuniuk, A. & Rosińczuk, J. (2019). The relationship between sleep disturbances and quality of life in elderly patients with hypertension. Clin Interv Aging., 14:155-165. https://www.dovepress.com/the-relationship-between-sleep-disturbances-and-quality-of-life-in-eld-peer-reviewed-article-CIA

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Santa Maria/RS. Ed. UAB/NTE/UFSM

Hart, C. E., Head, G. A., Carter, J. R., Wallin, B. G., May, C. M. & Hamza. et al. (2017). Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization. Am J Physiol Heart Circ Physiol. 312 (5): H1031 – H1051. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146303/

Halassa, M. M., Florian, C., Fellin, T., Munoz, J. R., Lee S. & Abel T. et al. (2010). Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron. 2009;61:213–19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673052/

Levenson, J. C., Kay, D. B. & Buysse D. J. (2015). The Pathophysiology of Insomnia. Chest. 147(4): 1179–1192. ncbi.nlm.nih.gov/pmc/articles/PMC4388122/

Vgontzas AN; Liao D; Bixler EO; Chrousos GP & Vela-Bueno A. (2009) Insomnia with objective short sleep duration is associated with a high risk for hypertension. Sleep. 32(4):491–497. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663863/

Marques, A. P., Szwarcwald, C. L., Pinhares, D. C., Rodrigues, J. M., Almeida, W. S. & Romero, D. Fatores associados à hipertensão arterial: uma revisão sistemática. (2020). Ciênc. saúde coletiva. 25 (6). https://www.scielo.br/j/csc/a/S3rGV7YyJgStLFgcBQxjkfK/?lang=pt#

Vital, T. G., Silva, I. O. & Paz, F. A. N. (2020). Hipertensão arterial e os fatores de risco relacionados ao trabalho: uma revisão de literatura. Research, Society and Development, v. 9, n.7. https://www.rsdjournal.org/index.php/rsd/article/view/5085

Freitas, C. B., Veloso, T. C. P., Segundo, L. P. S., Sousa, F. P. G., Galvão, B. S. & Negaishi, C. Y. (2020). Influência da prática de exercícios físicos na redução da hipertensão arterial. Research, Society and Development, v. 9, n.4. https://www.rsdjournal.org/index.php/rsd/article/view/3020/2311

Published

10/07/2021

How to Cite

FREITAS, L. Z. de .; SOUZA, H. C. de .; COUTINHO, L. S. B. . Updates on the relationship insomnia and hypertension in the elderly . Research, Society and Development, [S. l.], v. 10, n. 8, p. e18710917276, 2021. DOI: 10.33448/rsd-v10i8.17276. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/17276. Acesso em: 25 apr. 2024.

Issue

Section

Health Sciences